FSH hormone, why is it elevated and lowered?

A huge amount of hormones is produced in the human body. Their endocrine glands are produced. Homons affect almost all processes occurring in the body. Violation of their balance can lead to serious pathologies.

One of them is infertility, which is often endocrine. The main culprit is the imbalance of sex hormones. Moreover, it leads to both female and male infertility.

Even if the amount of only one hormone is increased or decreased, this can adversely affect fertility. And since all elements of the endocrine system are interconnected, this will eventually lead to a complete imbalance.

Follicle-stimulating hormone (FSH) is produced in the pituitary gland. Its release into the blood occurs in portions after a few hours. Subsequently, the FSH hormone binds in men to Sertoli cells, in which the synthesis of androgen-binding protein is activated. This helps transport testosterone to the epididymis .

In women, the hormone FSH binds to the ovarian cell receptor apparatus. It stimulates the growth of follicles, preparing them for ovulation.

So, the hormone FSH performs the following functions in the body:

  • promotes the maturation and formation of germ cells;
  • affects the synthesis of estrogen (female sex hormones);
  • stimulation of the growth of the ejaculatory tubules;
  • an increase in blood testosterone levels, providing libido and sperm maturation;
  • effect on follicular formation, leads to ovulation.

Today, the level of this hormone can be determined in any modern laboratory. The analysis is given on the 5-7th day of the cycle or on the dates indicated by the doctor. In men, it can be determined at any time.

Three days before the analysis, do not physically strain. Do not smoke one hour before appearing in the laboratory. Blood is given on an empty stomach from a vein; before analysis, you should calm down and relax. More detailed instructions must be obtained from your doctor and laboratory. A study is performed during the day.

If the FSH hormone is elevated, then the following can be suspected:

  • seminoma;
  • renal failure;
  • x-ray exposure;
  • dysfunctional bleeding from the uterus (with persistence of the follicle) ;
  • testicular feminization;
  • Shershevsky-Turner syndrome, Swaer, ovarian exhaustion;
  • primary hypogonadism in men;
  • pituitary adenoma (basophilic);
  • ovarian cysts (endometrioid).

A decrease in its level occurs in the following cases:

  • contact with lead;
  • obesity;
  • surgical interventions;
  • starvation;
  • hyperprolactinemia;
  • Sheehan's syndrome, polycystic ovaries;
  • pituitary dwarfism;
  • Simmonds disease;
  • hypogonadotropic hypogonadism;
  • secondary amenorrhea.

An analysis is recommended in the following cases:

  • endometriosis;
  • growth retardation;
  • miscarriage;
  • checking the effectiveness of hormone therapy;
  • polycystic ovary syndrome;
  • dysfunctional uterine bleeding;
  • decreased potency and libido;
  • amenorrhea and oligomenorrhea;
  • infertility;
  • anovulation.

If the FSH hormone is elevated, it is impossible to prescribe a treatment immediately, since additional studies are needed. Most likely, the doctor will conduct a detailed survey of the patient and advise additional tests.

For example, the relationship with luteinizing hormone (LH) is important . 2 years after the onset of menstruation, it should be 1.5-2 times more FSH. It will be useful to pass on other hormones that affect fertility:

  • progesterone;
  • estradiol;
  • testosterone;
  • prolactin;
  • DEA sulfate.

The norms of FSH in mme / ml are as follows:

children 0.3-6.9;

males 1-11.9;

before ovulation, 1.8-11.4;

during her 4.9-20.5;

after ovulation, 1.2-9.6;

postmenopause 32-130.

Thus, FSH has a significant effect on the sexual function of both men and women. Its increased and decreased number may indicate serious pathologies.


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