Varicose veins are unusually widespread. Based on statistics, signs of the disease were found in approximately 90% of women and 65% of men. Pathology is not selective for age, and it is increasingly detected in schoolchildren.
The pharmaceutical industry is actively studying the development and production of drugs for the prevention and treatment of varicose veins. Among the many medications, the rutoside preparation deserves special attention. Despite the fact that it has been used for a long time, it is not considered obsolete and is often prescribed by doctors.
What is rutoside?
A similar substance was first obtained in 1842. Rutoside is an organic compound of plant polyphenols belonging to the group of vitamins P. In nature, such a flavonoid is widespread. Of the vegetables that are often used by people, it is most found in tomatoes, bell peppers, sorrel, cabbage. Its largest content in the berries of chokeberry - in 100 g of juice, about 2 thousand mg.
Vitamin is also found in citrus fruits, as well as in many berries and fruits: cherries, apples, apricots, plums. Blackcurrant, blueberries, rose hips, blackberries also have a similar substance.
Sophora is a rutoside derived from Japanese Sophora. Most often, the substance is extracted from buckwheat. Rutoside's relevance to plants boils down to providing protection against ultraviolet rays. In humans, rutin (one of the names of rutoside) has a special effect on the capillary system. There is also evidence of its antimicrobial activity. And this is not all the properties that vitamin R.
The dosage form of the drug
Capillaries play an important role in the metabolism between tissue and blood. The walls of the thin vessels are composed of a single layer of endothelium. Depending on where exactly their destruction occurs, medication is prescribed by the oral or external method.
Pharmaceutical companies produce the drug in several forms. In pharmacies, you can buy rutoside in tablets, capsules - for oral administration, as well as gels, ointments - respectively, for external use. With such a variety, it is easy to choose the suitable option, and a combination of forms will increase the effectiveness of therapy.
Composition and chemical properties
The chemical instructions for the use of rutoside include its chemical name: 3 - [[6-0- (6-Deoxy-alpha-L-mannopyranosyl) beta-D-glucopyranosyl] oxy] -2- (3,4-dihydroxyphenyl) - 5,7-dihydroxy-4H-1-benzopyran-4-one.
Despite such a complex symbol, the drug is of plant origin. In pharmaceuticals, it is obtained by extraction from plants using an extractant.
The drug has a number of trade names: "Rutoside trihydrate", "Venoruton". All these medicines contain the same active substance and have an angioprotective, anti-inflammatory effect.
Vitamin P is a crystalline substance of orange or yellow color, sparingly soluble in alcohols and boiling water. The substance does not accumulate in animal tissues; it easily decomposes into simple products: carbon dioxide, aromatic hydroxy acids.
Medicinal effect
The drug rutoside has capillaroprotective properties. It is prescribed in combination with other medicines for the prevention and treatment of cardiovascular diseases.
The substance has various mechanisms of exposure:
- Slows down the course of the enzymatic reaction of hyaluronidase.
- It inhibits the process of joining natural basic compounds by active organisms.
- Natural antioxidants, getting into the blood by absorption through the intestinal walls, protect cells from damage and recreate their integrity. They help maintain the normal functioning of all systems and organs of the body.
- Rutozide is also a decongestant. The substance reduces pain, does not allow the formation of trophic ulcers. It is used for hemorrhoids. Thanks to these properties, the inflamed nodes formed are reduced, the plexuses of the blood vessels stop bleeding.
- Slows down the formation of red blood cell conglomerates and increases their ability to deform.
- Rutoside has a normalizing effect on blood pressure in hypertension.
As part of a certain complex therapy, a drug based on this substance helps to reduce peristalsis, rhythmic segmentation and other types of motor function of the gastrointestinal tract.
What diseases is prescribed a drug
Rutoside belongs to the group of low molecular weight chemical compounds. Many researchers attribute the capillary-strengthening properties of the drug to the pharmacodynamic effect, and not to the vitamin.
The drug is prescribed for P-vitamin deficiency, especially with its manifestations in the form of spontaneous intradermal hemorrhages. The use of "Rutozide" also gives effective results in other pathologies.
- Unequal increase in the lumen of the veins with the formation of protrusion in the place of its greater thinning (varicose veins).
- Vein disease, characterized by inflammation of their walls and the formation of internal blood bundles (superficial thrombophlebitis).
- Chronic venous insufficiency.
- An increase in cavernous veins with the formation of nodes in the final part of the digestive tract and in the anus (hemorrhoids)
- Severe venous pathology caused by deep vein thrombosis on the legs (post-thrombotic syndrome).
- Vascular disorders in which the retina of the eyeball is affected (retinopathy).
- Accumulation of lymph in the interstitial space and the complete cessation of its outflow, associated with an increase in the size of the affected organ. The characteristic manifestations of lymphostasis include edema, trophic skin lesions.
Rutoside in the form of a gel is used to eliminate pain and swelling as a result of fluid accumulation in the extracellular places of the body.
Contraindications
The drug has little toxicity and plant origin. But it is still a medicine and before use it is necessary to make sure that the patient can use it without consequences.
In the instructions for rutozide, the main obstacle to use is personal intolerance to the components contained in it. If the recommendations are not followed, the risk of allergic manifestations increases: edema, rash.
The use of the drug during pregnancy, especially in the first trimester, is extremely undesirable. At a later date, therapy should be carried out only as directed and under the strict supervision of a physician. In case of undesirable symptoms: pain, rashes on the skin, it is worth stopping the use immediately and seek the advice of a doctor.
How to use rutoside
Despite the fact that the drug is of natural origin, practically has no contraindications and belongs to the group of vitamins, self-medication is extremely undesirable. Moreover, the indications for use are quite severe, often chronic pathologies.
Rutoside reviews are mostly positive. But you should not focus on them, since a medication with this substance is prescribed in complex therapy and its effectiveness may decrease or increase under the influence of other drugs.
Depending on the pathology and its severity, the doctor determines the method and dosage of the use of the drug.
- Tablets are drunk regardless of the meal. The dosage is regulated by the doctor and depends on the severity of the course of the disease.
- The gel is used for external use. It is applied to the affected area with a thin layer, do not rinse off. It is convenient to do the procedure before bedtime.
Side symptoms
Rutoside is a concentrated drug substance. The high content of components contributes to the occurrence of undesirable effects.
- Indigestion.
- Various allergic rashes on the skin.
- Rush of blood.
- Headaches.
If one of the symptoms manifests itself, the use of rutoside or the drug, the active substance of which it is, should be discontinued. You should also consult a doctor and jointly decide on the advisability of using the medication for therapeutic purposes.
Analogs
Rutozide is part of many drugs related to angioprotectors. Due to its plant origin, it effectively, practically without adverse reactions, corrects the transportation of biological fluid in tissues. If for some reason it is not possible to purchase a rutoside drug, then it can be replaced with a drug that is close in the totality of properties.
- "Venorutin" is a capillary protective agent in the form of capsules. Country of manufacture Spain.
- "Rutin" refers to the group of microcirculation correctors. Reduces the permeability and fragility of capillaries, contributes to filling the deficit of nicotinic acid. It is produced by a domestic manufacturer in the form of tablets.
Troxerutin gel, Phlebopress capsule, Antistax capsule have similar pharmacological effects.
Varicose veins - a disease characterized by impaired blood circulation, which affects more than sixty percent of the population. The use of routine can increase the effectiveness of therapy and save people from interfering with an active life of the disease.