In the article, we consider the instructions for use for "Palin" from cystitis and reviews.
The onset of symptoms of cystitis immediately puts patients before the choice of drugs that they should use in the treatment of this pathology. As a rule, in most situations, the choice falls on certain antibacterial agents. And this is not accidental, because it is with the help of antibiotics that you can stop the disease. The Palin remedy for cystitis, according to reviews, is one of the most effective drugs that can quickly get rid of inflammatory processes in the bladder.
Efficiency
"Palin" - a drug from the category of antibiotics related to the quinolone series. The main active ingredient of this medication is pipemidic acid. The drug is endowed, depending on concentration, with bacteriostatic (it inhibits the growth of bacteria) or bactericidal properties (harmful to pathogens). Lower dosages of Palin act bacteriostatically, and high volumes provide bactericidal efficacy. This drug can also act effectively on gram-negative bacteria like Proteus, Escherichia coli, enterobacteria, cytrobacteria, etc. It is considered moderately active in relation to Providence, Klebsiella and Acinetobacter.
What else does the instruction for use with PALIN tablets for cystitis tell us?
The tool, as a rule, does not exert any effect on chlamydia, Pseudomonas aeruginosa, mycobacteria, anaerobic microscopic organisms (those that develop without oxygen) and on gram-positive flora. It is worth noting that the resistance of organisms to the drug usually develops slowly. This medicine is very well absorbed in the digestive system, reaching maximum concentrations in the bloodstream in just one to two hours. A high content of the drug is observed in the kidneys, as well as in the prostate gland.
This medication binds to blood plasma proteins by no more than thirty percent. It is excreted from the human body with urine, and in addition, through the intestines with bile. In twenty-four hours, fifty to eighty-five percent of the dosage received is excreted. This agent can pass through the placenta and in small quantities into breast milk. The medicine for cystitis "Palin" is used mainly for the treatment of urological and sometimes gynecological diseases.
Release form: capsules, suppositories and tablets
The tool is released immediately in several formats:
- There is a convenient form in tablets (400 milligrams of active ingredient is contained in one pill). They are packed in twenty pieces in one blister.
- In addition to tablets, this medicine can be purchased in capsule form. One capsule includes 200 milligrams of the main ingredient. They are also packaged in ten pieces per cell.
- Another form is suppositories. For example, one vaginal suppository contains 200 milligrams of the main component. This kind of medicine is applicable for the treatment of pathologies in women. In one package with the medicine are ten candles.
The instruction to "Palin" from cystitis
The medication is used to treat acute and chronic pathologies of the urinary canals and pelvic organs including. This tool is suitable for patients for the treatment of diseases that are caused by bacteria that are sensitive to the described drug, we are talking about the following ailments:
- The presence of urethritis or cystitis in patients.
- The development of prostatitis in men.
- Against the background of pyelonephritis.
Indications for women
The presented preparation can also be used as part of the complex treatment of vaginal infection in women. For example, this medication is often also used to prevent the recurrence of chronic pathologies of the urinary canal and various complications against the background of instrumental examination and manipulations in gynecological practice.
Is Palin cystitis treatment suitable for everyone?
Contraindications
It is worth mentioning some contraindications for taking this medication:
- The presence of individual intolerance in a patient of any ingredient of this therapeutic agent.
- The occurrence of epilepsy along with diseases of the central nervous system with the presence of convulsive syndrome.
- The development of renal failure due to creatinine clearance of less than 10 milliliters per minute.
- The occurrence of liver failure on the background of chronic active hepatitis, cirrhosis and the like.
- The development of porphyria, which is a hereditary disease with a violation of the synthesis of hemoglobin.
- The occurrence of pregnancy or lactation.
- The patient's age is up to fourteen years and the period when a person is older than seventy.
- The appearance of hypersensitivity to aspirin, and in addition to acetylsalicylic acid.
- The occurrence of hypersensitivity to other drugs related to the quinolone series.
With great care, the medication in question should be prescribed for patients who have previously suffered a violation in cerebral circulation. In this case, we are talking about hemorrhagic or ischemic stroke.
Side effects
According to reviews of "Palina" from cystitis, in the process of using this drug, patients can not do without some side effects. Moreover, in each case, their pathological reactions may occur. So, from the side of the digestive organs, the following is possible:
- The appearance of abdominal pain along with diarrhea, nausea, vomiting, heartburn and loss of appetite or its complete absence.
- The occurrence of increased gas formation in the intestine.
- It is worth noting that in rare examples, pseudomembranous colitis, which is an inflammation of the intestine caused by anaerobic microorganisms, is not excluded.
From the side of the functioning of the nervous system, the following side effects may appear:
- In extremely rare cases, convulsive seizures occur.
- It is equally rare to expect the appearance of a headache in combination with visual impairment, depression, agitation, hallucinations, confusion, trembling in the body, sleep failure, and the like.
On the part of the functioning of the blood and blood organs, the following is usually observed:
- Very rarely, a decrease in the number of eosinophils, acting as a variety of white blood cells, is noted.
- In elderly patients and in case of impaired renal function, a decrease in the number of platelets, that is, blood plates that are involved in its coagulation, can be recorded.
- In patients with congenital deficiency of the phosphate dehydrogenase enzyme, hemolytic anemia can occur, that is, anemia due to the destruction of red blood cells.
Among other things, allergic manifestations include urticaria along with pruritus, anaphylactic shock (severe reaction of an immediate nature with rapid loss of consciousness). In addition, Johnson's syndrome, which is a very severe reaction with damage to the skin and mucous membranes, is not excluded.
