Before selecting analogues of "Meronem", it is necessary to study the features of this drug, the indications and contraindications for its use. This is an antibiotic that affects infections of a bacterial origin of an aerobic and anaerobic nature.
The effect of the use of the antibiotic is achieved thanks to the main component, which freely penetrates the structure of bacteria and blocks the synthesis processes in pathogens.
Features of the drug
The medicine "Meronem" refers to good antibacterial agents. It has an effective bactericidal effect, as it affects the synthesis of bacterial cells. The high level of activity of the main active substance in relation to a wide range of aerobic and anaerobic infections is explained by the ability to penetrate the cell structure.
The drug can be used as an independent drug, or in combination with other drugs to enhance their therapeutic effect. Metabolism occurs in the liver. The drug "Meronem" penetrates quite well into almost all body tissues, which contributes to faster and more active treatment.
The elimination period of the drug is 1-1.5 hours, and in the urine the active substance can be detected for another 12 hours. Elderly people and those suffering from renal failure require individual dosage adjustment of the drug. People with liver failure do not need a dosage adjustment.
Composition and form of release
A medicine is produced in the form of a powder intended for the manufacture of an injection solution of 500 and 1000 mg in a vial. The package contains 10 bottles. The active substance is Meronem, and other components are also included.
The manufacturer of Meronem is the Japanese company Dainippon Sumitomo Pharmaceuticals Company. The medicine fully meets all quality and safety standards.
Indications for use
The use of Meronem is indicated for the treatment of diseases provoked by pathogens that are sensitive to this drug. These include:
- sepsis;
- genitourinary tract inflammation;
- pneumonia;
- inflammation of the abdominal cavity;
- meningitis;
- inflammatory processes of the skin and soft tissues.
Also, the use of "Meronem" is justified at febrile temperature, and low immunity. In this case, the medication is used for self-treatment and in combination with antiviral and antifungal drugs.
Application features
According to the instructions for use, the Meronem antibiotic for adults is prescribed depending on the condition of the patient, as well as the type and severity of the course of the disease. To eliminate infections of the skin, urinary tract, endometritis, as well as pneumonia, injections of the drug are prescribed every 8 hours, 500 mg intravenously. You can also enter "Meronem" intramuscularly. In this case, the dosage and course of treatment is determined by the doctor.
According to the Meronem instructions, 1 g is prescribed every 8 hours for the treatment of peritonitis, septicemia, and pneumonia. During the treatment of meningitis, it is recommended to use 2 g each. This dosage of Meronem has not been studied well enough.
When using the drug, elderly patients do not need to adjust the dose and duration of therapy, however, only on condition that they do not suffer from liver and kidney diseases.
Intravenous administration of Meronem is shown to children from 3 months to 12 years. The dose is 10-20 mg / kg. The medicine must be administered every 8 hours, depending on the type of infection and the severity of the inflammatory process. Also taken into account is the patient's condition and the sensitivity of pathogens. Children weighing more than 50 kg are prescribed a dosage for adults. In the treatment of meningitis, the drug must be administered every 8 hours. The dose of Meronem is 40 mg / kg.
With intravenous injection, the drug should be administered for at least 5 minutes. You can also use a dropper, in which case, the duration of administration of the drug is 15-30 minutes. To dilute it, you need to use appropriate infusion fluids.
The concentration of the solution should be 50 mg per ml. It retains its stability for 16 hours after its preparation. You must adhere to the rules of preparation, as well as shake the bottle just before the procedure. It is recommended to use the Meronem drug for 5-15 days.
Contraindications and side effects
According to the instructions, Meronem is prohibited to use in the following cases:
- children under 3 months;
- when the body is sensitive to antibacterial drugs;
- with intolerance to the components of the drug;
- gastrointestinal diseases and colitis;
- pregnancy and lactation.
Adverse events following the use of this drug are infrequent. There is information about such consequences as:
- abdominal pain, nausea, stool disturbance;
- itching, rashes on the skin;
- anemia;
- cramps, headache;
- hypertension, tachycardia;
- allergy;
- inflammatory processes in the field of drug administration;
- depression, insomnia, hallucinations.
According to the reference book of medicines or radar, "Meronem" refers to a group of antibacterial drugs. It helps to cope with many pathogens. However, during its application, the possibility of an overdose is not excluded. This mainly applies to patients who have impaired renal function. In this case, a hemodialysis procedure and symptomatic treatment are prescribed.
special instructions
According to the instructions, the antibiotic Meronem is used in the treatment of many diseases of an infectious nature. If there is a suspicion of an infection in the respiratory organs, it is recommended to conduct a sensitivity test. This also applies to patients who are in critical condition and are taking the drug in monotherapy.
