The drug "Seretide" (inhaler) is a combination agent. The composition of the medication includes: fluticasone propionate and salmeterol. Components have various mechanisms of action.
Salmeterol is able to prevent bronchospasm. Fluticasone propionate prevents the development of exacerbation, improves lung activity.
The drug "Seretide" may become an alternative drug for patients receiving both inhaled GCS and a beta 2-adrenergic agonist.
Salmeterol has pharmacological properties that provide protection against histamine-induced bronchoconstriction. The component contributes to the development of longer bronchodilation (at least twelve hours) than beta 2-adrenoreceptor agonists of non-prolonged (short) action. Within ten to twenty minutes after administration, the onset of the bronchodilator effect is noted.
Fluticasone propionate is a topical glucocorticosteroid. The introduction of recommended dosages has a pronounced anti-allergenic and anti-inflammatory property. The component helps to alleviate clinical manifestations, reduce the incidence of exacerbations, accompanied by obstruction in the airways.
Prolonged use of fluticasone inhalation propionate at the maximum recommended dosages is allowed only if the daily production of hormones in the adrenal cortex is within normal limits in both children and adults.
The drug "Seretide". Instruction Indications.
The drug is prescribed for basic therapy of pathologies accompanied by obstructive phenomena in the respiratory tract of a reversible nature (including bronchial asthma in adults and children) in cases of the appropriateness of using combined treatment, including a drug from a number of inhaled GCS (glucocorticosteroids) and bronchodilator in patients:
- receiving regularly receiving therapy with bronchodilators and in need of glucocorticosteroids (inhalation);
- in which symptoms of the disease persist against the treatment of corticosteroids;
- receiving effective dosages (supportive) of beta2-adrenergic receptor agonists of prolonged exposure and inhaled GCS.
The drug is recommended as a supportive treatment for COPD.
The medicine "Seretide". Instructions for use.
The drug is designed only for inhalation.
In order to obtain the optimal therapeutic effect, the Seretide drug is recommended to be used regularly, even in the absence of clinical signs of COPD and bronchial asthma.
Only the attending physician can determine the dosage and duration of treatment with Seretide. The instruction recommends prescribing such a dosage form of the drug in which the amount of fluconazole propionate corresponds to the severity of the pathology.
For patients of advanced age and with impaired liver or kidney activity, a dosage reduction to the minimum effective is not required.
Before using the inhaler for the first time or after a long break (from a week or longer), you should remove the cap from the mouthpiece by shaking the device and releasing the aerosol jet into the air.
- For inhalation, it is necessary to transfer the device to the upside down position.
- After making a deep exhalation, place the mouthpiece in your mouth, clasp your lips.
- Starting a breath, press the top of the inhaler until the aerosol exits, while continuing to inhale.
- Holding their breath, remove the mouthpiece from the mouth.
- The second dose is obtained after thirty seconds.
"Seretide" instruction does not recommend the appointment of patients under four years of age, with hypersensitivity.
The use of the drug during lactation and during gestation is carried out on the recommendation and under the supervision of a doctor.