Unfortunately, no one is safe from injuries. Some injuries are so severe that it is impossible to do without the help of a specialist. The doctor will not only help to avoid the inflammatory process, but also save the patient from unbearable pain. In case of serious injuries and after surgical interventions, the drug “Arthrosilen” is often used. Injections are prescribed in the most difficult cases. In pharmacies, you can find a medicine in the form of a solution, suppositories and tablets.
The composition of the medication
The drug belongs to the category of non-steroidal anti-inflammatory drugs. The main active ingredient is ketoprofen lysine salt. Additionally, substances such as sodium hydroxide, citric acid, and also purified water are used. The drug is delivered to pharmacies in glass ampoules, packed in cardboard boxes.
It has a complex effect means "Arthrosilen". Injections help relieve fever, remove inflammation, and also produce an analgesic effect. The patient feels relief in the first days of therapy. Ketoprofen lysine salt is a instant compound. Due to this, the patient’s gastrointestinal tract is practically not irritated during the treatment process. The main active ingredient does not affect the articular cartilage. During treatment, the patient does not feel morning stiffness and swelling of the joints.
Pharmacokinetics
During oral administration, the capsules of the drug are rapidly absorbed from the gastrointestinal tract. The maximum bioavailability can be 80% and is reached after 4-5 hours. Bioavailability indicators directly depend on the dose that the patient takes. Experts do not recommend taking the medicine with food. This contributes to a significant decrease in the bioavailability of the main active ingredient.
With intravenous or intramuscular administration, the drug is also absorbed quite quickly. The maximum concentration in blood plasma can be reached after 40 minutes. The therapeutic effect is maintained throughout the day. More than 95% of the main active ingredient binds to plasma proteins. Ketoprofen lysine salt easily penetrates through the walls of blood vessels and is distributed in tissues and organs. Due to this, the analgesic effect is achieved quite quickly.
Indications
Previously to be studied by those who received an injury, the instructions for use attached to the drug "Arthrosilen". Injections may not be given to everyone. The drug belongs to the category of potent and can be used for fairly serious injuries or as a prophylactic drug after surgery.
Short-term treatment of pain is acceptable for diseases of the musculoskeletal system. At the same time, it is prescribed only as part of the complex therapy "Arthrosilen" (injections). Reviews show that the drug partially eliminates inflammation, as well as relieves pain. To eliminate the cause of the disease, it is necessary to use special medications of a narrow profile.
You should not use the drug "Arthrosilen" without consulting a doctor. Injections also have their contraindications. In addition, experts do not recommend a potent remedy for minor injuries.
Contraindications
Instructions for use should be studied before using the drug "Arthrosilen". Injections can be done not for everyone. So, a potent drug is not prescribed to minor patients. Women can not use the product during pregnancy and lactation. There are also a number of serious contraindications related to the patient’s state of health. If a person is diagnosed with peptic ulcer and duodenal ulcer, bleeding disorders, diverticulitis or chronic renal failure, it is better to choose another medication.
As practice shows, in most cases it is in a hospital that treatment with the “Arthrosilen” drug is carried out. Injections can be prescribed only after a full examination of a sick person and diagnosis. A qualified specialist should initially study the patient's medical history in order to exclude the possible development of side effects and other negative reactions, not forgetting the existing contraindications. With caution, a medication is prescribed for patients suffering from diabetes mellitus, liver failure, chronic heart failure.
special instructions
Before starting treatment, a specialist must check the picture of peripheral blood, as well as the functional state of the liver and kidneys. It should be borne in mind that taking Arthrosilen may mask the presence of an infectious disease. This is due to the fact that the drug removes the pain syndrome, the patient's well-being improves significantly. In this case, the drug does not have any effect on the development of infection.
As the reviews show, at the beginning of therapy it causes rather unpleasant sensations of “Arthrosilen”. The injections are painful, and therefore patients are quite difficult to tolerate the procedure, although there are exceptions. Cases of loss of consciousness during manipulations are known to medicine. Experts recommend putting the injections in a supine position. Intramuscular injections are more unpleasant . However, the pain goes away pretty quickly.
Dosage
At the initial stage, the medicine is prescribed intravenously or intramuscularly at 160 mg per day (1 ampoule). In the most difficult cases, the daily rate can be doubled. The maximum daily dose should not exceed two ampoules. Patients over 65 years of age are not prescribed more than 160 mg per day. The same rule applies to people with liver failure. How long should I take Arthrosilen? Injections put no more than three days. Further, experts recommend switching to the use of suppositories or tablets. Injections are done only in a hospital setting.
You can prolong the duration of the drug by infusion, when the drug is administered intravenously for half an hour. The drug can be prepared on the basis of a solution of sodium chloride, an aqueous solution of levulose, a solution of dextose.
