"Isoprinosine" for children is an immunostimulating agent, available in the form of elongated white tablets. They have a biconvex shape, a strip on one side and a slight amine smell.
Isoprinosine for children not only stimulates the immune system, but also has an antiviral effect. The use of this drug helps to restore the function of lymphocytes in conditions when the body is in immunodepression, blastogenesis in monocytic cells also increases, the expression of membrane receptors on the surface of T-helpers is stimulated, the weakening of the activity of lymphocytic cells is not allowed, the inclusion of thymidine in them is normalized. The use of isoprinosine also stimulates the activity of cytotoxic T-lymphocytes and natural killers.
Isoprinosine for children shows in vivo antiviral activity against Herpes simplex viruses, measles virus and cytomegalovirus, type III T-cell lymphoma virus, influenza A and B, polioviruses, ECHO virus, equine encephalitis and encephalomyocarditis. The antiviral effect of the drug is provided by the inhibition of viral RNA and the enzyme dihydropteroate synthetase, which is involved in the replication of certain viruses. Thus, there is an increase in the suppression of RNA synthesis of lymphocytes by viruses, and this in turn inhibits the translation of viral proteins and the biosynthesis of viral RNA, and the production of lymphocytes, which possess the antiviral properties of gamma and alpha interferons, is increased.
Isoprinosine - instructions
For children: after taking the drug, it quickly spreads from the gastrointestinal tract. Within 1-2 hours, the maximum of the active substance in the blood plasma is reached . Inosine is metabolized rapidly and uric acid is formed. It is excreted together with urine within 1-2 days and there is no accumulation in the body.
Isoprinosine is an antibiotic, therefore it is used in the following cases:
- the presence of infections that are caused by the Herpes simplex virus, it can be chicken pox, herpetic keratitis, labial and genital herpes, herpes zoster;
- during the treatment of influenza and SARS;
- treatment of infectious mononucleosis, which is caused by the Epstein-Barr virus;
- the presence of cytomegalovirus infection;
- Isoprinosine is also used for children in the treatment of severe measles;
- during the treatment of human papillomavirus infection of the larynx and vocal cords ;
- when a molluscum contagiosum appears.
Contraindications of the use of this drug:
- the presence of an increased sensitivity of the body to the components that are part of isoprinosine;
- chronic renal failure, urolithiasis, arrhythmia, gout;
- Do not use for children under the age of three 3 years, or whose weight is less than 15 kilograms.
These tablets are taken only after a meal, while they must be washed down with plenty of water or other liquid. It is recommended to take 50 mg of the drug per kilogram of body weight, dividing the entire norm into 3-4 doses.
If the patient has severe forms of infectious diseases, then the indicated dose of the drug can be increased individually, but not more than 100 mg per kilogram of weight and carried out in 4-6 doses.
In the presence of acute diseases in children, the course of treatment with this drug is 5-14 days. The treatment process is carried out until the clinical symptoms disappear, and after that another 2 days. A longer treatment is also possible, which should be carried out under the strict supervision of a doctor.
Side effects from isoprinosine can be epigastric pain, constipation, joint pain, diarrhea, elevated uric acid in plasma, exacerbation of gout, dizziness, headache, polyuria.