Enterofuril is given to children in the form of tablets and suspensions. The second option is preferable for young patients - the product has a pleasant aroma of banana, so the kids are less capricious. Capsules are presented in two dosage forms of the active compound. The substance on which Enterofuril is based is called nifuroxazide.
Technical details
Enterofuril on sale is presented in cardboard packages containing the manufacturer's accompanying documentation and the actual medicine - a bottle with a suspension or aluminum blisters in which ten tablets are sealed in individual cells. The instructions strictly indicate at what age Enterofuril children can be taken in what format. A description of the drug is also given. It is necessary to verify the information in the documentation and actually present in the package to make sure that the product is not fake.
"Enterofuril" in the form of tablets is a solid yellow specimen. Inside they are filled with yellow powder. There are two dosage options: the active compound in one tablet can be contained in an amount of 100 ml or twice as much. One package contains three blisters with capsules of a lower dosage or one or two more. The exact number of tablets must be specified on the outside of the carton.
Enterofuril suspension is yellow, thick enough and smells like banana. In any form, the drug is used orally. Vials with suspension contain 90 ml of the substance, made of tinted glass. The package contains a measuring spoon.
What is made of?
The composition of Enterofuril in the form of a suspension:
- nifuroxazide;
- sucrose;
- sodium hydroxide;
- flavoring;
- water;
- ethanol.
The manufacturer used carbomer, methyl parahydroxybenzoate and citric acid.
The composition of Enterofuril in the form of tablets:
- nifuroxazide;
- starch;
- sucrose;
- cellulose;
- magnesium stearate.
Terms of use
Enterofuril suspension and tablets are based on the antimicrobial compound - nifuroxazide. The tool is widely used in pathologies of the intestinal tract, provoked by infections.
"Enterofuril" - indications for use:
- diarrhea (acute, chronic) provoked by bacteria;
- chronic inflammatory diarrhea;
- violation of the stool caused by improper use of antibiotics;
- loose stools of unspecified nature.
Suspension, Enterofuril tablets are not used if infection with worms is detected.
Before using the drug, it is necessary to check the susceptibility of pathological microorganisms to the active compound.
Nifuroxazide acts locally, is not able to penetrate the tissues and organs of the body, accumulate in the cells. The antibiotic is used strictly for disorders of the stool, it stops the production of enterotoxins, which means it reduces the irritability of enterocytes, against which the amount of salts and fluids produced by the intestines slightly decreases.
Doses and effects
As indicated in the instructions, for children "Enterofuril" in a low, medium dosage is recommended as a bacteriostatic drug. The active substance inhibits the activity of enzymes, which disrupts the production of substances vital for pathological microorganisms. With increasing doses, Enterofuril has a bactericidal effect, disrupts the membrane structure of the cytoplasm and provokes the mass death of bacteria.
When using Enterofuril according to the instructions (for children, the doses recommended by the manufacturer must be observed), there is no negative effect on the natural microflora of the intestinal tract. At the same time, some adverse reactions are still possible.
Indications "Enterofuril" include infection:
- staphilo, streptococci;
- salmonella;
- Escherichia coli;
- Klebsiella;
- enterobacteria;
- shigella.
Studies have shown that Enterofuril does not provoke the development of superinfection, does not lead to the formation of immunity in pathological microorganisms, does not increase the resistance of dangerous life forms to other antimicrobial agents.
As indicated in the instructions, Enterofuril is safe for children and adults, since almost the entire amount of the drug (more than 99%) enters the intestinal tract. Active substances cannot be absorbed into the circulatory system. Conclusion is carried out with the contents of the intestine.
Contraindications
As indicated in the instructions, Enterofuril can not be used for:
- hypersensitivity to the active substance;
- intolerance to the nitrofuran series;
- allergic reaction to any additional components used in the production.
According to the instructions, Enterofuril for children in the form of a suspension is applicable if the patient is older than a month old. Tablets can be taken from three years.
An excess of "Enterofuril" in the body can provoke abdominal pain.
Side effects
Enterofuril rarely causes a negative response in children, but there are certain risks. The manufacturer indicates the possibility of:
- nausea
- vomiting
- stool disorders;
- an allergic reaction;
- pain in the abdomen.
An allergy can manifest itself with a skin rash, urticaria, and more severe responses:
- Quincke's edema;
- anaphylactic shock.
If adverse reactions occur, you should consult your doctor about the continuation of the course. Minor inconvenience caused by the composition does not require dosage adjustment or cancellation.
Doses and diagnoses
The dosage of Enterofuril for children should be chosen by the doctor based on the age, weight, general health of the patient, and the characteristics of the disease. The duration of the program is a week or more. Enterofuril can be used at any time, there is no dependence on meals. When choosing a suspension before each use, the container is thoroughly shaken until a homogeneous substance is obtained.
