"Wobenzym" refers to the category of systemic enzyme therapy drugs that are gaining popularity recently. The peculiarity of the drug lies in its anti-inflammatory and immunomodulatory effects in the treatment of many diseases. "Wobenzym" also reduces the negative effects of antibiotics and hormones as part of complex therapy. But in order to understand the principle of action of the drug, in which cases to use it and how to use it correctly, it is worth studying the instructions. And also to figure out which analogues exist.
"Wobenzym": release form and composition
The drug is available in the form of tablets. They have a biconvex shape with a smooth surface of bright red or orange. The medicine is packaged in transparent blisters of 20 pcs. The package contains from 2 to 20 plates. On sale you can also find the packaging of the medicine in plastic bottles of 800 pcs. in each. The release form of "Wobenzym" implies oral administration of the drug. The manufacturer of the drug is the German company Mucos Emulsionsgesellschaft mbH.
The active components of the drug are enzymes (eczema) of plant and animal origin. That is why the manufacturer claims that the drug is effective in the treatment of many diseases.
Eczymes are protein molecules that activate biological processes in the body. Their function includes: wound healing, protection against the introduction of pathogens into the body, cell renewal, microbial clearance and much more.
Enzymes that make up the drug:
- pancreatin;
- rutoside;
- papain;
- trimsin;
- lipase;
- bromelain;
- chymotrypsin;
- amylase.
The auxiliary components are: stearic acid, silicon dioxide, sucrose, talc, methacrylic acid, titanium dioxide, vanillin, wax, yellow-orange and crimson dye.
The properties
According to reviews and instructions, Wobenzym has a complex effect on the body.
Its effectiveness is based on the action of enzymes and affects the following processes.
- Inflammation. The drug regulates the development of the inflammatory process, by limiting the production of excess anti-inflammatory cytokinins, as well as the splitting of inflammatory mediators, which reduces tissue swelling. The drug prevents the transition of an acute form of pathology to a chronic one, and also reduces the frequency of relapses and their duration.
- Rheology. "Wobenzym" promotes blood thinning, prevents platelet adhesion, which reduces the likelihood of heart attack and thrombosis.
- Immunity. It activates the body's internal defenses, and also increases the production of interferons, which helps to increase local and general immunity.
- Metabolism. Reduces the level of harmful cholesterol and atherogenic lipids, activates cellular metabolism, which prevents the development of atherosclerosis.
The drug also has an additional effect:
- increases the bioavailability of antibiotics and stabilizes the intestinal microflora throughout the course of treatment;
- possesses antioxidant property;
- improves oxygen access to cells;
- relieves pain;
- reduces the likelihood of side effects when taking hormonal drugs;
- promotes quick recovery after stress;
- shortens the recovery period after surgery;
- prevents the formation of adhesive processes.
According to reviews and instructions for use, Wobenzym is not addictive, it does not inhibit the production of its own enzymes by the body, and is also well tolerated if long-term use is necessary, regardless of the patient's age category.
Pharmacokinetics
The tablet of the drug "Wobenzym" when it enters the body in transit passes through the upper sections of the digestive tract due to the protective membrane. The drug is absorbed in the small intestine, after which the enzymes enter the bloodstream and move to the area of inflammation.
The maximum concentration of active substances is fixed 2 hours after swallowing the tablet. This indicator persists for 4 hours, and decreases over the next two. The elimination half-life is 8 hours. 10% of the substances leave with urine, and 45% with feces.
General indications
"Wobenzym" is used as part of complex therapy in the treatment of a wide range of diseases.
The main ones are:
- thrombophlebitis;
- atherosclerosis;
- obliterating endarteritis;
- diabetic angiopathy, retinopathy;
- pyelonephritis;
- autoimmune thyroiditis;
- atopic dermatitis;
- acne;
- Ankylosing spondylitis;
- subacute stage of heart attack;
- bronchitis;
- pneumonia;
- sexually transmitted infections (chlamydia, ureaplasma, mycoplasma);
- sinusitis;
- reactive arthritis;
- recurrent phlebitis;
- injuries, fractures, bruises;
- pancreatitis
This is not the whole list of pathologies for the treatment of which Wobenzym is used. A special place is given to the drug in the treatment of gynecological diseases.
The use of Wobenzym in gynecology helps to eliminate the following health problems:
- adnexitis or inflammatory process in the uterus and appendages;
- endometritis;
- colpitis;
- atropic vaginitis;
- cervical dysplasia;
- chronic cervicitis;
- infertility on the background of a recurrent form of inflammation of the ovaries, fallopian tubes;
- impaired vascular function during menopause;
- recovery period after abortion, curettage;
- mastopathy
- promenstrual syndrome.
The use of Wobenzym in gynecology prevents the development of adhesions and the formation of keloid scars, which makes it difficult to fertilize the egg. And also minimizes the likelihood of developing an ectopic pregnancy and general reproductive dysfunction.
Can it be used for diabetes?
The use of "Wobenzym" in diabetic retinopathy can reduce puffiness and restore microcirculation in the eyeball, and the drug also helps to resolve hemorrhages in the fundus. This feature favorably affects the function of the organs of vision and improves color perception.
