Improper nutrition, taking certain medications, alcohol abuse - all this extremely negatively affects the condition of the liver. Over time, if a person does not reconsider his lifestyle, chronic organ diseases develop that sooner or later lead to cirrhosis. And this, in turn, is a fatal and incurable disease. The use of the drug "Karsil" can stop the pathological processes of fatty degeneration of liver cells and even start the process of partial regeneration. The speed of organ recovery largely depends on what lifestyle the patient adheres to: does he follow a special diet, has he abandoned bad habits.
The composition and form of the drug
"Karsil" refers to the pharmacological class of hepatoprotectors - drugs that are taken to prevent liver diseases and restore hepatocytes with existing diseases. The composition of the drug is herbal, so taking "Karsil" extremely rarely causes side effects.
The main active ingredient is dry extract of the fruits of milk thistle (silymarin). One tablet contains 35 mg of this substance. Excipients are also used: microcrystalline cellulose, lactose monohydrate, wheat starch, povidone (colidone 25), magnesium stearate, talc, dextrose monohydrate, sodium bicarbonate.
In addition to tablets (dragees), there is also such a form of release as capsules. One capsule contains a larger amount of silymarin - 163.6-225 mg. Capsules are called "Carsil Forte", and dragees are simply called "Carsil". Treatment, regardless of which form of release of the drug is preferred, will be equally effective. Both options are a worthy tool both for the prevention of liver diseases, and for the elimination of existing pathologies.
Indications for use of the drug "Karsil"
The use of the drug is justified for a variety of liver diseases. The instruction reports that the indications for use are as follows:
- liver damage of alcoholic etiology;
- reduction of the toxic load on the body due to poisoning and medication;
- reduction of the load on the liver with cirrhosis if the patient does not follow the diet;
- fatty hepatosis;
- violation of the outflow of bile (liver disease, accompanied by chronic cholecystitis).
Whatever the diagnosis, the use of Karsil is always oral. Dragees can not be chewed or divided into parts - this can lead to a violation of assimilation.
pharmachologic effect
What is Karsil for patients with liver pathologies for? It is known for certain that the effectiveness of silymarin (the main active component of the drug) is manifested due to its ability to interact in the membrane of liver cells with receptor complexes. This leads (subject to regular use) to normalize the functions of the membrane itself. As a result, the processes of the formation of fatty degeneration and fibrosis are inhibited. The action of "Karsila" can be strengthened many times if the patient adheres to the course of treatment of a healthy diet (medical table No. 5).
The main active ingredient "Karsila" is involved in the regulation of cellular metabolic and other processes by adjusting the permeability of cell membranes. Reduces the pathological effects of free radicals. It normalizes metabolism in already damaged cells, contributing to the restoration of the organ, and also exhibits an antioxidant effect. It should be noted that there is only one way to use Karsil - oral, that is, dragees should be swallowed and washed down with water.
Contraindications to the use of "Karsila"
Instructions for use report that a contraindication to use is a state of acute intoxication in a patient. Also, the drug is forbidden to use for the treatment of children whose age has not reached five years.
As for the treatment of women during pregnancy and lactation, the method of use of "Karsil" does not differ from the usual one - the dosage and duration of treatment are the same. But before you start taking it, you should consult your doctor.
An absolute contraindication to use is intolerance to silymarin or other components that make up Karsil.
Possible side effects
Subject to the rules of administration, the drug is usually well tolerated. However, in some cases, the patient experiences nausea and weakness after taking the capsules. In this case, you should try taking dragees, since the concentration of the active substance in them is lower.
If even after a dragee the state of health leaves much to be desired, then a different hepatoprotector should be selected. Most likely, the patient has an individual intolerance to silymarin.
Recommended dosage of the drug and method of use
The instruction warns that both tablets and dragees should be taken whole, without separating with a knife and without chewing. Drink a little clean water. There is no evidence that silymarin is better absorbed in parallel with food intake. You can take a dragee or capsule, regardless of the meal time.
The dosage of “Karsila” for pathologies of the state of the liver of the lung of moderate or moderate severity is 1-2 tablets (22.5-45 mg) three times in 24 hours. In severe situations, it is possible to increase the dosage by two or even three times, while maintaining the frequency of doses.
Interaction "Karsila" with other medicines
It should be noted that when taking "Karsil" in parallel with some oral contraceptives, their effect decreases. In this case, the method of using the drug is as follows: daily intake at a therapeutic dosage, while oral contraceptives should be temporarily abandoned. Otherwise, an unwanted pregnancy may occur.
The drug enhances the action of antipsychotics and tranquilizers. Therefore, you should consult with your doctor about the need for therapy with these medicines. Pills are often prescribed in this order: in the morning - “Karsil”, and before bedtime - a dosage of psychoactive drugs selected experimentally.
Causes of the development of pathological processes in the liver
To achieve maximum treatment effectiveness (the method of using "Karsil" was described above), you should follow a diet, maintain a healthy lifestyle. Otherwise, spending on hepatoprotectors may be in vain. Most often, the following factors are the causes of the development of liver pathologies:
- improperly composed diet in which fats predominate;
- alcohol abuse;
- forced intake of hepatotoxic drugs.
Against the background of treatment with hepatoprotectors, to which Karsil also belongs, fatty foods should be excluded from the diet as well as alcoholic beverages should be excluded. If it is not possible to refuse to take hepatotoxic drugs, it is worth discussing with your doctor their replacement with softer drugs.
"Karsil" for the prevention of liver pathologies should be taken if the patient can not refuse to drink alcohol. Such a bad habit (although narcologists qualify it as addiction) will inevitably sooner or later lead to the onset of fatty degeneration of liver cells. To prevent this, hepatoprotectors should be taken for prevention. However, the best guarantee that the pathological processes do not start in the liver is a complete rejection of drinks with ethanol in the composition.
Compatibility "Carsila" and alcohol
Against the background of treatment with Karsil, alcohol consumption should be abandoned. If, for one reason or another, the patient is unable to refuse to drink alcohol during therapy with hepatoprotectors, then the effectiveness of treatment may be reduced or completely absent. It is important to understand that our liver is the first to take the “blow” on the breakdown of ethyl alcohol metabolites. As a result, this body suffers more than others. Almost all alcohol drinkers sooner or later develop chronic liver disease.
It does not matter what kind of drinks the patient prefers - whether it is beer or strong alcohol. All contain ethyl alcohol, which is extremely damaging to liver cells.
Patient reviews on the action of "Karsila"
The liver is an organ in which there are no nerve endings, so it does not hurt until the disease (whether it is fibrosis, hepatosis or toxic hepatitis) passes into the final stages. Over time, the patient feels heaviness in the right hypochondrium. But it does not indicate that it is the liver that hurts. As a rule, an organ increases in size and begins to choke on adjacent organs. As a result, the patient feels discomfort in the right hypochondrium. In addition, the skin begins to itch, the outflow of bile is disturbed, in the morning the patient often experiences a bitter aftertaste in his mouth, after eating, suffers from heartburn.
Reviews of “Karsil” report that one to two weeks after the start of taking the symptoms, signaling the presence of liver pathologies, are alleviated. Itchy skin and heaviness in the right hypochondrium go away. But there are negative reviews about the drug. In them, people say that they did not feel any effect, and liver tests performed after a course of treatment did not show an improvement in the clinical picture. In this case, a more powerful drug with a hepatoprotective effect should be selected. Often, negative reviews about Karsil are related to the fact that the patient did not revise his diet during therapy and continued to consume unhealthy fatty foods and alcohol.