Diseases associated with severe skin damage are a real test for people. In these situations, glucocorticosteroid drugs, such as Cloveit ointment, are prescribed. Hormonal or not - this is what worries patients using it in treatment. Yes, it is hormonal and addictive, but, despite this, it works effectively even in the most serious situations. The tool is quite strong. It can only be used as prescribed by the doctor in the case when weaker drugs do not help.
Cloveit ointment: composition, release form
The drug refers to glucocorticosteroids used topically. It is produced in the form of a white translucent substance. Cloveit ointment in one gram contains 500 micrograms of clobetasol propionate. Additional components in its composition are propylene glycol in an amount of 50 mg, sorbitan sesquioleate in a dose of 5 mg, white petrolatum in a volume of 1 g is added here.
The product is produced in aluminum tubes of 25 g. Each tube is packed in a cardboard box and has instructions for use.
In order for the medicine not to lose its therapeutic properties, it should be stored at a temperature not exceeding 25 ° C. The ointment should not be frozen. The shelf life of the drug is three years.
The manufacturer is the Polish company Pharmaceutical Plant Elfa JSC. The official representative is located in Moscow.
pharmachologic effect
Cloveit ointment refers to glucocorticosteroids and is used only locally. Prevents the accumulation of neutrophils. Reduces inflammatory exudation, as well as the release of lymphokines. Slows down the movement of macrophages. Reduces the severity of the formation of infiltration and granulation. The drug has a pronounced local antipruritic, antiexudative, anti-inflammatory, anti-allergic effect.
Suction. The average maximum concentration of the active substance in the blood is 0.63 ng / ml. Such a plasma level appears after thirteen hours after the initial application and eight hours after repeated application of the medicine to a healthy dermis. Three hours after a single application of the drug in patients with eczema and psoriasis, the maximum concentration of clobetasol propionate is 4.6 ng / ml and 2.3 ng / ml, respectively.
If the medicine is applied to large areas of the skin, then its absorption is possible. The presence of damage to the epidermis and the inflammatory process on the skin increases absorption. Such a picture can provoke the appearance of a systemic effect.
The drug is broken down mainly by the liver, only a small part of it is excreted in the urine.
Indications for application
Cloveit ointment is prescribed for medicinal purposes in acute non-infected dry diseases in a severe stage of development. The drug is used for inflammatory skin diseases that respond to glucocorticosteroid therapy, where itching, excessive keratosis are observed, and when treatment with weaker drugs of this effect does not give the desired effect.
Cloveit ointment is recommended for dermatitis of seborrheic, atopic and contact type. It is recommended to use the medicine for psoriasis, erythematous and lichen planus. Prescribe the drug for erythema multiforme and lupus erythematosus discoid type. An ointment is recommended for various forms of eczema.
Contraindications
Cloveit (ointment) is a serious hormonal drug that should only be prescribed by a doctor. The use of this drug has a number of contraindications, it is rosacea and acne vulgaris, skin cancer. The prohibition is Hyde's nodular pruritus . Do not use the medicine for perioral dermatitis, as well as for itching of perianal and genital nature. Not recommended for the treatment of skin rashes with syphilis and liver rash. You can not use "Cloveit" if there are fungal, bacterial and viral lesions of the epidermis. Contraindication is plaque and pustular psoriasis with a wide area of distribution.
Do not prescribe the drug to children under one year of age, as well as pregnant and lactating women and people suffering from hypersensitivity to the substances in the ointment.
Cloveit (ointment): instructions for use
The drug is used only externally. Cloveit ointment (instructions for applying the medicine should be studied) is applied a thin layer to the problem area once or twice a day. The therapeutic course does not exceed four weeks.
In especially difficult situations, when there is hyperkeratosis and not only, the effectiveness of the drug is increased by applying a compress with ointment from a plastic film overnight. Such use of the drug, as a rule, gives a positive result. Before applying a new occlusive dressing, the skin should be thoroughly cleaned. After a certain time, the achieved effect can be maintained without a compress.
