Surely many people experienced the suffocating effect of coughing. This condition is called forced expiration through the oral cavity, which is caused by contractions of muscle tissue in the respiratory tract. This happens due to irritation of a huge number of receptors that are located along the entire respiratory tract.
What is the physiological role of cough? This process helps to cleanse the respiratory tract of various substances, as well as the prevention of mechanical obstructions that violate the patency of the airways.
As you know, coughing is an unconditioned reflex. It usually manifests itself in diseases of the respiratory tract. How to get rid of it faster? Experts recommend using a drug such as Rengalin. Instructions for use, reviews, analogues and the price of the product in question are presented by us further.
The composition of the drug and its release form
In what form is the medicine “Rengalin” made for cough? Reviews report that this tool is available in the form of cylindrical tablets for resorption of white color, with a bevel and a risk.
There is an engraving of MATERIA MEDICA on one side of this medicine, and RENGALIN on the other.
According to the instructions, one tablet contains:
- antibodies to bradykinin;
- antibodies to histamine;
- antibodies to morphine.
These components are applied to lactose as a mixture of 3 active alcohol-water dilutions of the substance.
It is impossible not to say that Rengalin for cough, the reviews of which are indicated below, includes such auxiliary components as isomalt, anhydrous citric acid, sodium saccharin, magnesium stearate and sodium cyclamate.
This product is sold in blister packs of aluminum foil or PVC, which are packed in a cardboard box.
Features of the drug
What is remarkable about the Rengalin medicine? Instructions, use, reviews about this drug are presented in this article.
Experts say that the medication in question has bronchodilator and antitussive properties. In addition, due to its complex composition, this agent is capable of exerting decongestant, anti-inflammatory, anti-allergic, analgesic and antispasmodic effects.
Due to the modification of bradykinin-dependent activation of B1 receptors and histamine-dependent activation of H1 receptors, this drug selectively inhibits the links (central) of the cough reflex, and also reduces the excitability of the cough center, which is located in the medulla oblongata.
By suppressing the centers of pain sensitivity in the thalamus, the aforementioned medicine is able to block the transmission of pain impulses to the cerebral cortex.
It is impossible not to say that the drug "Rengalin", reviews of which everyone can leave, inhibits the flow of pain impulses from the periphery. This is due to a decrease in the release of plasma and tissue algogens (including histamine, bradykinin, PG).
What other properties do Rengaline cough tablets have? Reviews claim that, unlike narcotic analgesics, this drug does not cause drug dependence and respiratory depression, and also does not have sleeping pills and narcotics.
The use of this drug helps to alleviate the manifestations of acute pharyngitis, bronchitis, laryngitis and reduce bronchospasm. In addition, this tool relieves local and systemic signs of allergic reactions. This is due to the effect on the release and synthesis of bradykinin and histamine from mast cells.
Kinetic indicators of the drug
What pharmacokinetic parameters are characteristic for the drug “Rengalin” for cough? Experts say that the sensitivity of modern physical and chemical methods of analysis (for example, chromatography-mass spectrometry, gas-liquid chromatography and high-performance liquid chromatography) does not allow to fully evaluate the content of ultra-low doses of antibodies in human organs, biological fluids and tissues. This makes it technically impossible to study the pharmacokinetics of the drug.
Medication indications
What is the prescribed drug prescribed from? As a rule, it is used for productive and unproductive coughs that arose with acute pharyngitis, flu, acute obstructive laryngitis, acute respiratory viral infections, chronic bronchitis, laryngotracheitis, as well as other allergic and infectious and inflammatory diseases of the upper and lower respiratory tract.
In addition, this drug can be prescribed for acute and chronic diseases of the respiratory tract, which are accompanied not only by coughing, but also by bronchospasm.
Drug contraindications
When should a patient not prescribe Rengalin for coughing? Reviews argue that such a remedy is contraindicated in the presence of increased individual sensitivity to its ingredients. Also, this medicine is forbidden to use in children under three years of age (due to insufficient data on its safety and effectiveness).
Method of using a drug such as Rengalin for coughing
For children (reviews of this medicine are described below), this medication is given only after reaching the age of three.
It should immediately be noted that drugs of this kind should be taken only inside.
A feature of the drug in question is that it does not need to be washed down with water or any other liquid. For the treatment of cough, the tablet should be kept in the oral cavity until it is completely dissolved. Only one tablet is needed at a time.
The dosage of this remedy depends on the age category of the patient and on the degree of his illness. At least three tablets should be absorbed per day.
To achieve a therapeutic result, you should always consult a doctor before taking this drug. As a rule, on the first day, the doctor recommends taking up to four to six tablets. But this is only if the person’s condition is very serious. With a milder course of the disease, the indicated amount of the drug can be reduced.
Side effects
The medicine “Rengalin” for coughing (reviews, the price of the drug is indicated at the end of the article) helps very well. However, in some cases, this medication can cause adverse reactions. Usually they arise due to the individual intolerance of any components of the drug that are part of it.
It should also be noted that side effects after taking the drug in question may occur due to exceeding the dose recommended by the doctor. In this case, a person has dyspeptic symptoms. To eliminate them, symptomatic therapy is necessary.
Interaction with other drugs
To date, there is no evidence that the drug in question is contraindicated for simultaneous use with other medicines. But, in any case, before starting treatment with this agent, the patient must consult a specialist who, taking into account the indications and the general condition of the patient, will determine the impossibility or possibility of therapy with this drug.
Special recommendations
The medication in question does not affect the patient's ability to drive a car. The same applies to activities with dangerous machinery.
The drug "Rengalin" for cough: reviews, price, analogues
How much is the medication in question? The price of this drug in the Russian Federation is about 205 rubles.
If required, this drug can be replaced with similar drugs. As a rule, they include the following: “Glycodin”, “Codelac-Fito”, “Conderfin”, “Codelac”, “Cofanol”, “Broncholithin”, “Terpincod”, “Alex-Plus”, “Bronchocin”, “Codelmix” ".
As for consumer reviews, they are mostly positive. Patients claim that this drug really helps eliminate the cough. Moreover, it has a therapeutic effect on the very cause of this ailment.
Also, the main advantages of the drug in question include its availability in all pharmacies, the relatively low cost and the ability to use for young children (from three years).