In the article, we consider the indications for the drug "Probifor", instructions for use, reviews and analogues. The drug is aimed at regulating the natural balance of intestinal microflora and is a probiotic of natural origin.
Release form
According to the instructions, "Probifor" is made in the form of gelatin hard capsules. Inside, they contain a powder of a dark gray shade with black impregnations in the form of coal, beige inclusions are possible, with a slightly expressed sour-milk smell. The drug is packaged in plastic bottles of 18, 10, 6 pieces, in plastic cans of 30, 18, 10, 6 pieces and in cardboard packs, which contain 1 bottle or can.
In addition, the dosage form of this medicament is also an oral powder having the same color as the contents of the capsules. The powder is packed in multilayer metal-polymer bags of 6, 10 or 30 sachets in one cardboard box.
Structure
The active substance of this medicinal product is live bifidobacteria (Bifidobacterium bifidum) adsorbed on activated carbon, at least 500 million colony forming units are contained in one packet of powder or in one capsule. An additional substance used in the production of both dosage forms of the drug is lactose.
Pharmacological properties
As the instruction indicates, “Probifor” is a medicine of biological origin, the action of which is aimed at stabilizing the balance of microflora in the intestine, is a probiotic.
The antidiarrheal effect of this medication is due to an increased concentration of bifidobacteria adsorbed on activated carbon elements, which are antagonists of a wide range of pathogenic (including Shigella spp., Staphylococcus aureus, Salmonella spp.) And conditionally pathogenic microbes (including Klebsiella spp., Proteus spp.).
The anti-infectious effect of this drug is enhanced by the sorption of beneficial bacteria on coal particles, which helps to accelerate the normalization of the digestive tract microbiocenosis, activate the recovery process in the mucous membranes and increase the anti-infection resistance in the body.
What else does the instruction for use with Probifor tell us? The antitoxic effect of this pharmacological product is provided by colonization of the intestines with bifidobacteria, normalization of microflora, which prevents the introduction of toxins into the internal environment and, being a natural biosorbent, accumulates in large quantities toxic substances that enter the body from the outside or are formed in it.
Bifidobacteria in high concentrations activate the processes of parietal digestion of the intestine, the synthesis of amino acids and vitamins, thereby enhancing the protective function of the intestine and immune defense in general.
Indications for use
In accordance with the instructions for "Probifor", this medication is prescribed for the following pathological conditions:
- diarrhea of various etiologies;
- dysbiosis complicating cirrhosis, diverticulosis of the intestine, viral hepatitis;
- dysbiosis of various origins, including those resulting from the use of antibacterial drugs, cytostatic, radiation or other therapy;
- foodborne toxicosis;
- intestinal infections (chronic or acute) of bacterial or viral origin (shigellosis, rotavirus infection, salmonella and enterocolitis caused by staphylococci or pathogenic microbes belonging to the genus of enterobacteria), as well as an unknown etiology;
- with intestinal absorption disorders of various etiologies;
- with symptoms of irritable bowel and other functional intestinal disorders ;
- non-specific inflammatory and chronic diseases in the gastrointestinal tract, which are accompanied by a violation of the intestinal microflora and inhibition of the reparative process of its mucous membrane (colitis, including ulcerative, gastroduodenitis, proctosigmoiditis, pancreatitis);
- pronounced degree of dysbiosis in newborns, as well as in premature babies;
- burdened premorbid background in infants, (to normalize the adaptation period).
Instructions for use with "Probifor" also indicates that with complex therapy, this medication can be used in the following cases:
- with SARS and flu;
- in severe forms of infectious, inflammatory and purulent-septic pathologies (including peritonitis and sepsis);
- with some skin diseases (for example, eczema, atopic dermatitis, streptoderma);
- with secondary immunodeficiency conditions, including in newborns;
- with oncological diseases, in the period after surgical manipulations, with chemo and radiation therapy;
- with postgastroresection disorders and conditions after cholecystectomy.
In addition, the drug "Probifor" is used in the complex treatment of surgical patients (for example, traumatological profile), to prepare for surgical procedures and prevent the occurrence of postoperative complications; in preparation for childbirth, operation "cesarean section", as well as in the postoperative period after it.
This is confirmed by the instruction to “Probifor”.
