Some people confuse psychotic disorders with concepts such as mental disorders, mental illness, or mental illness. Experts say that this term refers to a whole group of serious deviations that affect the human mind. They change the ability of an individual to make correct judgments, to think clearly, to communicate effectively, to react emotionally and to behave appropriately. With more severe symptoms, it is difficult for patients with such a disease to keep in touch with reality. However, even the most serious psychoses are treatable.
To restore disturbed processes in the brain, doctors recommend taking special medications. The most popular and effective of them is Tioril.
Instructions for use, description, composition, cost and form of this medicine will be presented a little below.
Composition, form, description and packaging
What are the components of the drug Tioril? Instructions for use inform us that thioridazine acts as the active ingredient of this tool. As additional components, dibasic calcium phosphate (anhydrous), polyvinylpyrrolidone K-30, starch, talc and magnesium stearate are used.
This medicine goes on sale in the form of dark brown tablets. They have a small diameter, round shape and a film sheath. You can buy this tool in blisters and boxes of thick paper, respectively.
Pharmacodynamic features
What are thioryl tablets? Instructions for use (the price of the drug is not very high) reports that it is an antipsychotic or the so-called antipsychotic. It is a phenothiazine derivative (piperidine).
This medication is able to have antipsychotic as well as sedative effect (moderate). At the same time, it contributes to the appearance of marked inhibition.
When taking the drug in small doses, it reduces the feeling of anxiety and tension, and also has an anxiolytic effect. It should also be noted that this agent has antidepressant activity (moderate).
The extrapyramidal and antiemetic effect of this drug is very weak.
Pharmacokinetic properties
Is Tioril absorbed? Instructions (only an experienced doctor should select analogues of this tool) indicates that after taking the tablets inside, their active substance is absorbed quite quickly from the digestive tract. In the blood, the maximum concentration of the drug is achieved within 1-4 hours.
The metabolism of the drug is carried out in the liver, and it is excreted through the kidneys and together with bile. The elimination half-life makes 6-40 hours.
Indications for antipsychotic
For what purpose can a doctor recommend a drug like Tioril (tablets)? Instructions for use, reviews of specialists indicate that the medication in question is used in the following conditions:
- psychotic disorders, which are accompanied by excessive agitation (psychomotor) and hyperactivity;
- schizophrenia;
- mild depressive disorders;
- impaired behavior associated with neurological abnormalities or psychotic disorders;
- neurosis, which is accompanied by agitation, anxiety, fear or stress.
Contraindications
When should you not prescribe Tioril tablets? Instructions for use informs that this drug is not recommended for use in the presence of the following conditions:
- severe depression of the central nervous system;
- severe depression;
- children's age up to two years;
- coma;
- liver failure;
- blood diseases (including a medical history);
- severe diseases of CVS;
- hypersensitivity to thioridazine, as well as other phenothiazine derivatives.
Pills "Thioril": instruction
Reviews, price, description of this drug are presented in this article. How should it be used correctly? The dosage of this drug is set individually, taking into account the genesis of the symptoms, as well as their severity.
For children over 12 years of age and adults, the medication is prescribed in an amount of 20-600 mg per day. In this case, the frequency of use should be 2-4 times a day.
The highest dose of the drug is 800 mg per day. High-dose therapy should be continued for no more than 4 weeks.
For babies 2-5 years old, the medication is prescribed in an amount of 1 mg per kg per day. Children over this age are usually given 75 mg per day with a frequency of up to 4 times a day.
Side effects
What undesirable effects can the use of Tioril tablets cause? Instructions for use (the description of this medication was presented above) reports that this medication contributes to the development of many adverse reactions. These include the following:
- retinopathy pigmentosa;
- drowsiness, malignant antipsychotic syndrome, confusion, convulsions, anxiety, tardive dyskinesias, akathisia, extrapyramidal disorders, headaches, visual impairment;
- leukopenia, pancytopenia, agranulocytosis, eosinophilia, thrombocytopenia, granulocytopenia, aplastic anemia;
- dry mouth, cholestatic hepatitis, constipation, paralytic ileus, nausea, hypertrophy of the papillae of the tongue, vomiting;
- violation of ejaculation, hyperprolactinemia, decreased libido, menstrual irregularities;
- postural hypotension, tachycardia, cardiac arrhythmias, ECG changes;
- nasal congestion;
- melanosis
- urinary retention, photophobia, weight gain;
- angioedema, skin rash, exfoliative dermatitis, pruritus.
Overdose symptoms
In case of an overdose, the patient may develop confusion, increased drowsiness, depression of the respiratory center, urinary retention, hyperreflexia, arterial hypotension, convulsions, disorientation, arrhythmia and areflexia. In severe cases, coma and collapse occur.
With such standing, the patient is washed with a stomach and prescribed regular intake of activated carbon. Symptomatic treatment is also performed. With arterial hypotension, plasma substitutes are administered.
Drug interaction
Can Tioril tablets be combined with other medicines? The instruction for use states that with a combination of this medication with drugs that have a depressing effect on the central nervous system, as well as ethanol-containing drugs and alcohol, a depressive state may intensify.
The concomitant use of Tioril with Levodopa reduces its antiparkinsonian effect, and with lithium preparations it enhances the neurotoxic effect.
The medication in question can lower the concentration of phenobarbital in the blood, as well as reduce the effect of oral antidiabetic agents and anticoagulants.
The anticholinergic effect of Tioril tablets may be enhanced when combined with anticholinergics.
Special recommendations
What you need to know before taking Tioril tablets? The instruction for use states that with special care this medication is prescribed to people with impaired heart rhythm, severe respiratory diseases, heart diseases, renal failure, angle-closure glaucoma, Parkinson's disease, myasthenia gravis, prostatic hypertrophy, pheochromocytoma and epilepsy.
During treatment, alcohol should not be allowed.
Emaciated patients, the elderly, as well as suffering from diseases of the liver or kidneys, the drug is first prescribed in a low dosage, and then gradually increase it.
Analogs and price
The cost of Tioril tablets is about 130-150 rubles. If necessary, it can be replaced with drugs such as Sonapax, Apo-Thioridazine, Tyson, Meller, Thioridazine, Meller-200, Thiodazine and Ridazine.
It should be recalled that the funds listed can only be used after consulting a doctor.
Reviews
Now you know what the Tioril antipsychotic is. Instructions for use, reviews, prices are described in this article.
The antipsychotic drug “Tioril” is a very effective and effective agent. This is the opinion held not only by consumers of this medicine, but also by experienced specialists. It perfectly treats psychotic disorders, significantly reducing their symptoms, and improving the patient's condition.
The only drawback of this drug is the presence of a large number of adverse reactions. That is why taking it at one’s own discretion is highly discouraged.