The international name, which are tablets "Creon 10000" - "Pancreatin" (Pancreatin). The same name is used in the INN registry. It belongs to the group of digestive enzyme preparations.
The medicine can be produced by various manufacturers in the form of dragees, tablets, coated with a stomach-soluble coating, or capsules.
The pharmacological effect of the drug "Creon 10000" instructions for use are described as follows. Creon is a digestive enzyme that stabilizes pancreatic enzyme counts. This stabilization is achieved by the proteolytic and lipolytic effects of the drug. The composition of the drug includes lipase, trypsin, which are active pancreatic enzymes. They provide the breakdown of proteins, fats and starch into elements that significantly improve the functioning of the digestive tract. In addition, these elements contribute to the normalization of digestion processes. In particular, a component such as trypsin, significantly inhibits the secretion of pancreas and has an analgesic effect.
During the action of the drug in the alkaline environment of the intestine, enzymes are released, the maximum activity of which is achieved after ½ hour after administration.
The drug "Creon 10000" instruction recommends taking as a component of replacement therapy. The main indications for prescribing by a doctor are various forms of manifestation of exocrine pancreatic insufficiency - chronic pancreatitis, dyspepsia, flatulence, pancreatectomy and others. In addition, the drug is effective for general digestive disorders and in cases where it is necessary to compensate for nutrition errors. Before taking the drug, it is recommended that a study of the abdominal organs.
The drug "Creon 10000" can cause side effects. First of all, these are various allergic reactions and discomfort in the epigastric region, diarrhea or constipation, nausea can occur much less often. In the case of prolonged use of the drug or in excess of doses, hyperuricosuria may occur. In children, constipation can often occur, therefore, the appointment of a drug should be accompanied by special dosage control.
For the drug "Creon 10000", the instruction provides the following contraindications: it is strictly forbidden to take the drug for acute pancreatitis or for exacerbation of its chronic form. You should not take the medicine in the presence of hypersensitivity to its components.
Pancreatin in the "Creon 10000" dosage form should not be taken with food. This is done either directly during, or immediately after a meal. This ensures the most rapid absorption of the components of the drug. Drink a tablet with plenty of water or fruit juice.
The dosage of the drug is calculated on the amount of lipase contained in it, as well as in accordance with the age of the patient and the degree of pancreatic insufficiency. The standard daily dose for an adult is 150 thousand units, and the maximum (with complete failure) can reach 400 thousand units. For children, the maximum dose per day is 100 thousand units.
It is very important to keep in mind that the duration of treatment that can be carried out with the help of the "Creon 10000" preparation determines from several days to many years if the medicine is used as a replacement therapy. In such cases, it is recommended that the drug be taken with preparations containing iron elements.
With prolonged admission, you should constantly monitor the condition of the digestive tract and be under the supervision of a doctor.