How to enter "Mexidol" intramuscularly: instructions for use

In the article, we will consider how to administer Mexidol intramuscularly.

Injection solution is a drug related to the pharmacological group of antioxidants. It is used for the treatment of various pathologies of the heart and blood vessels, nervous system, and internal organs.

Many people wonder if Mexidol can be administered intramuscularly. Let's figure it out.

The composition of the drug, pharmacological forms

Mexidol is produced by the manufacturer in the form of a medicinal solution intended for parenteral administration. The product is colorless, transparent, a light yellow color is allowed.

The active substance in its composition is ethylmethylhydroxypyridine succinate. Each milliliter of solution contains 50 mg of the main component. Among the excipients are injectable water, sodium metabisulfate.

The drug solution is packaged in clear glass ampoules having a volume of 2 or 5 ml. How to enter "Mexidol" intramuscularly, described in detail in the instructions.

Additionally, the ampoules are placed in a blister strip packaging of 5 pieces. A cardboard bundle may contain 1, 2, 4, 10, 20 contour packs, accompanied by a manufacturer's annotation.

Pharmacological effects of the drug

How to introduce "Mexidol" intramuscularly, we will describe below.

The active component of the drug solution used for parenteral administration has a number of biological effects, including the following:

1. Anxiolytic effect. Thanks to it, the functional activity of the cerebral cortex of the head improves, the feeling of anxiety, fear decreases.
2. Anticonvulsant effect. The increased pathological impulse in the motor neurons of various structures forming the nervous system is reduced.
3. Nootropic effect. Allows you to protect neurocytes (NS cells) of the damaging effects of various factors with insufficient oxygen supply.
4. Membrane-protective effect. Allows you to protect cell membranes from the damaging effects of various factors, free radicals, which are the remains of organic molecules (in particular, fatty acids), having an unpaired electron and high chemical activity, as well as endogenous toxins (formed in the body against various pathological processes).
5. Antihypoxic effect. Thanks to it, the resistance of cells to insufficient oxygen supply increases.

Due to the presence of these biological effects, a drug solution intended for parenteral administration improves metabolic processes in the cells that make up the nervous system, improves blood rheology, as a result of which its viscosity decreases, and circulation in the microvasculature increases. In addition, following the use of Mexidol, the following effects are observed:

1. Platelet aggregation (gluing) is reduced.
2. The processes of metabolism in the myocardium are normalized with insufficient intake of nutrients and oxygen.
3. Enzyme intoxication decreases when pancreatitis occurs (an inflammatory process in the pancreas).

Everyone should know how to administer Mexidol intramuscularly. At home, the tool is not used.

Similar biological effects of the active substance are realized, it increases the activity of superoxide dismutase, an enzyme responsible for neutralizing free radicals, and reducing the process of peroxidation of fats in cell membranes.

In addition, the drug is able to change the ratio of lipids and proteins in cell membranes. As a result, their fluidity and ductility are improved. It can also modulate some enzymes that are responsible for the state of cell membranes, NS cell receptor complexes, thereby improving the transmission of synaptic nerve signals.

Against the background of the use of parenteral solution, the adaptive abilities of the human body are improved under the influence of a variety of stress factors.

It is very important to find out how many ml inject Mexidol intramuscularly. After administration, the active component begins to accumulate rapidly in the blood plasma and is evenly distributed over all body tissues. The active substance is metabolized in the liver tissue, resulting in the formation of inactive metabolites associated with glucuronic acid. They are excreted together with urine. Some of the ethyl methyl methyl hydroxypyridine succinate is excreted in an unchanged state.

How to enter "Mexidol" intramuscularly? To breed or not? All information can be checked with your doctor.

Indications for the use of the medication

The use of a medicinal solution intended for parenteral administration is indicated with the aim of eliminating the pathological conditions of various organs and their systems:

1. Inflammatory processes of a purulent nature, localized in the abdominal cavity and accompanied by lesions of the peritoneum (connective tissue membrane lining the walls and organs of the abdominal cavity), as well as acute inflammatory processes in the pancreas.
2. Comprehensive treatment of open-angle glaucoma, characterized by increased intraocular pressure and malnutrition of eye retinal neurocytes (dystrophic changes in the eye retina).
3. Myocardial infarction (a pathology in which a part of the heart muscle dies due to acute disorders of its nutrition). In this case, Mexidol is used as an element of complex therapy from the first for treatment.
4. Atherosclerotic lesions of blood vessels located in the brain, accompanied by the formation of cholesterol plaques in them, impaired blood flow, nutrition of brain cell structures, cognitive impairment.
5. Withdrawal syndrome in drug and alcohol addiction. In this case, it is used as an element of a complex effect.
6. Neurosis-like conditions accompanied by neurotic disorders, a sense of fear, anxiety.
7. Vegetative dystonia. It is a pathology of autonomic NS, accompanied by disturbances in the innervation of arteries with fluctuations in the level of systemic blood pressure.
8. Encephalopathy. It is a pathological condition associated with impaired functional activity of the blood vessels that nourish the brain tissue of the head.
9. Postponed TBI, complex therapy of its consequences.
10. Acute forms of circulatory disorders in the brain, accompanied by a sudden decrease in the flow of nutrients and oxygen to neurocytes.

In addition, Mexidol can be used to eliminate the symptoms of intoxication with antipsychotic medications.

Contraindications to the use of a medicinal solution

Injection "Mexidol" is contraindicated if the patient has the following pathological conditions:

1. Increased susceptibility and individual intolerance to any substance that is part of the drug.
2. Renal failure.
3. Lack of hepatic activity.

Before starting therapy with the use of a medication, it is necessary to consult a specialist in order to exclude the presence of contraindications.

How to enter Mexidol?

