What substances does a medication such as Thioctacid 600 BV contain? Instructions for use, the composition and form of this drug will be described below. We will also provide information on how much this remedy costs, for what purpose it is prescribed to patients, and whether it has contraindications.
Composition, description, form and packaging of the medication
You can buy the medication in two different forms:
- Oral preparation "Thioctacid BV" (tablets). The instruction for use states that it has a convex shape, as well as a yellow shell or with a greenish tint. On sale, such tablets come in bottles of 30 pieces. The active substance of this tool is thioctic acid. The medication also includes additional elements in the form of low-substituted hydroxypropyl cellulose, magnesium stearate, hydroxypropyl cellulose, hypromellose, macrogol 6000, quinoline yellow aluminum salt, titanium dioxide, talc and indigo carmine aluminum salts.
- The solution "Thioctacid BV" 600. Instructions for use reports that this form of the drug is intended for intravenous injection. The clear solution is yellow and is available in dark glass ampoules. Its active ingredient is also thioctic acid. As additional substances, purified water and trometamol are used.
Pharmacology
What is the medication "Thioctacid BV 600"? Instructions for use, reviews of doctors say that this is a metabolic agent.
In the human body, thioctic acid acts as a coenzyme, which is involved in the oxidative reactions of phosphorylation of alpha-keto acids, as well as pyruvic acid. In addition, it is an endogenous antioxidant. By its principle of action (biochemical), this component is as close as possible to B vitamins.
According to experts, thioctic acid protects cells from the toxic effects of free radicals that are formed during the metabolism. It also helps to neutralize exogenous toxic compounds that have penetrated the human body.
Drug properties
What are the properties of the drug "Thioctacid BV 600? Instructions for use report that thioctic acid is able to increase the concentration of such an endogenous antioxidant as glutathione. A similar effect leads to a significant reduction in the severity of signs of polyneuropathy.
It cannot be said that the drug in question has a hypoglycemic, hepatoprotective, hypocholesterolemic and hypolipidemic effect. He is also able to improve trophic neurons.
The synergistic effects of thioctic acid and insulin increase glucose utilization.
Pharmacokinetics
What kinetic features does the medicine “Thioctacid T” (100 and 600) have? Instructions for use indicate that the absorption of the active substance of this medication occurs quickly and completely.
Simultaneous eating can significantly reduce the absorption of the drug. Its highest concentration in the blood is achieved approximately 35 minutes after ingestion. The absolute bioavailability of thioctic acid is about 20%.
The medication in question is metabolized in the liver, and excreted in the urine.
Indications
In what cases is a drug such as Thioctacid BV 600 prescribed? Instructions for use indicate the following indications for use:
- polyneuropathy caused by alcohol;
- diabetic sensory-motor polyneuropathy.
Contraindications
Due to the lack of sufficient experience with the use of this tool and clinical studies, it is highly recommended not to appoint it to nursing mothers and pregnant women.
Is it possible to give a child the drug "Thioctacid 600BV"? The use of this medicine in children and adolescents is prohibited. Also, it should not be used in case of an allergic reaction to any of the components.
The drug "Thioctacid BV 600: instructions for use
Use this medication only as directed by the therapist. Tablets must be taken in its entirety, on an empty stomach (for example, 40 minutes before breakfast).
As a rule, Thioctacid BV (600 mg) is prescribed to patients in the amount of one tablet once a day.
As for intravenous administration, this procedure is carried out very slowly (50 mg per minute).
The initial daily dose of the drug in question is 600 mg. After 4 weeks, the indicated amount can be reduced by half.
It is forbidden to leave ampoules with a medicinal substance in the light.
Adverse reactions
With internal administration of the drug, the patient may develop such undesirable effects as:
- allergic reactions in the form of rashes and itching on the skin, as well as urticaria;
- side effects from the digestive tract (diarrhea, nausea, pain and vomiting).
As for the injectable form, it often causes:
- skin rash, anaphylactic shock, and itching;
- difficulty breathing and a sharp increase in pressure (intracranial);
- bleeding, cramps, vision problems, and minor hemorrhages.
Cases of drug overdose
If the recommended doses of the drug are exceeded, the patient may develop symptoms such as convulsions, lactic acidosis, bleeding disorders and hypoglycemic coma.
When observing such reactions, you should consult a doctor, and also induce vomiting in the victim, give him enterosorbents and rinse your stomach. The patient should also be supported until the ambulance arrives.
Drug interaction
According to the instructions, the drug "Thioctacid BV" should be combined with extreme caution with "Cisplatin", metal-containing agents, insulin and drugs for diabetes. It is also not recommended to take it together with alcohol due to a possible decrease in the effectiveness of the drug.
The interval between doses of magnesium or iron and Thioctacid BV should be 7 hours.
Analogs and cost
Replace a drug such as Thioctacid BV with the following drugs: Berlition, Alpha Lipon, Dialipon, Tiogamma.
As for the price, it can be different for different forms and manufacturers. The cost of the tablet form of "Thioctacid BV" (600 mg) is about 1700 rubles per 30 pieces. A medicine in the form of a solution can be purchased for 1,500 rubles (for 5 pieces).
Reviews about the drug
As you know, the drug "Thioctacid BV" is intended for people who suffer from severe metabolic disorders. Reviews of patients about the tablet form are ambiguous. According to their reports, this tool is very effective. But unfortunately, tablets often cause adverse reactions, which manifest themselves in the form of nausea, urticaria, and sometimes even in the form of hot flashes and changes in the patient’s well-being and mood.
Now you know what the medicine “Thioctacid BV 600” represents. Instructions for use, the price of this medicine has been described above.
Reviews about the mentioned remedy leave not only those patients who take its tablet form, but also those who have been prescribed a solution for injection.
According to reports of such people, side effects with intravenous administration of the drug are much less common. Moreover, they are not as pronounced as when taking pills.
Thus, it can be safely noted that “Thioctacid BV” is a very effective tool designed to combat the signs of polyneuropathy that arose after a long intake of alcoholic beverages or against the background of diabetes mellitus.