When treating patients up to six months of age, Enterofuril syrup is used for children. On the day, the drug is taken three times in 2.5 ml. Between doses, eight-hour intervals are maintained.
From the age of seven months to two years, Enterofuril is indicated in an amount of 2.5 ml. The drug is consumed four times a day.
From the age of three, you can use Enterofuril syrup for children, and capsules. The first option involves three times taking 5 ml of the composition. Tablets are used in 3-4 approaches. The maximum dose for 24 hours is 800 mg. At one time, use one or two capsules.
For adults, Enterofuril is recommended in an amount of 5 ml four times a day, if the format of the suspension is chosen, or four times a day in 100 or 200 mg capsules. The total dose when choosing tablets for 24 hours is 800 mg.
Since the instructions indicate how much to take "Enterofuril" to the child (seven days), the manufacturer's recommendations should be followed. If unpleasant symptoms persist at the end of the course, you will have to check with your doctor if treatment should continue.
Some features
There is no official information on an overdose of Enterofuril, since the active substance is not able to seep into the circulatory system and have a systemic effect on the body. If the drug is still associated with the symptoms of intoxication, it is necessary to organize a gastric lavage and symptomatic therapy.
Enterofuril pharmacy in capsules for children and in suspension is dispensed without presenting a doctor’s prescription. Tablets and syrup are suitable for use within three years from the date of manufacture. After opening the vial with the suspension, you must use the entire medication in 14 days. Dispose of residues.
To maintain quality, the medication should be at room temperature in a darkened room. Suspension should not be frozen.
Chemistry and biology
It is assumed that nifuroxazide shows a pronounced effect due to the presence in the substance of the NO2 group, capable of stopping dehydrogenase, destabilizing the reactions of the production of protein structures. The indications of Enterofuril are based on the activity of nifuroxazide relative to gram-positive pathological microscopic life forms, some gram-negative enterobacteria.
Nifuroxazide does not affect saprophytes. If acute diarrhea caused by bacterial invasion is established, Enterofuril in capsules for children and adults helps to stabilize eubiosis. With viral enterotropic infection, the use of nifuroxazide can prevent the appearance of superinfection.
As indicated in the instructions, Enterofuril for children with diarrhea is used only when the problem is caused by a bacterial infection. The drug is not suitable for the treatment of premature babies and infants younger than a month.
Special occasion
The manufacturer draws attention to the fact that Enterofuril can be used during the period of gestation, but only after consulting a doctor. The doctor assesses the obvious benefits of the drug and the possible risks to the fetus, warns the expectant mother about the possible negative consequences.
"Enterofuril" can not penetrate the circulatory system, so it is sometimes prescribed for breastfeeding. It also requires prior consultation with your doctor. As a rule, for the period of the course the child is transferred to artificial nutrition.
If "Enterofuril" is used for children with vomiting, stool disorders, it is necessary to combine a medication and an active drink. In especially severe cases, intravenous rehydration is indicated.
It is unacceptable to combine Enterofuril and alcohol.
In the treatment of infants, an analysis is first carried out for the presence of enzymes that transform sucrose. Only with the exclusion of insufficiency of such compounds can treatment be started.
Studies have shown that Enterofuril does not affect the ability to concentrate, respond, therefore, there are no restrictions on the management of mechanisms and transport.
Alternative: what to replace?
Among the popular analogues, it is worth mentioning medicines:
- "Smecta";
- Enterol;
- Intetrix
- "Furazolidone";
- Entoban
The analogue of Enterofuril for children, cheaper than the original version, is Furazolidone. The drug is not used for patients younger than one year of age, but from a year and older you can safely use it for intestinal disorders of various forms. However, before replacing the composition recommended by the doctor, it is necessary to clarify how reasonable this is: pathological microorganisms sensitive to Enterofuril may be immune to Furazolidone.
Another analogue of Enterofuril for children, cheaper than the drug discussed above, is Smecta.
“Intetrix” and “Entoban” have a pronounced effect in violation of stool of a bacterial nature, but these drugs are suitable only for adult patients.
Analogs: "Furazolidone"
The medication belongs to the nitrofuran series, has a pronounced antibacterial effect. The tool is recommended if diagnosed:
- diarrhea;
- enteritis;
- pyelitis;
- urethritis;
- vaginitis;
- dysentery;
- colpitis;
- giardiasis;
- paratyphoid;
- cystitis.
The tablets are suitable for patients eight years of age or older. The drug is used after a meal, drink plenty of water. Dosage depends on the diagnosis.
Paratyphoid, toxicoinfection, dysentery require the appointment of 0.1-0.15 g four times a day. The duration of the course is from five days to twice as much time. Cyclic use is allowed: six-day use, four-day break.