Parenteral administration of a pharmacological agent should be carried out exclusively in medical institutions, use at home is unacceptable. It must be administered intravenously or intramuscularly, in compliance with the rules of asepsis, antiseptics. This is necessary to prevent infection.

With intravenous use, the medicine should be administered jet, slowly, for 6-7 minutes. In the case of jet administration, dilution with saline is not required. Also, intravenous drip is allowed, while the medicine should first be diluted with saline. A day is allowed to use no more than 1200 mg of the substance.

In order not to raise the question of how to administer Mexidol intramuscularly, step-by-step instructions for injections will be given below:

1. The ampoule with the medicine is wiped with cotton wool. As a disinfectant, you can take alcohol. Then it should be opened.
2. Type Mexidol into the syringe.
3. Treat the injection site with an alcohol wipe.
4. Raise the syringe with the needle up. Squeeze out a small amount of medicine.
5. Confidently insert the needle into the soft tissues of the buttocks at a right angle.
6. Press a little on the syringe and start administering the medicine. To minimize pain, the drug must be administered slowly, for 5-7 minutes.
7. Get a needle and put a cotton wool on the injection site. To make the medicine dissolve faster, massage the injection site for a minute.

If a long course of using Mexidol is expected, then injections are placed alternately in different buttocks.

Dosage

The modes of application and dosage of the drug solution depend on the nature of the pathological process:

1. In case of poisoning with antipsychotic drugs, it is indicated for two weeks to administer 200-250 mg intravenously in a stream and drip.
2. With open-angle glaucoma, intramuscular administration is indicated 1-3 times a day, 100-300 mg each. Therapy takes 2 weeks. How to introduce "Mexidol" 5 ml intramuscularly with alcoholism?
3. In case of withdrawal syndrome and chronic alcoholism, it is recommended to inject the drug twice or three times a day, 200-500 mg intramuscularly or intravenously. The introduction should be carried out for 5-7 days.
4. In case of myocardial infarction, Mexidol should be used as an element of a complex effect together with medicines of other pharmacological agents. During the first 5 days after the onset of myocardial infarction, it is indicated to administer the drug intravenously. After this, it is recommended to switch to intramuscular use and continue therapy for another 9 days. The average dosage is 250 mg, it should be administered with an interval of 8 hours (the dosage for a single injection is calculated based on the patient’s body weight - 2-3 / mg / kg). In this case, the total daily dosage should not be higher than 800 mg.
5. In case of cognitive impairment in elderly patients, with a sense of anxiety, it is recommended to inject 100-300 mg intramuscularly once a day. The duration of therapy is 10-30 days. The fact that Mexidol can be administered intramuscularly is now known.
6. In case of head injury and in order to eliminate the consequences of head injury, 200-500 mg is indicated to be administered intravenously 2-4 times a day. The duration of therapy is 10-15 days.
7. In case of discirculatory encephalopathy, which is at the stage of decompensation, it is indicated to inject 200-500 mg of the substance once or twice a day intravenously. Therapy should last 14 days, after which, in the next 14 days, 100-250 mg of the substance should be administered intramuscularly. For the course prevention of pathology, it is recommended to inject 200-250 mg intramuscularly twice a day. The duration of preventive use is 10-15 days.
8. In acute forms of cerebrovascular accident (with hemorrhagic or ischemic stroke), it is shown 2-4 times a day to inject 200-500 mg intravenously in the first two weeks, after which the dosage should be reduced to 200-250 mg and the therapy should be continued for another two weeks.

How to inject 2 ml of Mexidol intramuscularly with purulent-inflammatory pathologies?

If necessary, treatment of purulent-inflammatory pathologies (necrotic, edematous pancreatitis, peritonitis), the modes of administration and dosage should be calculated taking into account the severity of the pathological process. “Mexidol” should be used in such cases before surgery, after it, until a persistent clinical improvement occurs. In this case, therapy should be discontinued gradually, slowly reducing the dosage.

It is important to determine how to administer Mexidol intramuscularly. At home, it can not be used, since there is a high probability of developing side symptoms.

Negative effects of the drug

Patients usually tolerate Mexidol therapy well. In some cases, nausea, dry mucous membranes in the oral cavity may develop. In addition, allergic responses are not excluded: urticaria, skin itching, rash. The use of high therapeutic doses of the drug can cause drowsiness. If severe negative symptoms occur, the drug should be discontinued and a doctor should be consulted.

To minimize the likelihood of side effects, you should strictly follow the advice and recommendations of a doctor regarding doses and modes of administration.

How to enter "Mexidol" intramuscularly, it is important to find out in advance.

Special instructions for use

It should be borne in mind that the active component of the drug is able to enhance the effect of antiparkinsonian (levodopa), anticonvulsant (carbamazepine) drugs.

During drug therapy, it is not recommended to perform work that requires a quick psychomotor reaction and concentration, so drowsiness may occur as a side effect.

The safety of using the drug for the treatment of children during pregnancy and in the lactation period is not proven, therefore its use is not recommended, but it is possible if the doctor considers that the probable benefit will exceed the risk of undesirable symptoms.

Overdose of Mexidol

A significant excess of the doses recommended by the doctor leads to severe drowsiness. In this case, gently stop therapy with the drug and conduct symptomatic treatment.

Analogues of the drug

The most popular analogues of Mexidol in therapeutic effect and composition are: Mexiprim, Mexipridol, Astrox. “Mexicor”, “Armadin”, “Medomeksi”.

It is worth considering that all of these drugs have certain contraindications, can be the cause of the development of negative symptoms. Replacement of the drug should be carried out strictly after consultation with a specialist.

It is important to remember that therapy with this remedy should be carried out exclusively on the recommendation of a doctor.

We examined how to administer Mexidol injections intramuscularly.