Procedural sisters say that people tolerate the administration of Arthrosilen in different ways. The injections are painful. As already mentioned, sometimes patients even for a short moment lost consciousness during the procedure. According to some patients, the pain syndrome is not so pronounced, although, of course, the sensations are rather unpleasant. If you take the injections in a supine position, the procedure is transferred a little easier.
Overdose
The dosage should be strictly observed using Arthrosilen (injections). Reviews of experts show that improper use of the drug can lead to a deterioration in the well-being of the patient. Gastrointestinal symptoms are unpleasant. The patient may feel nausea, stomach pain, dizziness.
In case of an overdose, symptomatic therapy is performed. The doctor must monitor the respiratory and cardiovascular systems.
Side effects
It can provoke the development of side effects of "Arthrosilen" (injections). Analogs can also contribute to unpleasant symptoms. Therefore, they should be used to treat a specific pathology only after consulting a doctor. From the digestive system, side effects can occur in the form of abdominal pain, stomatitis, increased activity of liver enzymes, erosive lesions of the gastrointestinal tract.
From the side of the central nervous system, dizziness, tremor of the extremities, vertigo, and disturbances of night sleep were observed. In some cases, visual impairment occurs. It is worth remembering that the drug "Arthrosilen" (injections) and alcohol are incompatible. Alcohol primarily contributes to the development of negative reactions. The most complex are side effects from the cardiovascular system. Patients may experience chest pain, tachycardia, syncope. Often hypertension develops.
Drug interaction
Inducers of microsomal oxidation in the liver, such as phenytoin, ethanol, rifampicin, barbiturates, significantly increase the metabolism of ketoprofen. While taking the “Arthrosilen” preparation, the effectiveness of uricosuric drugs may be reduced. It is not recommended to combine the medication with antihypertensive drugs, as well as diuretics.
With other non-steroidal anti-inflammatory drugs, it is necessary to combine the “Arthrosilen” injections with caution. The instruction states that such an interaction can lead to the development of gastric ulcer, as well as gastrointestinal bleeding. There is a high probability of impaired renal function.
With caution, the drug is prescribed to people suffering from diabetes. With the simultaneous use of ketoprofen and insulin, the concentration of the latter in the blood may increase. Diabetics need to recalculate the dose before starting treatment.
Drug Reviews
You can hear good reviews about Arthrosilen (injections). Intramuscularly, the drug is administered only in a hospital setting. Here, specialists monitor the patient's condition. Therefore, side effects develop quite rarely. Patients only complain of discomfort during the injection. However, according to them, the pain passes quickly enough. Suppositories and capsules "Arthrosilen" have also proven themselves well. In this form, the drug can be used at home. You must first consult a doctor.
Doctors note that side effects develop most often if the correct dosage is not observed. Doctors emphasize that with extreme caution it is worth taking medicine for people with kidney failure and diabetes.
If it was not possible to find the right drug in the pharmacy, the specialist will always be able to find a high-quality analogue. The most popular remedies that can replace the Arthrosilen medication will be described below.
Ketonal
The medicine belongs to the group of non-steroidal anti-inflammatory drugs. The solution can be used for intravenous or intramuscular administration. Ketoprofen acts as the main component. Additionally, the composition of the drug includes substances such as ethanol, propylene glycol, benzyl alcohol, purified water. The medication has an analgesic as well as anti-inflammatory effect. Prescribe a drug to eliminate pain in diseases such as gout, radiculitis, osteoarthritis. Often, the medicine is used in oncology.
The drug has its contraindications, as well as the drug "Arthrosilen". Instructions for use (injections), reviews of specialists, dosage - all this information should be studied before starting treatment. It is unacceptable to use Ketonal solution for bronchial asthma, hemophilia, and renal failure. Do not prescribe medication for women in the first trimester of pregnancy, as well as for patients under 15 years of age.
"Artrum"
This drug, like the previous ones, is based on ketoprofen. Additionally, such means as propylene glycol, benzyl alcohol, sodium hydroxide, purified water are used. The medicine is delivered to pharmacies in glass ampoules, packed in cardboard boxes. The medicine can be prescribed for rheumatoid arthritis, osteoarthritis, radiculitis. The drug is used in neurology and oncology as an aid to eliminate pain. The solution is not prescribed for minors.
Flamax
This non-steroidal anti-inflammatory drug is available in the form of a solution and capsules. The main active ingredient is also ketoprofen. Additionally, substances such as sodium hydroxide, benzyl alcohol, propylene glycol, and purified water are used in the solution. Flamax is used to eliminate pain during migraines, inflammatory processes of the pelvic organs. The drug can be used in dentistry after surgery.
The Flamax solution can cause discomfort during administration, as well as Arthrosilen (injections). Whether these injections are painful or not, depends on the individual characteristics of the patient's body. However, any unpleasant symptoms disappear within a few minutes after administration of the drug.