The occurrence of acute overdose is almost impossible. With improper use, signs of hypercorticism may appear , if they occur, the medicine must be discontinued.
Side effects
With prolonged treatment with ointment, negative phenomena can be observed: burning of the skin, itching, acne of a steroid nature, excessive dryness of the epidermis. As a result of prolonged use, a decrease in the protective barrier of the skin is observed. When applying the ointment in large quantities, when there is a need for occlusive dressings, or when applying the product to a place with folds, atrophic changes in the dermis occur, including thinning of the epidermis, the appearance of striae, superficial venous expansion. In special cases, pigmentation of the skin, hypertrichosis is observed. In the treatment of psoriasis or after discontinuation of the drug, pustular psoriasis may develop.
If the drug is used on a large surface, the following symptoms may occur: gastritis, damage to the mucous membrane of the gastrointestinal tract, increased intraocular pressure, hypercorticism. Children who are given an occlusive dressing are particularly prone to these side effects. The diaper in this case plays a role similar to a bandage.
When prescribing the ointment in a dose exceeding 50 g per week, a temporary weakening of the functioning of the pituitary and adrenal glands may occur, at the end of the course of treatment, these symptoms disappear. In exceptional situations, the medicine causes an exacerbation of the disease.
special instructions
Cloveve ointment is prescribed by doctors for the treatment of skin lesions in which excessive dryness of the dermis, thickening or hyperkeratosis occurs.
The drug is addictive and therefore suitable only for short-term therapy. You should not use a glucocorticosteroid for a long time, especially for children, since in this case there is a chance of suppressing adrenal function. When treating with this remedy, babies need constant monitoring by a specialist at least once a week.
The skin on the face is more susceptible to atrophic changes than on the rest of the body, especially as a result of prolonged use of the ointment.
Do not apply the medicine to the eye area, as this can affect the occurrence of glaucoma.
In the treatment of psoriasis with glucocorticosteroids, a relapse of the disease, a generalized pustular form, drug tolerance, the development of external or systemic reactions of toxic origin can be observed. During the treatment with this drug, it is important that the doctor controls the situation.
If the disease is accompanied by a secondary infection, then the therapy is supplemented with antibacterial drugs. If the infection has generalized, then treatment with ointment should be stopped and antibiotic therapy should be carried out. A moist and warm environment created by an occlusive dressing creates favorable conditions for the penetration and development of a bacterial infection. Therefore, it is necessary to clean the epidermis before using a new compress.
The drug does not affect the concentration of attention and the speed of response of the patient.
Analogs
If for some reason the drug “Cloveit” (ointment) did not fit, analogues can always replace it. An alternative medication should be selected by the doctor, based on the full picture of the disease.
To analogues having the same active substance as that of Cloveit, clobetasol, it should be attributed:
- "Dekloban";
- Powercourt;
- Dermoveit;
- "Karizon";
- "Clobetasol."
All drugs are approximately equal in their effect, but Cloveit ointment is cheaper than analogues.
Cost
The drug "Cloveit" is sold only in pharmacies and dispensed exclusively by prescription. Its average price fluctuates around 200-250 rubles.
Patient reviews about ointment
They say that gives a quick and effective result ointment "Cloveit" reviews. Patients claim that the ointment improves the condition of the skin with psoriasis and eczema. It gives a positive result with allergic dermatitis. Removes all severe lesions of the epidermis in a short time. Many patients like that the ointment does not smell, is inexpensive and quickly absorbed, leaving no residue. It softens rough skin areas. For some people, this drug is a real salvation, since it heals painful ulcers, wounds on the hands that were formed due to excessively dry skin with dermatitis and eczema.
Some are very careful about this tool. It is noted that it contains a strong hormone and can not be used without a doctor’s prescription. It is claimed that the drug can cause a side effect in the form of a rash. It is advised to think several times before using this ointment.
Despite the fact that the reviews about the drug vary, there are no patients to whom the medicine did not help. An exception are cases when the ointment was used for other purposes and without a doctor's prescription.