In the article, we will review the reviews and instructions for use with Halixol.
It is a drug in the group of expectorant, as well as mucolytic drugs. The features of the use of the medication will be discussed in this article. At the end, you can read the reviews about the drug Halixol.
Pharmacodynamics, pharmacology and pharmacokinetics
According to the instructions for use with Halixol, the active bromhexine metabolite is ambroxol, which is part of mucolytic substances in the benzylamine group.
Due to increased production and increased activity of hydrolytic type enzymes that break down the bonds between mucopolysaccharides, it dilutes sputum. The substance improves its rheological characteristics, reduces adhesive characteristics and viscosity due to the stimulation of serous cells of the glands of the bronchial mucosa. It normalizes the ratio of serous and mucous components of sputum.
It enhances mucociliary transport, contributing to an increase in motor activity of the ciliated epithelium. Does not cause too strong secretion production, reduces spastic bronchial hyperreactivity. Helps to be developed surfactant.
Is Halixol suitable for children? Instructions for use contain information about this.
From the medicine, the effect is observed half an hour after taking it.
Penetrating into the human body, the drug is almost completely absorbed from the digestive tract. Its bioavailability is approximately equal to 60%. The period of plasma clearance is two hours.
With plasma proteins, communication is 80%. Penetrates through the placental barrier. During pregnancy, it should be taken with caution, since the concentration of the main component in a dose in excess of four times the content in the body of a woman was determined in the fetus.
In addition, the main substance passes into breast milk, and this may affect breastfeeding. Actively involved in the metabolism of the "first pass" through the liver. The elimination half-life is approximately seven hours. Approximately 90% of the dosage is excreted in the urine.
Indications
As indicated by the instructions for the use of Halixol, it is prescribed to patients with the following diseases:
- acute pathologies of the respiratory system, the course of which is complicated by the formation of sputum (they include: bronchitis, pneumonia, asthma);
- in inflammatory processes of ENT organs (including otitis media and sinusitis), the drug is used to thin the mucus.
Features of the reception
When prescribing tablets to patients, they should be taken with caution, since the drug can cause side effects. Instructions for use with Halixol tablets should be studied in advance.
For children over twelve years of age, tablets are given based on the following scheme:
- from the first to the third days, one tablet is prescribed three times a day, they should be taken after an equal period of time;
- from the third to the fifth to the seventh day, you need to take one tablet twice a day.
If the disease proceeds in an acute form, then three tablets should be consumed per day. Reception must be carried out at an equal time interval. Young patients up to twelve years old need to drink the medicine in a dosage of half a tablet two to three times a day.
In accordance with the instructions for use with Halixol syrup, the following therapeutic regimen should be observed when prescribing it:
- from the first to the third day, drink ten milliliters three times;
- from the third to the fifth day, ten milliliters, dividing the dose several times;
- the duration of treatment after five days is determined individually, taking into account the patient's condition, as well as the severity of the pathology.
- in the acute form of the disease, it is necessary to drink syrup ten milliliters three times a day throughout the treatment;
- small patients under five years of age are prescribed medicine exclusively in the form of a syrup;
- from two and a half to five years is prescribed in a dosage of 2.5 milliliters no more than three times a day;
- from two years, 2.5 milliliter syrup is also prescribed, the number of doses is reduced to two times.
This is confirmed by the instructions for use with Halixol.
Release form and composition
The drug "Halixol" is made in the form of tablets for oral administration, as well as in the form of syrup. The syrup is made in glass bottles with a volume of one hundred milliliters, in a cardboard box with a measuring cup, making the dosage of the drug more convenient.
Instructions for use with Halixol syrup are in each pack.
The tablets are round, white, flat, on the one hand risk, have no smell. They are packaged in blisters of ten pieces in a cardboard box, instructions are attached to the medicine, where the characteristics are described in detail.
Each tablet contains thirty milligrams of ambroxol hydrochloride, as well as auxiliary components, including lactose monohydrate.
The syrup is clear, colorless, with a specific aroma. Ten milliliters contains the active substance (30 mg), as well as auxiliary components, including citric acid and flavor.
