Every year, bones in a person become more fragile. Joint fluid receives insufficient amounts of phosphorus and calcium. All this leads to the formation of arthrosis and osteoporosis. To stop the aging process in the joints, it is necessary to carry out preventive measures. An excellent tool for restoring the metabolism in bones is Oksidevit (solution). Instructions for use will familiarize the patient with the indications and contraindications in the treatment of this agent.
Pharmacological action of the drug
The solution "Oksidevit" helps to regulate the metabolism of calcium and phosphorus in the body. Also increases hydroxyvitamin D3. Increases the metabolism of these drugs in the intestines, kidneys. Restores bone mineralization. The main substance that is part of the solution is alfacalcidol. One milliliter of solution contains 2 mcg. Auxiliary components of the solution: citric acid, ethanol, tocopherol, sorbetol, purified water. The medicine is packaged in cardboard boxes. Ampoules contain from 0.5 to 1 ml of the product and are made of dark glass. The drug is administered intravenously, previously diluted with saline.
When the main substance enters the stomach, it is quickly excreted from it. The activity of the drug in blood plasma ranges from 8 to 18 hours. Alfacalcidol breaks down in the liver and forms a metabolite of calcitriol. A smaller part of this substance dissolves in bone tissue. Such important functions are performed by Oksidevit solution. Instructions for use, reviews, prices - all this is worth exploring before starting treatment.
Dosage and interaction with other medicines
The dosage of the drug is prescribed in a purely individual order. All envy on the course of the disease and the characteristics of the human body. The permissible dose per day for an adult is from 0.07 to 20 mcg. For children, from 0.01 to 0.08 mcg.
With the joint use of funds for the induction of microsomal liver enzymes, the effect of the Oxydevit solution decreases. Therefore, in such cases, it is recommended to increase the dosage.
If alfacalcidol is taken with digitalis solution, arrhythmia may occur. When prescribing calcium preparations and diuretics with Oksidevit solution, the risk of developing hypercalcemia increases. When taken together with laxative drugs, it is possible to get hypermagnemia.
All
anticonvulsants and antiepileptic drugs are very poorly combined with Oksidevit solution - its activity decreases many times. Mineral oils, colisteramine, albumin, antacids together with the solution will reduce its absorption. It is also not recommended to prescribe a drug with
vitamin D3 and its derivatives. All these warnings must be taken into account when treating with Oksidevit solution. Instructions for use will be able to talk more about the drug and its purpose.
Side effects
From the gastrointestinal tract, nausea, vomiting, dry mouth, epigastric pain, constipation may occur. Biochemical blood counts may vary slightly. The nervous system responds to the drug with drowsiness, dizziness, and headache. Also, in rare cases, tachycardia, weakness occurs. Perhaps the development of an allergic reaction in the form of a rash and itching. Side effects must be considered when taking the solution "Oksidevit". Instructions for use should be studied before starting treatment.
Indications and contraindications Oksidevit solution
Treatment with the drug is prescribed for dystrophy of the spinous processes, including after a chronic process in the kidneys. It is prescribed for rickets and osteomalacia of various origins, osteoparosis, renal acidosis. And also with other pathologies that are caused by a decrease in the body of calcium and phosphorus. Only a specialist can prescribe the solution "Oksidevit". Instructions for use describe contraindications.
A medicine is not prescribed for diseases such as hypercalcemia, hyperphosphatemia, hypermagnemia, vitamin D. Poisoning is also a contraindication. In some cases, hypersensitivity to the main substance of the drug and its additional components may develop. During pregnancy, administering the medicine is not recommended. Caution is necessary to use the drug in chronic processes in the kidneys and liver. Before the appointment, you need to familiarize yourself with the contraindications of the drug "Oxidevit". Instructions for use contain this information set forth in a fairly accessible form.
Special recommendations
Very carefully, it is necessary to prescribe the drug to patients suffering from urolithiasis. Also for those who can quickly develop hypercalcemia. During the treatment period, special monitoring of the indicators of calcium and phosphorus in the urine and blood is necessary. According to the results of the analyzes, the dosage of the solution must be adjusted to avoid the development of side effects. Children very strictly need to calculate the dose of the drug. The doctor must take into account age-related features.
In some chronic diseases, the drug "Oxidevit" is not prescribed. Instructions for use describe contraindications in detail.
How to replace?
Could not find a suitable medicine in the pharmacy? A specialist will be able to recommend a high-quality analog. The Etalfa remedy has an excellent effect. This is a solution that regulates the exchange of phosphorus and calcium. The active ingredient is alfacalcidol.
The medication is similar in composition to the drug "Oxidevit." Instructions for use, price, dosage also do not differ. Both solutions can be purchased in almost every pharmacy for 700-800 rubles.
Reviews
Patients respond well to the presented solutions. A positive therapeutic effect is observed from the very first days. Patients have joint pain when walking. In blood and urine, the rate of calcium is normalized. The process of bone destruction during osteoporosis of various etiologies is suspended. Many experts advise and prescribe the solution "Oksidevit" for treatment. Instructions for use, reviews, the necessary dosage - all this information is recommended to be studied in advance.