An agent called "Tranexamic acid" is an antifibrinolytic drug that has anti-inflammatory and anti-allergic effects, as well as a pronounced hemostatic effect in bleeding, which is associated with increased fibrinolysis. The basis of this drug is the inhibition of plasminogen activator and plasmin, the suppression of the formation of active peptides and kinins, which are directly involved in inflammatory and allergic reactions. In addition, a tool such as Tranexamic Acid significantly prolongs thrombin time. As for the pharmacokinetics of this antifibrinolytic drug, about 30-50% of its initial dosage is absorbed after ingestion, while the highest plasma concentrations are observed one hundred to one hundred and eighty minutes after use. The antifibrinolytic effect in the tissues lasts for fifteen to seventeen hours, and in the plasma for seven to eight hours after the use of the Tranexamic Acid drug. The price of this tool is about 1,300 rubles, and you can purchase it in almost every pharmacy.
An antifibrinolytic drug is produced in the form of tablets of two hundred fifty or five hundred milligrams, in the form of a solution for injection, as well as in the form of a solution intended for oral administration. All of these dosage forms are excellent for the treatment and prevention of bleeding, provoked by an increase in general fibrinolysis. For example, a remedy referred to as Tranexamic acid is often prescribed for malignant neoplasms of the prostate or pancreas, leukemia, surgical interventions on the chest organs, and liver diseases.
Manual separation of the placenta and postpartum hemorrhage are also included in the list of indications for use. In addition, the drug "Tranexamic acid" should be used for hematuria, angioedema, allergic dermatitis, eczema, toxic and drug rash, urticaria. In addition, this drug is actively prescribed for pharyngitis, laryngitis, tonsillitis, stomatitis, nose, uterine and
gastric bleeding, tooth extraction in patients with a diagnosis of
hemorrhagic diathesis. A remedy such as Tranexamic Acid also helps with menstruation, characterized by abundant secretions.
As for the features of the use and dosage of the drug, in each case they are set individually, based on a particular clinical situation. However, as a rule, no more than 1–1.5 grams are allowed to be taken orally. Moreover, the frequency of use is from two to four times a day, and the duration of treatment is from three to fifteen days. A single dose for intravenous administration is 10-15 mg / kg.
The main contraindications to the use of this drug are conditions such as subarachnoid hemorrhage, thromboembolic syndrome, renal failure, impaired color perception and deep vein thrombosis. In addition, this drug should not be used in case of increased individual sensitivity or pregnancy. Side effects associated with taking this antifibrinolytic agent are manifested in the form of dizziness, drowsiness, hypotension, tachycardia, weakness and pain in the chest.