So the instruction to Halixol tells us. The price will be indicated below.
Combination of drugs
The attending physician must be informed of any medications that the patient is taking, taking recently or planning in the future.
- Halixol can not be combined with cough medicines (for example, Codeine), as they can create difficulties for the release of sputum, which is diluted with ambroxol. It is necessary to avoid the use of these funds at the same time, except in those cases in which a similar combination was prescribed by a specialist.
- The advantage of Halixol in the form of syrup is that it facilitates the penetration of a number of antibiotics (Cefuroxime, Doxycycline, Erythromycin, Amoxicillin) into the secret that is secreted by the bronchi.
This is indicated in the instructions for use with Halixol.
Side effects
Against the background of the use of the drug, a negative reaction may manifest itself, expressed in symptoms such as:
- general weakness and headache;
- rhinorrhea, nausea, dry mouth, diarrhea, vomiting, gastralgia, constipation;
- dysuria;
- anaphylactic reactions, urticaria, exanthema.
An overdose of the drug can lead to nausea, diarrhea and pain. In this case, it is necessary to rinse the stomach and drink plenty of water. If necessary, prescribe treatment based on the patient's symptoms.
Contraindications
The drug is contraindicated in the presence of the following conditions:
- an allergy to some of the components that make up its composition;
- acute renal failure;
- ulcerative inflammation of the digestive tract;
- cannot be assigned to children under five years of age;
- diabetes (syrup is contraindicated).
During pregnancy
During pregnancy, it is necessary to refrain from the use of a number of drugs, including Halixol. If necessary, you can use the medicine, but a woman should always be under medical supervision.
In the first trimester, it is forbidden to take both forms of Halixon. In other periods of pregnancy, it is allowed to use the medicine exclusively in the form of a syrup.
During breastfeeding, you should stop taking the drug. This is due to the ability of the drug to penetrate the children's body through milk. If the use is urgently necessary, then its use is allowed, but a woman should temporarily stop lactation.
Storage
The drug must be protected from children and animals.
The medication should be stored in a dry place where the temperature will not be higher than twenty-five degrees. Other than that, it should be dark and cool. Compliance with these requirements is a prerequisite. If everything is in order, then the medicine can be used for five years. If it is overdue, then it is not allowed to receive.
Analogs
This product has the following analogues: Ambrobene, Pektolvan Ts, Fluditek, Abrol, Bronchorus, Acetylcysteine, ACC, Ambrosan, Lazolvan, Mucolvan, Bromhexin, “Carbocysteine”, “Bronchobos”, “Erdomed”, “Bronchovern”, “Medox”, “AmbroGexal”, “Mukobron”, “Pulmozyme”.
Some recommendations
Before taking the medicine, you should carefully read some of the recommendations.
It should be borne in mind that the syrup contains a high alcohol content. If side effects occur during treatment, the drug should be stopped and a specialist should be consulted.
To purchase the drug, you do not need to show a prescription from a doctor in a pharmacy. The drug "Halixol" is able to reduce the concentration of attention when driving, so you need to be especially careful on the roads.
Self-administration of the drug is not recommended, since with the wrong dosage or duration of treatment, negative effects can be observed in the human body.
If the patient worsens, it is necessary to refuse to take the drug. Then you should consult with a specialist regarding the continuation of treatment or the selection of a replacement medication.
This describes the instructions for use for Halixol.
Price
The cost of the drug is 120-150 rubles per package. It depends on the region and the pharmacy network. You can also buy medicine online on the Internet.
Reviews of Halixol
As a rule, reviews about this drug are mostly positive, which is another confirmation of the effectiveness of the drug. Patients like the convenience of the release form and low cost. In addition, pregnant women are allowed to take this medicine, and this is also an undoubted advantage.
Among the negative aspects, patients note an extensive list of side effects, contraindications and a small number of analogues with which Halixol can be replaced. In addition, some patients consider drowsiness and pain in the back to be a side effect. However, the overall impression of the drug is positive, its effectiveness is time-tested.
We reviewed the Halixol medication for instructions on use, price and reviews.