In the article, we consider the instructions for use, reviews and analogues to the drug "Furagin".
It is an antimicrobial drug derived from nitrofuran. It is active in relation to many gram-positive or gram-negative microbes, pathogens and microorganisms having resistance to antibiotic drugs. Reviews about "Furagin" are abundant.
Structure
The active component in the composition of the drug is furazidine. As auxiliary substances used: polysorbate, calcium stearate, povidone, crospovidone, corn starch, microcrystalline cellulose, lactose.
Pharmacological forms
The manufacturer produces the drug in tablet form. The tablets are small in size, yellow in color and flat-cylindrical in shape. Packed in blisters for 10 pieces. Each box can accommodate 3 blisters.
The drug has antimicrobial properties and has a wide range of effects.
This is confirmed by the instruction to "Furagin". Reviews about him are mostly positive.
Pharmacokinetics, pharmacodynamics
The drug is able to affect most gram-negative and gram-positive microorganisms. Its therapeutic effect is due to its affiliation with nitrofuran and the fact that it contains a compound capable of binding to the active substances of a pathogenic cell that transfers hydrogen molecules. As a result, the subsequent activity of the microbial cell stops.
A positive result occurs when taking the active substance in small concentrations.
Absorption occurs in the intestine as a result of passive diffusion. After ingestion, furazilin disinfects the bladder, urethra, kidneys. Evacuation is carried out by the kidneys.
Thus, the medication is not a systemic antibiotic, since it has a local effect, it is an antimicrobial and antibacterial medication.
Reviews on the use of "Furagin" consider below.
Indications
The main indications for the use of the drug are:
- Prevention of infectious processes in the treatment of recurrent pathologies.
- Diseases of the genitourinary system that are inflammatory and infectious.
Quite often, the drug is prescribed to patients after surgery, with urethritis, pyelonephritis, prostatitis, cystitis.
There is also another form of the drug called Furagin Lect, which has an antimicrobial effect and a wide range of effects. It is prescribed in the following situations:
- Infected wounds.
- Severe burns that have been infected.
- Diseases localized in the pharynx and oral cavity and having an inflammatory and infectious nature.
- Prevention during urological operations.
- Urogenital infectious lesions.
- Infection of soft tissues, skin integument.
According to reviews, "Furagin" with cystitis quickly helps.
Contraindications
First of all, you should not use the medicine for the treatment of cystitis if the patient has renal failure or hypersensitivity to any component that is part of it.
The use of Furagin is not recommended:
- With congenital enzymatic deficiency of glucose-6-phosphate dehydrogenase.
- Under the age of 7 days.
- If you are allergic to nitrofuran derivatives.
- In the presence of multiple lesions of the nerves of the peripheral NS.
- In the lactation period.
- During pregnancy.
Negative impact
Against the background of the use of "Furagin", according to reviews, the following negative reactions may develop:
- Multiple nerve damage of peripheral NS, drowsiness, visual impairment, neuritis, dizziness.
- Rash, itchy skin.
- Nausea, abdominal pain, upset stools, vomiting, decreased appetite.
In rare cases, patients note the development of chills, fever, malaise.
Using
Patients are prescribed the drug only after eating. In this case, the recommended dosages should be observed, most often they are as follows:
- Children with conventional treatment are shown to take up to 7 mg / kg once a day, if therapy is long - up to 2 mg / kg.
- In order to prevent diseases of infectious and inflammatory genesis, it is indicated in the evening to take one tablet.
- In the treatment of adult patients, four tablets are prescribed four times a day, then the dosage is left unchanged, and the frequency of doses is reduced to three.
Throughout the entire course of therapy with Furagin, experts recommend adhering to a protein diet.
The duration of the course does not depend on the disease for which the use of the medication is directed. Its duration is usually up to 10 days. If necessary, therapy for cystitis or other infectious and inflammatory pathologies can be extended up to 15 days.
If Furagin is used for a long period of time, the patient should monitor the renal and hepatic functionality, the level of leukocytes.
