The drug "Enalapril" is considered a fairly common drug used in the treatment of heart failure, hypertension, as well as nephropathy (diabetic). The medication has a lasting effect when used only once a day. The drug "Enalapril" is able to prevent myocardial hypertrophy, cause its reverse development.
The medicine is available in the form of injections and in tablet form.
Describing the drug "Enalapril", the instruction indicates its ability to reduce the total resistance of peripheral vessels, reduce the load on the myocardium. By reducing blood pressure, the drug, as a rule, does not provoke any changes in the frequency of contractions (reflex tachycardia) and minute volume.
The drug "Enalapril" helps to reduce pressure in the pulmonary circulation and the right atrium, and reduce hypertrophy of the left ventricle.
The medication is able to reduce the sensitivity of the heart to ischemic damage and the frequency of ventricular arrhythmias. In a post-infarction state, the drug is able to reduce the formation of myocardial necrosis (necrosis), increase metabolic processes.
I found the drug "Enalapril" application in the treatment of renovascular and different stages of essential hypertension. Prescribing the drug to patients with moderate or mild hypertension leads to a decrease in blood pressure when standing and lying down, and while standing, the drug does not provoke the development of orthostatic hypotension, does not affect cardiovascular reflexes, does not change the frequency of contractions.
The medicine "Enalapril" the instruction allows for use both as a single drug at the beginning of therapy, and as part of a combination treatment with other drugs for pressure, in particular, diuretics.
The antihypertensive effect after oral administration is noted, as a rule, after an hour, the maximum effectiveness is usually achieved after four to eight hours. The effect of the drug persists (when using the recommended therapeutic dosages) for at least twenty-four hours. As clinical practice shows, the optimal treatment result develops in the first or second week of the use of Enalapril.
After intravenous administration, the effect is noted after five to fifteen minutes. Maximum efficiency is observed after 1-4 hours. The duration of action lasts about six hours.
The drug "Enalapril." Instruction Contraindications
Do not prescribe medication for hypersensitivity, porphyria (hereditary metabolic disorder), primary hyperaldosteronism (an excess of the adrenal hormone), pregnancy, childhood, with stenosis (narrowing) of the mitral or aortic valve, hypertrophic cardiomyopathy, during lactation.
Means "Enalapril". Instruction Dosage
Therapy is carried out for a long time, in some cases throughout life.
The dosage of the drug is adjusted according to the patient's condition. Enalapril Acry is recommended to be taken before, during or after a meal. The tablets are not chewed, swallowed whole, washed down with water (in sufficient quantity).
After the first application, it is necessary to monitor the patient's condition with frequent measurement of blood pressure for several hours. With a high likelihood of hypotension, the patient should give the first dosage in a hospital setting and observe the condition for at least five hours. In this case, the patient should remain in a prone position.
Before using the drug "Enalapril", you must familiarize yourself with the annotation.