How should I take the drug "Fexofast"? Instructions for using this medication will be described below. Also, information on which substances are part of the mentioned drug, for what purpose it is prescribed, whether it has contraindications and analogues, will be presented to your attention.
Composition, form and packaging of the medicine
Fexofast tablets, the instructions for which are in a cardboard box, contain such an active ingredient as fexofenadine. As for the additional components, microcrystalline cellulose, hypromellose, starch, magnesium stearate, povidone, colloidal silicon dioxide, lactose and purified water are used as them.
According to the instructions, the product in question is covered with a film coating. It contains components such as propylene glycol, talc, hydroxypropyl methyl cellulose, titanium dioxide, isopropyl alcohol, methylene chloride and a dye.
You can buy tablets of 180 and 120 mg in blisters and cardboard boxes, respectively.
Pharmacological characteristics of the drug
What features are inherent in Fexofast tablets? Instructions for use indicate that the drug in question is a blocker of H1-histamine receptors. Its active substance is a pharmacologically active metabolite of terfenadine.
The medication does not have a sedative effect, and also is not addictive (after a month of admission). The antihistamine effect of this agent appears after 60 minutes. It reaches its maximum after about 6 hours and lasts throughout the day.
Experts have found that when taking Fexofast orally in an amount of 10-130 mg, the therapeutic effectiveness of the active substance is dose-dependent.
Kinetic features
How long is Fexofast absorbed? Instructions for use say that after oral administration of tablets, their active substance is absorbed quite quickly from the intestines.
The highest concentration of the active ingredient in the blood is determined after 1-3 hours. After taking the pill (180 mg), the average maximum concentration is about 494 ng / ml, and with 120 mg, it is about 427 ng / ml.
Communication with plasma proteins varies between 60-70%, and the half-life of the drug after repeated administration is 12-15 hours.
We can not say that the drug in question is excreted along with breast milk. About 5% of the dose undergoes extrahepatic metabolism (partial).
The medication is removed mainly along with bile (about 80%), as well as through the kidneys unchanged (about 10%).
Indications for taking pills
What conditions of the patient may require taking the drug Fexofast 120? The instruction reports that the medication mentioned has a persistent antiallergic effect. In this regard, its use is recommended for:
- chronic urticaria;
- rhinitis seasonal allergic.
Contraindications to the use of the drug
Do you know what contraindications Fexofast tablets have? The instruction reports that there are not many prohibitions on this tool. It is not recommended to be taken only in the following conditions:
- breastfeeding;
- hypersensitivity to the main and auxiliary components;
- carrying a baby;
- in childhood (i.e. up to 12 years).
Particular care should be taken when treating people with chronic renal failure and other disorders in the functioning of the kidneys and liver.
Medication "Fexofast": instructions for taking tablets
How should I take Fexofast antiallergic? The drug in tablets is intended for oral administration in seasonal allergic rhinitis in adults and adolescents from 12 years.
The dosage of this agent should be determined only by a narrow specialist based on the data of analyzes and a medical examination. As a rule, with the aforementioned disease, the patient is prescribed a drug in the amount of 120 mg once a day.
In such a pathological condition as chronic urticaria, adolescents and adults are prescribed 180 mg of the drug once a day.
The duration of treatment is determined individually, depending on the severity of allergic manifestations and the patient's condition.
Adverse reactions
Can Fexofast 180 tablets cause side effects? The instruction reports that this drug rarely contributes to the development of unwanted effects. Sometimes patients complain of headaches, nausea, drowsiness, and dizziness.
It should also be noted that in rare cases, the medication in question can cause a feeling of fatigue, insomnia and other sleep problems, nervousness, as well as urticaria, skin rash, itching and other intolerance reactions.
Overdose symptoms
Before taking Fexofast 180 tablets, the instructions must be studied by the patient. It indicates the recommended and effective dosages of this drug, as well as the frequency of its administration.
If you exceed the indicated amount of the drug, then the patient may experience symptoms of overdose such as dizziness, dry mouth and drowsiness.
To eliminate such conditions, standard measures are taken to eliminate an unabsorbed drug from the gastrointestinal tract. Symptomatic and supportive therapy is also performed.
Other drug compatibility
The drug "Fexofast" is not subjected to biological transformation in the liver. In this regard, it does not interact with other medicines that undergo hepatic metabolism.
Experts have proved that when combining the drug in question with Ketoconazole and Erythromycin, the concentration of fexofenadine in the blood rises 3 times. This is due to an increase in the absorption of the drug from the gastrointestinal tract, as well as with a decrease in the excretion of bile and gastrointestinal secretion.
With the simultaneous administration of aluminum and magnesium-containing antacids, ÂĽ hours before taking Fexofast, a decrease in its bioavailability is observed. The interval between taking these drugs should be 120 minutes.
It should also be noted that Fexofast tablets do not interact with Omeprazole and drugs that are metabolized in the liver.
Analogues of the drug and its price
How much do Fexofast 120 tablets cost? Instructions for use do not answer the question. You can find it only in a pharmacy. You can buy this medication for 170-230 rubles.
As for similar drugs, they include such drugs: “Telfadin”, “Allegra”, “Fexofenadine”, “Allerfex”, “Fexadin”, “Gifast”, “Telfast”.
Patient Reviews
Now you have an idea of ​​how to use the drug “Fexofast”. Instructions for taking this medication have been described above.
Unfortunately, allergic reactions worry many people. To get rid of their manifestations, patients are often prescribed Fexofast tablets.
Most people leave only positive reviews about this medicine. They report that it is a highly effective drug that helps eliminate all allergic manifestations.
However, there are patients who claim that the drug in question provides only temporary relief.