When using Furagin Lect, adult patients are prescribed oral administration of up to 100 mg of the drug three times a day, for children over 3 years old - up to 50 mg with the same frequency of doses. Therapy with this medication involves its use for up to 10 days. If necessary and at the discretion of the doctor, the course of therapy can be repeated after two weeks.
For prophylactic purposes, take 50 mg of medication once before the procedure.
It is allowed to use Furagin for the purpose of wetting dressings or washing infected wounds, as well as for rinsing the throat and mouth. Procedures must be carried out three times a day.
Overdose
When taking excessively large doses of the drug, the development of an overdose is not ruled out, expressed in the appearance of the following symptoms:
- Violation of the liver.
- Nausea.
- Bronchospasm, urticaria, angioedema and other allergic reactions.
- Deterioration of mood, psychosis, inflammation of the nerves of peripheral NS and other disorders of the central nervous system.
To eliminate the unpleasant and sometimes dangerous symptoms of an overdose, the patient is shown to undergo gastric lavage drug therapy. If a severe overdose occurs, hemodialysis is used.
It is better to familiarize yourself with the reviews about Furagin tablets in advance.
Interaction with other medicines
The effectiveness of the drug is significantly reduced, and its concentration in the blood increases, when combined with drugs based on nadlidiksovoy acid and drugs that can increase the level of uric acid in the urine.
When used concurrently with medicines that lower the acidity of gastric juice and incorporate magnesium trilixade, a pronounced decrease in the absorption of the drug is not ruled out.
Below are reviews and analogues of "Furagin."
Analogs
If necessary, the drug can be replaced by "Furamag" or "Furaxol", however, the feasibility of such a replacement should be agreed with a specialist.
The most popular analogue is Furamag, which is based on basic magnesium carbonate and potassium furazidine.
The main difference between Furamag and the drug under consideration is its higher bioavailability, while the maximum saturation of the blood with the active component when taking Furamag lasts longer. Thus, the bacteriostatic effect is higher for Furamag.
Therapy for children "Furagin"
Pediatric patients suffer from infectious lesions of the urine excretion system quite often, and infections that are not completely treated before the end begin to recur. In order to avoid such situations, it is necessary to take appropriate medications. Most often, with recurrent infectious diseases in children, experts recommend taking antibiotic drugs. If these funds are not suitable for therapy, then the child is prescribed "Furagin." In comparison with many antibiotics, addiction to “Furagin” does not develop.
In addition, the drug combines well with other medications, is well tolerated by children, and can be used not only for treatment, but also for prevention.
It is unacceptable to prescribe medication for children up to a month, it is important to exercise caution when using the medication in children under 3 years of age.
The dosage of the medicine should be calculated by the pediatrician based on the weight of the small patient. Use up to 7 mg / kg is indicated. In the treatment of children, the tablets are pre-ground into powder and mixed with a liquid. It can be either water, or milk or a mixture. With prolonged therapy, the pediatrician should adjust the dose and reduce it to 2 mg / kg.
So it is said in the instructions for use for "Furagin". Reviews on the use of the drug for children are also available - positive and in large quantities.
Use in the lactation period and during pregnancy
The use of "Furagin" in the lactation period and at all stages of pregnancy is completely contraindicated. If it becomes necessary to use the drug by a nursing woman, breastfeeding should be temporarily suspended, and the resumption of natural feeding is allowed only after the active substance leaves the body.
Cost
The average cost of Furagin in Russian drugstores is 200 rubles. It depends on the region and the pharmacy network. The drug has one of the lowest prices in comparison with its counterparts.
Reviews about "Furagin"
Reviews about the experience of using the drug for the treatment of cystitis and other pathologies of the genitourinary system that have an infectious and inflammatory genesis are rather contradictory. Some patients note the effectiveness of the drug, others report a complete lack of therapeutic effect. Very often there is information that the medication provokes the development of negative reactions, but positive reviews are even more common.
Reviews about "Furagin" for children are mostly positive. Nevertheless, it is important to remember that the appointment of therapy and the necessary medications should be carried out by the doctor.