The drug is intended for parenteral use, it belongs to the clinical and pharmacological group of drugs that improve tissue repair processes, as well as the energy balance of cells. Why are Solcoseryl injections prescribed? According to reviews, it is known that the drug is used for pathogenetic therapy of various pathologies that are accompanied by a violation of trophic cells and tissues.
Structure
The medication is available in the form of a solution that has a yellow tint. It is colorless and has a characteristic aroma of meat broth. The main active ingredient of Solcoseryl is a preparation from the tissues and blood of cattle (healthy dairy calves), its concentration in one milliliter of the solution is 42.5 milligrams.
An additional substance of the solution is sterile water for injections. A solution for parenteral administration is dispensed from pharmacies in ampoules of dark glass with a volume of two and five milliliters. They are placed in cell packages of five pieces. There are 1 or 5 of them in the box.
What are the medicinal properties of the drug
According to the instructions for use and reviews of Solcoseryl injections, it is known that the main active component of the solution - deproteinized dialysate from the blood of healthy dairy calves - has several pharmacological effects:
- It improves the functional state of capillaries and the system of small vessels, including arterioles, hemocapillaries, venules, as well as arteriovenular anastomoses, which leads to an increase in the movement of blood in the tissues and their nutrition.
- Increases energy formation in cells by increasing the activity of the metabolic pathway.
- Increases the intensity of the production of fibrillar protein, which is considered the main structural component of the component of connective tissue.
- Promotes an increase in its quantity.
There is no exact information about the pharmacokinetic properties of the Solcoseryl solution today.
Indications
The solution is used to improve microcirculation and tissue trophism in several pathologies of the body, which include:
- The defeat of the peripheral arteries, which is characterized by a violation of the blood flow in them, especially this occurs at the third or fourth stage of the onset of pathology.
- Chronic venous insufficiency, which is accompanied by a decrease in the functioning of peripheral veins of different locations.
- Violation of cerebral microcirculation with damage to brain tissue, as well as a violation of its functions as a result of obstruction or cessation of blood flow.
- An acute violation of cerebral microcirculation with a breakthrough of capillaries and cerebral hemorrhage.
- Cerebral sclerosis (a disease that manifests itself as a disorder of various brain functions).
- Stomach ulcer.
In addition, Solcoseryl is used in the complex treatment of impaired functioning of the brain after an injury. And also the medication is used to eliminate gynecological diseases.
What limitations does the drug have
There are certain conditions in which the use of the solution is prohibited. These include:
- Pregnancy.
- Breast-feeding.
- Individual intolerance to the active substance.
- Hypersensitivity to benzoic acid or its chemical derivatives.
- The age of the patient is up to eighteen years.
With extreme caution, the medication is used in the following conditions:
- Liver disease.
- Hyperkalemia (an ailment characterized by an increase in the concentration of potassium in the bloodstream).
- Arrhythmias (a pathological condition leading to a violation of the frequency, rhythm and sequence of excitation and contraction of the heart).
Before treatment, you need to make sure that there are no restrictions on the use of the drug.
Mode of application
"Solcoseryl" is intended for intravenous infusion, for this the drug is dissolved in 250 milliliters of a five percent glucose solution, and then injected into a vein. The dosage and dosage regimen of the medicine depends on the indications for its use:
- With a head injury, use 10 milliliters intravenously drip for ten days. Then 2 ml once a day for one month.
- In chronic venous insufficiency, the solution is administered intravenously at 10 milliliters three times a week, the duration of therapy should not exceed four weeks. In case of trophic skin defects in the area of ββthe affected vein, ointment or Solcoseryl gel can be additionally used.
- In case of damage to the peripheral arteries on a daily basis, 20 milliliters of the drug is administered intravenously drip for four weeks.
According to reviews, intramuscular injections of Solcoseryl are given when intravenous administration is not possible (2 ml twice a day). Multiplicity, duration of use of the medicine is prescribed by the doctor.
With burn injuries, an intravenous administration of the drug is prescribed, the dosage is from 10 to 20 milliliters of solution per day. In severe skin disorders, an infusion infusion is possible - 50 milliliters of the drug. The duration of pharmacological dosing is determined by the doctor.
According to reviews in gynecology, Solcoseryl injections are best replaced by intravenous injection. The prescribed drug must be dissolved in 250 milliliters of saline and injected with a slow stream for about sixty minutes.
With intravenous injections, a preliminary dilution of the drug is necessary - 20 ml is diluted in 200 milliliters in sodium chloride. Solcoseryl must be administered slowly. Intramuscularly injected no more than 5 milliliters of pure solution.
According to reviews, Solcoseryl injections for stomach ulcers are used once a day for 20 milligrams intramuscularly. For prevention, it is recommended to reduce the dosage of the active active substance to 5 mg per day.
With difficult wounds, doctors advise the use of 6 to 10 milliliters of the solution intravenously.
Negative effects
According to reviews, injections "Solcoseryl" side effects also cause, like any other drug. But in most cases, the medication is well tolerated by patients. Sometimes when using it, allergies can occur in the form of rashes on the skin, itching, characteristic changes that are somewhat reminiscent of a nettle burn, an increase in body temperature.
In addition, local reactions may occur in the injection area in the form of redness of the epidermis. If negative effects occur, the possibility of further use of the drug is determined by a medical specialist.
special instructions
Before using the solution, we recommend that you carefully read the instructions. There are several features that include:
- If pathological reactions occur when using the medication, complex treatment is prescribed.
- To use the drug for women in position and during breastfeeding is not recommended.
- The Solcoseryl infusion solution cannot be used with certain medicines of other therapeutic groups, for example, ginkgo biloba, as well as bicyclan fumarate and naftidrofuril.
- The active substance of the drug does not directly affect the functional state of the central nervous system.
In pharmacies, the solution for parenteral administration "Solcoseryl" is dispensed strictly according to the prescription of a medical specialist. Its self-administration without an appropriate purpose is excluded.
To date, cases of poisoning with a solution for parenteral administration have not been recorded.
Analogues of Solcoseryl. Storage
Medicines are considered similar in composition and pharmacological effect:
- Chimes.
- "Actovegin".
The shelf life of the drug "Solcoseryl" is sixty months. The medicine should be kept in its original packaging, as well as in a dark, dry place, away from children, at room temperature.
Opinions
Almost all the reviews on Solkoseril injections left on the Internet are positive. Negative responses are rare, they are caused to a greater extent by the fact that the medication caused an allergy, which is associated with intolerance to the active substance.
Rapid action of the drug, as well as good tolerance of Solcoseryl, the absence of negative reactions are noted. The negative effects include pain during the administration of the drug. This effect appears due to the presence of potassium in the medication.
The drug "Actovegin" has the same active component and a similar pharmacological effect. It can be used if the introduction of "Solcoseryl" provokes an allergic reaction.
Although the medication has few prohibitions and adverse reactions, uncontrolled use of the medication is unacceptable. The lack of information about the processes of interaction of the drug with the human body allows us to assume the likelihood of harming the patient. The need for the use of Solcoseryl and its dosage must be determined by a medical specialist.
Reviews about the drug allow us to conclude that this medication effectively copes with its task.