Other effects that cannot be ruled out include increased sensitivity of the patient to solar radiation, that is, photosensitivity along with the development of resistance of pathogens to the described drug. It is also possible the appearance of superinfection, when a layering of the pathology with other pathogens is observed.
Treatment with this tool
How to take "Palin" with cystitis? This means in tablets must be swallowed, it is forbidden to chew. The medicine is washed down with water (at least one glass). During therapy, the patient should consume at least two liters of fluid per day, controlling the amount of urine. During the “Palin” treatment period, it is recommended to avoid exposure to direct sunlight and ultraviolet radiation. With prolonged therapy with the drug, it is necessary to monitor the general blood test along with the functions of the liver and kidneys.
Drug dosage
Typically, the drug "Palin" is prescribed 200 milligrams twice a day with an interval of twelve hours. In some situations, for example, against the background of staphylococcal infections, the drug is prescribed in larger quantities, namely, 200 milligrams three times in eight hours. The duration of the treatment course is determined by the doctor individually. The average course of therapy is ten days, if necessary, the therapy is extended to six to eight weeks. Patients suffering from severe impaired renal function, carry out a dosage adjustment of this drug. Women can be prescribed simultaneously with pills, one vaginal suppository once a day at night for seven to ten days.
Interaction with various medicines
In the framework of the reception "Palina" from cystitis for women, the following interaction should be considered:
- Antacids (which are drugs that lower the acidity of the juice in the stomach) and sucralfate can reduce the absorption of the drug in the digestive system. In cases of the need for their combined use, it is necessary to observe the intervals between the use of drugs in two to three hours.
- With prolonged use in conjunction with caffeine and "Theophylline" this medication can contribute to an increase in the concentration of these drugs in the blood.
- The Palin remedy can lead to an increase in the effects of treatment with Rifampicin, Warfarin, non-specific anti-inflammatory drugs and Cimetidine.
- As part of the joint appointment of "Palina" with antibiotics from the aminoglycoside category, an increase in the bactericidal effect on microorganisms is noted.
- Against the background of the simultaneous administration of "Palina" with other drugs from the quinolone category and with non-narcotic painkillers, the risk of seizures increases.
"Palin" for children
The tool can cause an increase in muscle tone in children. Pipemidic acid, which is the main active ingredient of this medicine, accumulates in cartilage. For these reasons, “Palin” is never used for the treatment of children under the age of fourteen. As part of the treatment of children who are over fourteen years old, the medication is used for absolutely the same indications and in the same dosage as for adults.
During pregnancy
There are no studies to confirm the safety of using Palina during pregnancy. In this regard, this medication is not prescribed for pregnant women. Given that it passes into breast milk, during therapy, they should stop breast-feeding.
Reviews of "Palina" from cystitis in women will be examined in more detail.
The effectiveness of the drug for cystitis
According to urologists, over the years of using Palina, the sensitivity of microscopic organisms to the drug has changed in the framework of urological practice, that is, they have developed resistance to it. Therefore, this medicine can be recommended for the treatment of uncomplicated forms of acute or chronic cystitis. The use of “Palina” is advisable as a reserve preparation, when for some reason the use of modern antibiotics is impossible, for example, when Monural, Tsifran, Xenavin and other medicines cannot be treated. In any situation, self-medication of cystitis is dangerous and harmful. Only a doctor will be able to choose the right medication for treatment, dosage and duration of the therapeutic course.
In the presence of pyelonephritis
Currently, this medication can be used to treat an uncomplicated form of pyelonephritis. It is advisable to carry out antibacterial treatment, taking into account the sensitivity of bacterial pathogens isolated during bacteriological urinary culture. It is permissible to begin treatment with “Palina” in usual dosages in the first three days of the pathology.
After three days of use, the results of therapy are evaluated, paying attention to improving overall well-being, and in addition, urinalysis. After three days, a bacteriological urine test will be ready. In the event that the pathogen is sensitive to this medication and there are positive changes in well-being, therapy is continued for up to three to six weeks. Repeated bacteriological urine cultures are carried out periodically along with a test of the sensitivity of the pathogen.
In the instructions for use for "Palin" from cystitis, analogues are not indicated.
Analogues of the drug
Synonyms of the medication under consideration today are the medicines Pipegal, Pimidel, Urotractin, pipemidic acid, Uropimide and so on. Ciprofloxacin, along with Ciprolet, Ofloxacin, and Cifran, are analogues in the mechanism of action.
Reviews about "Palina" from cystitis
It is worth saying that among the reviews about this medication there are many positive, as well as negative opinions. Some people note a pronounced therapeutic effect of this remedy at a relatively low cost. Such comments approximately account for forty-one percent of the total. But there are also many reviews of women about “Palin” from cystitis, which indicate the lack of effect from its use.
The authors of these reports write that the low cost of the drug is consistent with its low quality. It is also important to note that many patients on the network urge others to be treated with more modern medications. Many authors of reviews of "Palina" from cystitis admit that they are repelled by an excessive number of adverse reactions, in this regard, people are forced to abandon its use and they have to look for analogues.
Medication cost
So, as noted earlier, the cost of this remedy is not at all so large, therefore it is absolutely affordable for citizens. For example, for the format of the tablets you need to pay from eighty to one hundred rubles. As for the capsules, they will cost the consumer from one hundred and ninety to two hundred and thirty rubles per package.
In conclusion, it is worth saying that usually antibiotic therapy is carried out for ten days, but in more severe cases, Palin cystitis tablets are prescribed for up to eight weeks. In the event that the doctor recommended using this medication for a longer time, then patients should be tested periodically, since there have been cases when there have been examples of the effect of this drug on blood counts.
We reviewed the instructions for use for "Palin" from cystitis and reviews of this drug.