Very rarely, when taking this remedy, colitis is observed. Its forms and manifestations can range from lungs to those that carry a danger to life. In the event of colitis, you need to refuse to take an antibiotic. It is also important to be careful when taking this medication for people who have spasms periodically.
Sometimes patients complain of hypersensitivity from the drug and the appearance of allergies. When the first signs of an allergic reaction appear, you need to stop taking "Meronem" and conduct appropriate treatment. Use of the drug in people with impaired liver function requires constant monitoring of bilirubin levels.
The use of the drug during pregnancy has not been studied. Those studies that have been conducted on animals have shown that Meronem in a newborn does not cause any adverse effects. However, it is still not recommended to use the medicine while carrying the baby, except for those cases when its benefit to the woman significantly exceeds the probable risk to the fetus. In any case, the therapy is carried out under strict medical supervision. If you exceed the dosage, there is a risk of spontaneous abortion.
In the period of a lactation it is not recommended to accept "Meronem" as it was noticed that it is removed together with breast milk. That is why you need to either cancel the antibiotic or stop lactation.
It is worth considering the possibility of manifestation of dangerous consequences when using Meronem simultaneously with drugs that have a toxic toxic effect on the kidneys. In addition, this medicine lowers the level of valproic acid. Meronem refers to prescription antibiotics. Shelf life is 4 years, subject to storage rules.
Analogues of the drug
Before using Meronem analogues, the instructions for use, indications and contraindications must be studied to prevent the occurrence of side effects. There are many drugs with a similar spectrum of action and the following are considered the main ones:
- "Meropenem";
- "Merogram";
- "Invasion."
Choosing analogues of Meronem, it is worth paying attention to the drug Meropenem. It is produced in the form of a crystalline powder intended for the manufacture of an injection solution. Another good remedy is considered to be "Invasion." It helps to actively combat many pathogens, however, it is worth remembering that it is forbidden to use it to treat children under 18 years of age.
The drug "Merogram" is available in the form of a powder intended for the preparation of injections. It is tolerated much more easily than Meronem, and also causes much less allergic reactions.
The drug "Meropenem"
The analogue of Meronem is the drug Meropenem, which refers to antibiotics of the carbapenem group and is used to treat various infectious and inflammatory processes provoked by sensitive pathogens. It demonstrates a good result in the fight against many pathogens, so it can be used without bacteriological research.
This medicine has pronounced antibacterial and bactericidal properties, so it can be used to treat infectious lesions of the genitourinary system.
The antibiotic is available in powder form, which is used to prepare a therapeutic solution. It is packaged in 10 ml clear glass bottles. The drug is used for:
- abdominal infections;
- pneumonia
- gynecological infectious diseases;
- purulent skin lesions;
- sepsis
- inflammation of the membranes of the brain;
- suspected bacterial infection.
The drug is administered intravenously or intramuscularly very slowly. First, the contents of the vial must be diluted with 15 ml of water for injection. If necessary, infusion, the drug is mixed with 50-200 ml of the base. The dosage depends on the type of disease. The duration of the therapeutic course is determined separately for each patient and generally is 7-14 days.
The drug is not used if there is an individual intolerance to the components of this drug. A side effect is a deterioration in well-being, a decrease in appetite, as well as the appearance of thrombophlebitis. It is not recommended to use the drug during gestation and lactation. Antibiotics can be used to treat infectious processes in children older than 3 months.
The drug "Invasion"
A good analogue to Meronem is considered to be the medicine "Invanz." This is an antibiotic that is used to treat pneumonia, bacterial infections of the gastrointestinal tract, urinary system, and skin. In addition, it is used in the postoperative period.
The drug is administered intramuscularly or intravenously. The doctor selects the dosage and regimen strictly individually. A contraindication to its administration is individual intolerance to the components of the drug. It is also not recommended to use it during pregnancy and lactation.
Adults and children from 12 years of age are prescribed 1 g per day. You can use the medicine in the form of intravenous infusion, as well as intramuscular injection. In the case of a dropper, the duration of administration of the drug should be at least 30 minutes. Intramuscular injections are used if necessary or in the absence of the possibility of intravenous administration. The duration of the therapeutic course is from 3 days to 2 weeks. If you feel better, you can switch to the oral form of taking antibacterial agents.
