"Biotredin" is a drug that is used to treat alcohol dependence. It is used for adults, children under 15 years of age are contraindicated, should not be used in the treatment of lactating and pregnant women. Also, you should not prescribe it if the patient is intoxicated, takes medications that can suppress the functionality of the structures of the central nervous system. Reviews about "Biotredin" are abundant.
Pharmacological forms
The manufacturer produces the drug in a single pharmacological form - tablets, which are shown to be placed under the tongue. The Biotredin tablet is round, its surface is cylindrical, with a bevel, the color is white or with a faint shade of yellow. They are packaged in contour packaging with cells, each of which holds 30 tablets. One cardboard box contains one contour packaging, accompanied by instructions for use.
Composition, description
Biotredin contains two active components: L-threonine in an amount of 100 mg (in each tablet) and pyridoxine hydrochloride in an amount of 5 mg (in each tablet).
As auxiliary ingredients are used: citric acid, low molecular weight povidone, monohydrate, magnesium stearate.
Pharmacological group
In the presence of pyridoxine hydrochloride, L-threonine is able to convert to acetaldehyde and glycine, which is an amino acid. These compounds activate the inhibition processes and, at the same time, improve redox reactions, ATP synthesis and intracellular respiration. As a result, the following effects can be observed:
- Mental performance improves.
- Psychoemotional stress decreases.
- The level of endogenous acetaldehyde is normalized, against which there is a relief of withdrawal symptoms.
- Short-term and long-term type memory improves.
According to the instructions for use, Biotredin is able to exert a metabolic, neuroprotective, anti-withdrawal, anti-alcohol effect that develops 20 minutes after the tablet is used. The active components that are part of the drug are absorbed through the mucous membranes of the oral cavity quite quickly, thereby penetrating the systemic circulation. Then they spread to the structure of the central nervous system, where they begin to take part in the metabolism and therapeutically affect.
Indications
The main indications of Biotredin are:
- Therapy of withdrawal symptoms accompanying chronic alcoholism.
- Normalization of the functionality of the central nervous system in adolescents and adults, if there is a decrease in the ability to concentrate.
For adult patients, the medicine is prescribed in order to improve the ability to concentrate, as well as mental performance, which worsen as a result of overwork or various pathological processes.
As indicated by the instructions for use, "Biotredin" is also used for people with chronic alcoholism, if it is necessary to actualize the craving for alcohol, accompanied by affective disorders (mood decline, internal discomfort, increased irritability, aggressiveness). The drug is indicated for use with the aim of detecting and treating latent alcoholism, with withdrawal symptoms.
For children, the drug is allowed for use from the age of 15. It is indicated with a deterioration in the functionality of the central nervous system, a decrease in the ability to concentrate and the level of mental performance.
The drug cannot be used by nursing and pregnant women.
What else does the instructions for use of Biotredin tell us?
Contraindications
The medication has a number of contraindications, in the presence of which its use becomes impossible. Among such contraindications:
- Pregnancy of the patient, period of breastfeeding. However, the possibility of using the drug is allowed by specialists in cases where a woman drinks alcohol in such quantities that it can cause significant harm to the fetus.
- Individual hypersensitivity to any component that is part of the medication.
- The state of intoxication.
- The parallel use of medications that are able to suppress the activity of the central nervous system structures (anxiolytics, antipsychotics, antidepressants.
Contraindications "Biotredina" should be strictly observed.
Usage, dosage
The tablet preparation is intended for sublingual use. That is, tablets should be placed under the tongue and kept there until they completely dissolve. The use of the drug can be made regardless of meals. It is also possible pre-grinding tablets with further placement of the resulting powder under the tongue. In this case, the substance dissolves faster, respectively, the active components enter the systemic circulation faster.
The average therapeutic dose of the drug "Biotredin" in adult therapy depends on the indications for its use:
- With alcohol withdrawal, it is recommended that you take 3-4 doses during the first day. At each dose, up to 4 tablets can be used. From the second day of therapy, it is recommended to use a maintenance dose, which corresponds to 1-2 tablets, which should be taken twice or three times a day. The average course of therapy involves taking pills for 21 days.
