Means "Flixonase" - a drug for topical use. In pharmacies, it is dispensed at a price of 729 rubles per package. It contains micronized fluticasone propionate, as well as excipients.
Pharmacokinetics
Means "Flixonase" is slightly soluble in water, therefore, has a low absorption with the mucous membrane of the nasal passage. As a result, most of it is swallowed. Up to 1% of a single dose of the substance is absorbed into the systemic circulation. This is the reason for the low total absorption of the drug from the nasal cavity and digestive system. 91% of the active substance binds to plasma proteins. The drug "Flixonase" is excreted through the liver during metabolism with bile. The drug is available in the form of a nasal spray, 60 doses per bottle.
What is the equivalent of Flixonase?
The price of the drug, it should be said, is relatively high. Therefore, many are looking for ways to replace the medicine, while spending less money. Medications are prescribed as a prophylaxis and treatment of allergic rhinitis (year-round, seasonal). Before using any product, a more detailed description of which will be given below, shake the bottle. When opening new
If the treatment is interrupted for longer than a week, the nebulizer must be checked. To do this, click on it, after sending it from you. Before using the product, you should clean your nose, then insert the tip of the bottle into one nostril, closing the other in advance. After that, perform a single press to spray the substance, inhaling through the nose. At the end, exhale through the mouth. Next, repeat the procedure from the second nostril. After using the medication, blot the tip of the vial with a tissue. At least once a week, clean the tip under warm water by removing it from the bottle, then dry and put it back on.
Dosage
For patients 4-12 years old, the drug is prescribed at 50 mcg in each nasal cavity once a day. The permissible daily dose is 200 mcg. Patients from 12 years old are recommended 100 mcg in each nasal passage once a day. After reducing the exacerbation of the disease, the dose can be reduced to 50 mcg. With severe symptoms, it is possible to increase the dose of the drug to 400 mcg per day. After a short time after removing the exacerbation, the dose can be reduced. The effect of the drug becomes maximum on the 3-4th day of use. For the greatest effect, it is recommended to take the drug regularly.
Side effect. Contraindications
Analogues of Flixonase, like the medication itself, have various negative consequences. They are expressed in dryness and irritation of the nasopharynx, nosebleeds, skin rash, headache, bronchospasm. Swelling of the face and tongue may occur, an unpleasant aftertaste and smell may appear, nasal congestion, burning sensation. In the case of nasal passages, perforation of the nasal septum is possible . The drug is not recommended for women during pregnancy and lactation, as well as children under 4 years of age.
Nasonex or Flixonase - which is better?
The first drug costs a little more - 790 rubles. But at the same time, m
Legs prefer a more expensive product. In any case, the drugs (Flixonase or Nazonex or other drugs) should be prescribed by the doctor. Self-medication is not allowed in any case. The drug "Nazonex", in addition to anti-allergic, also has an anti-inflammatory effect. The drug is available in the form of a spray with a white suspension. The active component of the agent is mometasone furoate, with additional substances - citric acid monohydrate, dispersed cellulose, sodium citrate dihydride, glycerol,
polysorbate 80, purified water, benzalkonium chloride.
What is safer: "Flixonase" or "Nazonex"?
Contraindications and side effects of the drugs are generally similar. The drug "Nazonex" is not prescribed for tuberculosis, various infections of the nasal mucosa, infections of the fungal, bacterial nature. Its use is not recommended after recently undergone operations and various types of nasal injuries, with individual drug intolerance, pregnancy and lactation. The drug is allowed to be used from an earlier age (from 2 years) than other analogues of Flixonase.
Other medicines
Today, there are various analogues of Flixonase. They have a similar mechanism of action and indications. Quite popular is the Avamis remedy. It is also available in the form of a nasal spray and has a decongestant and anti-edema effect.
inflammatory effect. In pharmacies, it is sold at a price of 505 rubles. The active component of the drug is
fluticasone furoate, 99% of which binds to plasma proteins when used. The drug is excreted mainly with feces, metabolism occurs in the liver. Spray is used only for injection into the nose. Its action begins 7-8 hours after irrigation. To set the correct dosage, shake the bottle before first use and press the dispenser 6 times. The same actions must be done if the spray is not used for more than a month. The agent is used as well as other analogues of "Flixonase" - intranasally. The dosage of the drug depends on the age of the patients. Patients from 12 years of age are prescribed 2 injections once a day. Patients from 6 to 12 years old - 1 irrigation per day.
Conclusion
Analogs of Flixonase, like the drug itself, are similar in their properties and application. There are only slight differences in price, composition, and age categories of patients. However, all the drugs considered direct their action to the fight against anti-allergenic and anti-inflammatory processes. When choosing Avamis or Flixonase, as well as any other medication, you need to consult a specialist.