In case of impaired renal function, a correction of the daily dosage of the Invans preparation is required. It is forbidden to mix the medicine or administer it simultaneously with other active substances. Side effects rarely occur, they include diarrhea, headache, nausea, venous disturbances. Allergies are also possible. If it occurs, you need to cancel the use of the drug and consult a doctor for urgent treatment.
During pregnancy, it is allowed to use this medication only if the benefit exceeds the likely risk to the fetus. Due to possible adverse reactions in the newborn, the use of the drug during lactation is not recommended.
The drug "Cironem"
To choose the analogue of "Meronem", the instructions for using the medicine must be carefully studied. In addition, the consultation of the attending physician is required, since only in this way can the desired result be achieved and the occurrence of complications can be prevented.
Good analogues include the drug "Cyronem", which is intended for the treatment of pneumonia, infection of the abdominal cavity, pelvic organs, urinary tract, soft tissues. In addition, you can use the medicine to treat bronchitis.
The drug is available in the form of a powder intended for the preparation of an injection solution. After administration, the drug penetrates well into the tissues and spreads throughout the body. During pregnancy and lactation, treatment with this agent can only be carried out if the benefit to the mother outweighs the risks to the fetus. Among the side effects, it should be noted such as:
- nausea, diarrhea, vomiting;
- allergy;
- headache;
- local reactions.
When treating patients with liver disease, it is important to periodically test for bilirubin levels. In the case of monotherapy or suspected infection of the lower respiratory tract, it is necessary to regularly test the sensitivity of the pathogen. With caution, use the medicine as part of a combination treatment with drugs that have a toxic effect on the kidneys.
The drug "Propinem"
This is an antibiotic of the carbapenem group. It exerts its bactericidal effect due to a violation of the structure of bacteria. The drug is active against most pathogens. Some strains of staphylococcus, enterococcus are resistant to the main substance of the drug.
The drug is used for intravenous and intramuscular administration, and quickly spreads throughout the body. Well suited for the treatment of infectious diseases provoked by bacteria. Before using the medicine, you need to consult a doctor, as well as undergo a mandatory examination of the body to make sure that there are no contraindications to its use.
During pregnancy and lactation, the use of the drug is only possible if the expected benefit of the therapy for the mother significantly exceeds the risks to the fetus. Among the contraindications, it is necessary to highlight an increased sensitivity to the main components of the drug. In some cases, side effects may be observed, which include:
- abdominal pain, nausea and vomiting;
- increased bilirubin;
- the appearance of allergies;
- rashes, skin itching;
- headache, cramps.
In addition, thrombophlebitis, as well as pain and inflammation at the injection site, may develop at the injection site.
With intravenous administration, a single dosage for adults is from 500 mg to 2 g, and the frequency and duration of the drug is determined individually, depending on the indications and the severity of the course of the disease. Children weighing less than 50 kg are prescribed 10-12 mg / kg. The drug is applied every 8 hours. For children weighing more than 50 kg, the dosage is prescribed exactly the same as for adults.
When administered intramuscularly, it is indicated to use 500 mg every 8 hours, and for older people - 500 mg every 12 hours. In case of an overdose, an increase in symptoms of a side effect is observed. In this case, symptomatic therapy is required. Sometimes hemodialysis may be necessary.
The drug "Janem"
It is prescribed for infectious diseases provoked by bacteria. These include such as:
- pyelonephritis;
- peritonitis;
- endometritis;
- dermatosis;
- pneumonia;
- meningitis.
It is forbidden to use the drug for the treatment of infants under the age of 3 months. Also a contraindication is intolerance to the components of the drug. During pregnancy, it is not recommended to use this medicine for therapy. However, in some cases, it is still prescribed, namely, if the likely benefit to the mother significantly exceeds the risk of complications in the fetus. Therapy is carried out strictly under the supervision of a doctor. During therapy with this drug, you should definitely stop breastfeeding.
In some cases, side effects are observed, which after a while pass. If the patient is in a serious condition, symptomatic therapy may be required. When taking the drug "Dzhenem" may be fainting, depression, hallucinations, insomnia, as well as many other negative manifestations.
Treatment of patients with liver problems should be carried out strictly under the supervision of a doctor, and constant monitoring of bilirubin in the blood is required. In the process of therapy, the development of resistance of pathogens to the active component of the drug is possible. .
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