- In case of chronic alcoholism or in the case when the patient is abusing alcohol, he is shown to take twice or three times up to 3 tablets per day. Courses last up to 5 days, can be repeated up to 10 times a year.
- With reduced mental performance, it is recommended to take twice or three times one tablet per day. The duration of therapy can be up to 10 days or less. If necessary, a repeat of the course of therapy is allowed up to 4 times a year.
The highest therapeutic effectiveness of the drug can be achieved by combining its administration with Glycine, which has a dosage of 100 mg. Most often, experts recommend taking it 15 minutes before taking Biotredin.
In adolescence, a medication can be used to normalize the functionality of the central nervous system structures, as well as if you need to increase concentration and mental performance. In this case, the patient is prescribed a three-time intake of "Biotredin" per day in an amount of up to 2 tablets. Use the product for several days, if necessary, a similar short course can be repeated up to 4 times a year.
It is allowed to use the drug during lactation, during pregnancy for women who have chronic alcoholism. However, such use is permitted only in the presence of strict medical indications. The dosage should be determined by the doctor taking into account individual indicators.
This is confirmed by the instructions for use of Biotredin.
Negative impact
Most often, the drug is well tolerated by patients, however, against the background of its use, some side effects can still develop, such as:
- Excessive sweating.
- Allergic skin reactions, expressed in rash, itching, angioedema shock. They develop if the patient has hypersensitivity to pyridoxine.
- Dizziness.
If such symptoms appear, the patient should consult with a specialist and discuss the feasibility of further use of the drug.
Interaction with other medicines
With the simultaneous use of "Biotredin" with drugs that can inhibit the functionality of the central nervous system, the therapeutic effectiveness of the latter is reduced. Thus, the medication is incompatible with anxiolytics, antipsychotics, barbiturates, antidepressants. If the reception of these funds is necessary, before combining the drugs, you should definitely consult with your doctor.
Currently, clinical practice does not have data on registered cases of overdose of Biotredin.
Special instructions for use
Before starting therapy, it is important to pay attention to the fact that there are a number of special instructions that should be observed when taking Biotredin. Among them:
- For the entire time the medication is used, the patient must abandon the activities associated with complex mechanisms and driving.
- When prescribing the drug to lactating and pregnant patients, strict indications and a confirmed diagnosis in the form of chronic alcoholism should be available. Taking the medicine, despite its toxicity to the fetus, is permissible in such cases, since alcohol in large doses provokes significantly greater intoxication.
- In a state of intoxication, tablets should not be taken due to a significant decrease in their therapeutic effectiveness.
Analogs of Biotredin
Today, Biotredin is a unique preparation in its composition and has no structural analogues. However, there are products on the market that can have a similar therapeutic effect. Among them:
- Antaxon The pharmacological form of this drug is capsules intended for oral administration. The active components of the drug are able to competitively bind to opiate receptors located in the structures of the central nervous system. As a result, the patient is depressed by the feeling of euphoria from the use of psychoactive substances. Most often, "Antaxon" is used by specialists if there is a need for treatment of alcohol and opiate addiction. For women during pregnancy, during breastfeeding, for children, the drug is strictly contraindicated.
- Colme. A drug used as a component during complex therapy. Pharmacological form - drops intended for oral administration. It can be used exclusively for adult patients. For women during pregnancy, during breastfeeding, for children, the drug is strictly contraindicated.
The feasibility of replacing the medication should be determined by the doctor.
Cost
In Russian pharmacies, the average cost of a medication is at the level of 125 rubles and can range from 88-167 rubles. The price varies depending on the region of distribution and the pricing policy of the pharmacy chain.
Reviews
Experts consider it a safe drug. With its help, you can do without the use of potent antidepressants, which have an extensive number of negative effects.
According to reviews, Biotredin is very effective in the treatment of children, who, against the background of its use, begin to better absorb the material, become more diligent, assiduous. At the same time, an improvement in mood is noted. The greatest effect is achieved by combining funds with "Glycine."
Separately, a small number of negative effects of the drug developing on the background of its use, a very affordable price, ease of use and high effectiveness in withdrawal symptoms were noted.
Despite the effectiveness, safety of the drug and the presence of good recommendations, the appropriateness of its administration should be determined by the doctor.