Means "Nolitsin" is an antibiotic-antiseptic. The drug is active against gram-negative aerobes and a number of gram-positive bacteria. The active substance is norfloxacin.
After penetration, the drug undergoes rapid absorption from the digestive tract. The drug reaches its maximum concentration after an hour or two. The bioavailability of the drug is about 30-40%. Within two days of use, a stable concentration of the drug is achieved.
The active substance is fairly well distributed in tissues and fluids. About eighty percent is excreted unchanged in the urine. The half-life of the drug is carried out for three to four hours.
Means "Nolitsin" (reviews of experts confirm this) is effective for chronic and acute infectious lesions in the urinary tract, provoked by microorganisms that are sensitive. Indications include gonorrhea, chronic prostatitis of a bacterial nature, bacterial gastroenteritis.
The medicine "Nolitsin" (reviews of doctors testify to this) should also be used as a prophylaxis not only for infectious lesions in the urinary tract, but also for "traveler's diarrhea", as well as for selective decontamination of the gastrointestinal tract in patients with impaired immune system activity.
Nolitsin tablets (reviews of doctors confirm this) must be taken during or before meals. Drink should be a sufficient amount of liquid.
The drug is recommended to be taken in a dosage of four hundred milligrams twice a day.
In acute cystitis in women, the duration of treatment is from three days to a week. With a relapse of cystitis, treatment is carried out for a week or two.
In acute uncomplicated pyelonephritis in women, the recommended duration of administration is seven to fourteen days.
Men with acute infections in the lower urinary tract are prescribed treatment lasting from seven to fourteen days.
In chronic bacterial prostatitis, the duration of taking the drug "Nolitsin" (reviews of experts confirm this) can be from four to six weeks.
With gonorrhea, the drug is taken for three to seven days.
With bacterial gastroenteritis, treatment lasts up to five days.
As a prophylaxis of recurrent infectious lesions in the urinary tract, Nolitsin is prescribed at a dose of 200 milligrams once a day. The course lasts six months for several years.
With "traveler's diarrhea," four hundred milligrams is prescribed once a day. The application should be started a day before the trip. Continue taking the drug "Nolitsin" throughout the trip and for another two days after returning. In general, the duration of use should not exceed three weeks.
In sepsis, patients with neutropenia are prescribed 400 milligrams twice a day. Duration of use is up to eight weeks.
Taking the drug "Nolitsin" can cause diarrhea, appetite, nausea. A medication can also provoke dizziness, headache, allergies. In elderly patients, disorders of the central nervous system can occur, manifested by increased fatigue, drowsiness, irritability, bouts of fear, depression, anxiety, hallucinations, and more.
When using the drug "Nolitsin", tendonitis or tears in the tendons may occur. This phenomenon is rare. However, when the first signs of inflammation in the tendons appear, consult a doctor. As a rule, in these cases, the use of the drug is canceled.
The drug "Nolitsin" analogues has the following: "Levofloxacin", "Norfloxacin" and others.