“Bergolac” - a drug belonging to dopamine receptor agonists and containing cabergoline, the main substance of the drug, derived from ergoline. "Bergolak" overwhelmingly affects the process of isolation of prolactin. As a result of its intake in the blood, the level of prolactin decreases, fertility is restored and menstrual irregularities are eliminated. Acting on men, the drug reduces the severity of some manifestations of hyperprolactinemia.
Pharmacokinetics
There is good absorption and uniform distribution after using Bergolak. Reviews show that food intake has no effect on these indicators. According to the instructions, the highest concentration of the drug is present in the blood plasma after an average of 2.5 hours, while the main component binds to its proteins by 41-42%.
The body is an active metabolism of "Bergolak." Substances formed as a result of this process are excreted by the intestines (approximately 72%) and the kidneys (approximately 18%). In the composition of urine, 2-3% of the active ingredient is present unchanged.
Indications for use
The medicine is prescribed for pituitary tumors and female infertility. High efficiency in cases of menstrual irregularities is reflected in the reviews left after treatment with Bergolak. Termination of lactation as a result of taking this drug is also possible. The need to suppress this process may arise after abortion and childbirth. Lactation can not only be suppressed, but also prevented.
"Bergolac" allows you to eliminate the violations that arose as a result of hyperprolactinemia. Indications for the use of the drug are prolactin- secreting pituitary adenoma, idiopathic hyperprolactinemia. Based on the drug “Bergolak”, treatment of patients with the syndrome, which is called the “empty Turkish saddle” and is enhanced by hyperprolactinemia, can be carried out.
Particular care is required during the period of treatment when bearing a child and breastfeeding. Acceptance of funds for patients with impaired liver function should be carried out under the supervision of a doctor.
Contraindications
The instruction left about the Bergolak remedy, reviews of doctors show the presence of such contraindications:
- hypersensitivity to components;
- children's age (less than 16 years);
- insufficient absorption of glucose and galactose;
- hereditary galactose intolerance in forms that are rare;
- congenital lactase deficiency;
- psychosis that occurs after childbirth;
- breathing problems, disturbances in the work of the heart, as a result of fibrotic changes in the body, including a history of;
- persistent increase in blood pressure, uncontrollable.
In the treatment of the elderly, the drug should be taken with caution. The same goes for patients with a diseased liver.
Drug use, dosage
As the reviews left after taking the Bergolac remedy show, lactation can be prevented or interrupted. Depending on the task, the dosage is:
- before the development of lactation - 1 mg of the drug, which corresponds to two tablets, which must be consumed at one time after the birth of the baby (the next day);
- after its development - 0.25 mg, which corresponds to half the pill, which should be taken two days with a frequency of 12 hours.
In the presence of other indications, doctors usually prescribe Bergolak patients at a dose of 0.5-1 mg once or twice a week. The maximum allowable weekly rate is 4.5 mg of the drug. At the same time, it is impossible to switch sharply to the maximum dose, only gradually by increasing it by 0.5 mg monthly, if necessary. The medicine is taken orally with food.
Patients using Bergolak, reviews to reduce prolactin with hyperprolactinemia leave mostly positive. Disorders caused by this process are treated by applying an initial weekly dose of 0.5 mg. It is possible to divide this dose into two doses of 0.25 mg of the drug. In this case, the drug can be used twice a week.
Lactating women are usually prescribed medication so that at one time no more than 0.25 mg of the drug enters the body. Thus, it is possible to exclude the number of possible adverse reactions.
The therapeutic dose intended for use in one week, most often is not more than 2 mg. Although everything is individual and for each patient, the doctor selects an individual treatment option.
Women who used Bergolac during pregnancy leave reviews with information on the need for careful use of the drug. In such periods of life, its use is carried out under regular medical supervision and only at the doses recommended by it. Despite the fact that it is not recommended to use tablets for pregnant women, in cases where the benefit to the mother's body significantly exceeds the possible risks to the fetus, this is permissible. Breastfeeding during therapy with "Bergolac" is stopped.
Side effects
Undesirable reactions can be different, and their severity may also vary. In most cases, all unpleasant manifestations disappear on their own after 14 days of therapy or after a certain time after refusing the drug.
Judging by the fact that the reviews left as a result of treatment with the Bergolak medication show the likelihood of dizziness, drowsiness and weakness, the general state of health can sometimes worsen.
There is a risk of skin allergies. Pallor of the skin as a result of exposure to cold is possible. Changes in the functioning of the gastrointestinal tract, for example, constipation, nausea, may be noted. Other side effects include nasal congestion, drying out of the oral mucosa.
Drug interaction
We will find out if Bergolak tablets can be used for combined treatment. Reviews of doctors show that with prolonged therapy, the drug should not be used together with ergot alkaloids, their derivatives.
It should be borne in mind that some antagonists of dopamine receptors can adversely affect the effect exerted by cabergoline, and macrolides can increase the level of the active substance of the drug “Bergolak” in the blood. Alcohol makes the drug less effective.
Medicines, the action of which is aimed at lowering blood pressure, is prescribed with caution during therapy.
special instructions
If conception is planned, it is permissible only after a certain time after completion of therapy, usually after a month. "Bergolac" is taken only after a thorough examination of the pituitary gland. During therapy, the state of the body should be constantly monitored.
While treatment is underway, it is not recommended to drive a car and other vehicles, to engage in activities that require quick reactions and increased care. It is very important to adhere to all the recommendations of a doctor.
Cost, reviews
For many people planning to take Bergolak, price, reviews - this is always information that contains a lot of useful information, allows you to know in advance the cost of the drug, the treatment features and possible undesirable reactions that patients encounter during therapy, to check its effectiveness .
The approximate cost of tablets (2 pcs. At 0.5 mg) is 235-260 rubles. As for the use of Bergolac in order to stop lactation or prevent it, judging by the reviews, the drug does not always cope well with these tasks. But when using the drug for hypoprolactinemia, many note the achievement of the necessary effect. However, there is a risk of side effects of the drug, which some people notice at their initial stage of treatment.
Many are pleased with the quick action and low cost of the drug in comparison with other similar drugs. Of the side effects, constipation, drowsiness, and a slight headache are sometimes noted.