The drug "Longidaza" (suppositories) is intended for rectal or intravaginal administration. The tool has a proteolytic activity of prolonged (long) action. The medication has an immunomodulatory, antioxidant, chelating and anti-inflammatory (moderate) effect. With the introduction of rectal absorption into the systemic circulation occurs quite quickly. The drug reaches its maximum concentration after an hour. The bioavailability of the drug is about 70%. The medication "Longidaza" (suppositories, reviews of experts confirm this) is characterized by a high rate of distribution to organs and tissues. The medicine passes the BBB. Excretion is carried out to a greater extent by the kidneys.
Application
Candles "Longidaza" is used in urological practice. Indications include chronic prostatitis, interstitial cystitis, Peyronie's disease, ureteral stricture and urethra. The medicine is recommended for the prevention of scarring and the formation of strictures after surgery on the bladder, urethra, and ureter. The drug "Longidaza" (suppositories) (expert reviews confirm this) helps to reduce the manifestations of benign prostatic hyperplasia at the initial stage. In surgery, the medication is indicated for long-term non-healing wounds, for the treatment and prevention of adhesions after operations on the peritoneal region. Longidase suppositories are used in gynecology for tubal-peritoneal infertility, intrauterine synechia, and chronic endomyometritis.
The medicine is prescribed for the treatment and prevention of
adhesions in the pelvic area after surgical procedures (abortions, other interventions), for diseases of the internal organs of the chronic course. Means are indicated for use in phthisiology and pulmonology. The drug "Longidase" (suppository) is prescribed - reviews of experts confirm this - with siderosis, pneumofibrosis, pleurisy,
interstitial pneumonia, tuberculosis.
Contraindications
Not recommended for pregnancy, hypersensitivity. Not prescribed a drug under the age of twelve years, in the presence of malignant neoplasms, hypersensitivity. Caution during therapy or prevention should be observed in patients with renal failure, with anamnestic data on pulmonary hemorrhages.
Dosing method
The drug "Longidaza" (suppositories) - reviews of doctors indicate this - it is recommended to use rectally after bowel movement. As a rule, it is prescribed by suppository at night (intravaginally or in the rectum). One course involves ten to twenty introductions. Depending on the tolerance, severity of the disease, the age of the patient, the treatment regimen may be adjusted. So, the drug can be used every other day or with an interval of two to three days.
Adverse reactions when using the drug "Longidaza" (candles)
Patient reviews indicate satisfactory tolerance to the drug. In some cases, the development of allergic reactions is likely. As a rule, they are caused by the presence of hypersensitivity to the components. If these side effects occur, consult a doctor.