With a diagnosis of diabetic angiopathy, the drug improves the sensitivity of the limbs, normalizes the blood microcirculation in them, and also reduces the level of bad cholesterol in the body. Due to this, the feeling of weakness and burning sensation in the legs disappears, cramps appear less and less, swelling decreases. The distance of painless walking is increased by 2 times.
Contraindications
The drug can not be used with individual hypersensitivity to one of the components that make up its composition.
The feature of "Wobenzym" to prevent platelet adhesion makes it impossible for patients suffering from pathologies characterized by an increased likelihood of bleeding (thrombocytopenia, hemophilia).
The drug is also contraindicated in patients with impaired renal function, requiring hemodialysis.
The age limit for admission is the age of 5 years.
Instructions for use
The tablet release form of Wobenzym is used in combination with other drugs that have a directed effect on the main cause of the pathology. Dosage and administration are prescribed by the attending physician, depending on the established diagnosis and form of the disease.
Drink the medicine should be whole, without violating the integrity of the upper protective shell. Reception is carried out in 30 minutes. before the main meal or 2 hours after that. It is recommended to drink the drug with clean water at least 250 ml.
The standard dosage of the tablet form of release "Wobenzima:
- For adults. Start therapy with taking 3 tablets 3 times a day. Adhere to this regimen for the first 3 days. Then, according to the results of the analyzes, the daily norm of the drug is 5-10 tablets three times a day for 1 month. In the next 4-8 weeks, the drug should be taken at the rate of 3 tablets three times a day.
- To the children. The drug is taken at the rate of 1 tablet per 6 kg of the child's weight. The daily rate is taken 3-4 times through equal time periods. At the beginning of the course, it is recommended to drink Wobenzym in small portions, but more often. The duration of therapy is indicated by the doctor, depending on the identified pathology and individual characteristics of the child.
For the treatment of female diseases, the course and dosage of the medicine are slightly different from the standard scheme.
We decided to present the instruction on the use of Wobenzym in gynecology for better perception in the form of a table.
| Diseases | Daily rate | Course duration |
| Acute form of inflammation | 5-8 pcs. 3 times a day | 2 weeks |
| Chronic inflammatory process | 5 pcs. 3 times a day | 2-3 months |
| Endometriosis | 5 pcs. 3 times a day | 2 months |
| Thromboembolic complications | - first 3 weeks - 7 pcs. 3 times a day;
- next 4 weeks - 5 pcs. 3 times a day;
- in the future - 3 pcs. 3 times a day
| at the discretion of the attending physician |
According to the instructions, "Wobenzym" in gynecology when combined with antibiotics, to enhance the effect of the latter, 5 tablets are prescribed three times a day. This regimen is observed throughout the use of antibiotics. After this, Wobenzym therapy is continued for 3 tablets three times a day for 2 weeks. This avoids dysbiosis and helps restore normal intestinal microflora.
special instructions
At the beginning of therapy, exacerbation of unpleasant symptoms is possible. This is not a reason to cancel Wobenzym. It is recommended in this case to reduce a single dosage, but it is impossible to stop therapy.
The components of the drug do not affect the psychomotor function, so during the period of therapy it is not forbidden to drive a car, as well as perform work requiring a high concentration of attention.
Side effects
The drug is well tolerated by patients of different ages. Even with prolonged use of the drug, no side effects have been identified.
But the manufacturer, in the annotation to the remedy, indicates that the drug can cause:
- nausea
- urticaria;
- a feeling of heaviness in the stomach;
- change in stool odor;
- itching on the skin;
- rash.
All unpleasant symptoms caused by taking "Wobenzym" disappear on their own at the end of therapy.
If the side effects are persistent, which negatively affects the quality of life, it is necessary to consult a doctor about stopping the medication.
Interaction with other medicines
Cases of drug incompatibility with other types of drugs have not been identified, on which the manufacturer insists.
When the drug is combined with antibiotics, it enhances their effect, and when interacting with hormonal drugs, it reduces the severity of side effects.
Analogs
The only Wobenzyme analogue is Phloenzyme. The active components of the drug are enzymes - rutin, trypsin, bromelain. According to the instructions, the analogue of "Wobenzym" is prescribed as part of complex therapy for prolonged chronic inflammation during periods of exacerbation. Its action is also used to treat diseases of the upper respiratory tract, genitals, rheumatism, coronary disease, multiple sclerosis.
Instructions for use of the analogue of "Wobenzym":
- standard dosage - 2 times a day for 3 tablets;
- maximum dosage - 4 times a day for 3 tablets.
Drink the medicine with plain water at least 200 ml per 1 dose. Duration of admission is 2 weeks, unless otherwise specified by a doctor.
Reviews
Reviews about the analogue of "Wobenzym" and the drug itself are very controversial. Negative are mainly based on the lack of a full evidence base for the effectiveness of the drug. In addition, as the drug "Wobenzym" is registered only in Russia, and in the USA and European countries it belongs to the category of dietary supplements.
But judging by the reviews of doctors, the versatility of the drug allows it to be used to treat many diseases, and the unique composition helps accelerate recovery and minimizes the likelihood and duration of relapses. Therefore, positive reviews about the use of Wobenzym are much more common. But how effective the drug and its analogue can be determined in each case only by an experienced specialist, depending on the individual characteristics of the patient and the severity of the pathology.