For children over eight years of age, "Furazolidone" is recommended in the amount of 6-7 mg per kilogram of body weight. The resulting total volume is divided into four approaches.
When giardiasis "Furazolidone" is used four times a day. The dose for adults is 0.1 g, for children - 6 mg per kilogram of weight. The duration of the program is from five days to twice as much time.
Urethritis requires the use of 0.1 g of Furazolidone four times a day. Duration - three days.
Colpitis should be treated with a combined approach: tablets supplement with candles. Orally up to four times a day, “Furazolidone” is used in an amount of 0.1 g. The duration of the program is three days. 5-6 g of the drug is injected into the vagina in powder form, mixed with milk sugar. Suppositories with furazolidone are used rectally. The total duration reaches two weeks.
Furazolidone should not be used for more than 10 days in a row.
For adults, the maximum daily volume is 0.8 g; single - 0.2 g.
Overdose and side effects
Excess "Furazolidone" in the body can manifest itself:
- anemia
- leukopenia;
- hepatitis.
"Furazolidone" in high doses is toxic to the nervous system. When symptoms of an overdose appear, the reception is immediately stopped, the stomach is washed, antihistamines and calcium chloride are used. To maintain the condition, the patient is given B vitamins.
Against the background of taking "Furazolidone" are possible:
- vomiting
- nausea;
- loss of appetite.
"Furazolidone" in an adequate amount is toxic to a low degree, but can provoke an allergic response to the body.
Contraindications and special cases
“Furazolidone” is strictly prohibited if:
- hypersensitivity to substances used in the manufacture of the medication;
- renal failure in the terminal stage.
"Furazolidone" is not used to treat children under one month of age.
Exceptional accuracy requires the use of an antimicrobial composition if diseases of the nervous system and liver are detected. Pregnant women deserve no less attention. "Furazolidone" is allowed in an "interesting" position, but only in a situation where the doctor can monitor the patient's condition. At the same time, the positive aspects of use, the possible dangers for the maternal and children's body are analyzed. If the benefit is more significant than the possible harm, "Furazolidone" is prescribed, warning the patient about all the possible consequences of such a course.
"Furazolidone" passes into breast milk. If necessary, take tablets during lactation, the child is transferred to artificial nutrition.
Under the influence of the active component, the ability to concentrate attention may deteriorate, therefore it is recommended to abandon transport control and work with high-precision mechanisms during treatment.
Compatibility
When taking Furazolidone, you must refrain from foods rich in tyramine:
- coffee;
- cheese;
- milk, cream.
Take into account that "Furazolidone" reduces the effectiveness of MAO, so the antibiotic is not combined with MAO inhibitors. The activation of the effect of the drug is observed against the background of tetracycline, aminoglycosides. With the simultaneous use of "Furazolidone" and ristomycin, chloramphenicol, the hematopoietic function of the body is inhibited. When taking drugs that change the acid-base environment of urine, the duration of the removal of furazolidone is adjusted.
Analogues of Enterofuril: Smecta
Smecta is quite different from the preparations described above: it is a natural substance based on aluminum, magnesium silicate. Under the influence of the active compound, the state of the intestinal mucosa is normalized, mucus production is stimulated, and the protective level of the gastrointestinal tract increases. Smecta absorbs pathological life forms and helps to remove them from the body without inhibiting the intestines. "Smecta" is used for diarrhea from a month old. The drug is suitable for both children and adults.
"Smecta" is used for chronic stool disorders, effective in acute form of diarrhea. As a rule, it is an element of complex treatment. With diarrhea you need to drink a lot. The manufacturer recommends using Smecta for pain in the stomach, intestines, and esophagus. The drug does not eliminate the cause of the pain, but it stops the discomfort.
Features of the reception
Children older than one month of age, but younger than a year old “Smecta” are suitable in the amount of two bags per day. The course of treatment is three days. After the main program, they continue to use Smecta in the amount of one sachet per day. Duration - at the discretion of the doctor.
At the age of one year and older, a three-day course involves the daily use of four sachets of the composition, supporting treatment requires half the amount.
For adult patients, Smecta is recommended in the amount of three doses per day, but at the beginning of the course, up to six servings can be used.
In the acute form of loose stools, medications are required to stabilize the electrolyte balance. You need to drink a lot. In some cases, intravenous infusion is indicated to prevent dehydration.
Application rules
Right before use, the contents of one sachet are poured into a container and filled with half a glass of pure water, stirred until a homogeneous substance is obtained and immediately taken. If esophagitis is established, you should use the composition after a meal, in other cases - between meals.
You can prepare Smecta for a child in a bottle: sachets are diluted with 50 ml of liquid, a drink is used throughout the day. You can mix the drug with broths, mashed potatoes, juices, and other products used in baby food.
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