The drug "Milgamma" (injections), the use of which is carried out strictly according to the doctor's prescription, includes a complex of vitamins of group B. The components contribute to the elimination of degenerative and inflammatory pathologies of the motor and nervous systems.
Structure
Vitamin B1 is considered a key component in carbohydrate metabolism. The compound is involved in the Krebs cycle and the synthesis of thiamine pyrophosphate and ATP. Pyridoxine (B6) is an element of protein metabolism. Partially the component is involved in the metabolism of fats and carbohydrates. The physiological function of these compounds is the mutual potentiation of activity. As a result, a positive effect on the cardiovascular and neuromuscular systems is noted. Due to deficiency of B6, the introduction of these components contributes to the rapid completion of the deficiency. Cyanocobalamin (B12) promotes the synthesis of the myelin sheath. The component stimulates hematopoiesis, reduces pain caused by lesions in the nervous (peripheral) system. The compound also normalizes nucleic acid metabolism by activation of folic acid. As a local anesthetic, lidocaine is present in the composition of the drug. This component provides various types of anesthesia (conduction, infiltration, terminal).
Pharmacokinetics
With the intravenous administration of the Milgamma preparation, the indications for the use of which will be described below, rapid absorption of thiamine is noted. The component actively penetrates the blood, reaching a maximum concentration 15 minutes after the injection. When introduced into the muscle, pyridoxine is rapidly absorbed and distributed in the body. The component plays the role of coenzyme. Pyridoxine passes the placental barrier, is found in milk.
The drug "Milgamma". Indications
The medicine is recommended as a symptomatic and pathogenetic agent in the complex treatment of syndromes and diseases of the nervous system of different origin. A medication is prescribed, in particular, for neuritis (including retrobulbar), neuralgia, paresis of the facial nerve. With ganglionitis (including herpes zoster), plexopathy, polyneuropathy (neuropathic, alcoholic), the drug Milgamma is also recommended. Indications for use of the drug also include lumbar ischialgia, radiculopathy, muscle-tonic syndromes. The medicine effectively helps to eliminate the manifestations of neurological type osteochondrosis, night cramps, especially in patients of an older age group.
Dosage regimen
When prescribing the administration scheme of the drug "Milgamma", indications for use are a fundamental factor. The tolerance and age of the patient are also taken into account. With severe pain, it is more advisable to start therapy with an introduction into the muscle. The dose is 2 ml. The drug is administered every day for 5-10 days. In the future, the patient (with an improvement in condition) is prescribed more rare injections or is transferred to the oral form of Milgamma. Indications for use of the drug include quite serious pathologies. In this regard, therapy is carried out under the supervision of a physician.