Contraindications
This probiotic is contraindicated only in cases of individual intolerance to the elements that make up its composition. An encapsulated pharmacological agent is not used in the treatment of diseases in children under five years of age (due to some difficulties in swallowing).
Dosage and administration in adults and children
The medication "Probifor" must be taken orally, while eating. The capsule is swallowed whole and washed down with boiled water or a sour-milk drink. The powder of this drug immediately before administration should be mixed with liquid food (in this case, it is optimal to use fermented milk products or dissolve in boiled water at an average temperature). For infants, the drug is mixed with breast milk or an artificial formula for feeding. When mixed in water, a cloudy suspension is formed with sorbent particles, and it is necessary to drink it immediately, without waiting for the powder to completely dissolve.
Instructions for use with "Probifor" for children and adults reports that the recommended dosages for toxic foodborne infections, diarrhea syndrome and acute infectious intestinal diseases are:
- Adults and children after 7 years - two capsules or packages twice a day. The therapeutic course is 2-5 days.
- To quickly eliminate the symptoms of diarrhea, adults can use 3 capsules or packets twice a day at intervals of one hour, or 6 capsules or packets once a day. This treatment technique should last from one to three days.
- Children 5-7 years of age are prescribed one capsule or packet three times a day, with short intervals of a couple of hours. The duration of treatment is 2-3 days. If the clinical symptoms persist, it is possible to extend the therapeutic course to 4-5 days.
- Children after 6 months are given 1 sachet three times a day. In case of urgent need, you can give the child this drug at small intervals of 2-3 hours. The duration of such treatment should be at least 3 days, however, if pathological symptoms persist, the duration of therapy increases by another two days.
- According to the instructions to “Probifor”, experts recommend that children under six months of age give 1 sachet 2 times a day for three days, and if necessary, 4 days.
Recommended dosages for pathologies of the digestive tract of the chronic course and functional intestinal disorders:
- Adults are prescribed three capsules or sachets of the drug once a day during dinner.
- Children after 5 years - 3 capsules or sachet once a day.
- Children under 4 years - 3 sachets once at dinner. The duration of the therapeutic course is 5-14 days.
In severe stages of the disease, dosages are increased: up to six capsules or packets per day, for babies from one year to five years - up to 4 packets per day. The course of therapy can be up to one month.
This is stated in the instructions for use. Analogs of "Probifora" should be selected by a doctor.
Recommended dosages for dysbiosis, intestinal infections of a chronic nature, skin pathologies, immunodeficiency conditions, as well as to normalize the period of adaptation in infants:
- adults and children after 7 years - 3 capsules (packet) 2 times a day;
- children 5-8 years old - one capsule (packet) three times;
- children 3-6 years old - 1 sachet 3 times a day;
- babies under 3 years old and newborn babies - 1 packet twice a day;
- premature babies - 1 sachet once a day.
The duration of such a treatment course in this case is up to ten days.
Adverse reactions
In accordance with the instructions and reviews to "Probifor", if you take this pharmacological agent in the recommended dosages, it usually does not cause side effects and is well tolerated by patients of all ages. With an increase in dose, they may experience symptoms of dyspeptic disorder, stool disorder. It is worth noting that the instructions for the Probifor powder and capsules describe this in great detail.
Special recommendations
As an additional component, this medication contains lactose, therefore, patients with lactase deficiency are used with extreme caution. Probiotic is approved for use during pregnancy and lactation.
Drug interaction
With the simultaneous use of the medication in question with antibacterial agents for oral use, its effectiveness is significantly reduced. Vitamin complexes, on the contrary, enhance the effects of the probiotic "Probifor". Instructions for use with powder and capsules confirm this.
Analogs
The analogues of this drug are:
- "Probiotics";
- "Beefinorm";
- "Bifidumbacterin";
- Lactofiltrum;
- "Beefiform";
- "Liobifidum";
- Lifepack;
- BifoVir.
Reviews about the drug
A lot of positive reviews were left about this drug, especially for parents whose children it was prescribed for the treatment of various intestinal pathologies. They observed a positive effect of therapy in the early days, normalization of stool, general well-being was observed in the babies, the level of anxiety and tearfulness of children decreased due to the cessation of abdominal pain. In addition, the great advantage of this medication, according to parents, is that you can use this medicine even in newborns and premature babies, which plays a special role in maintaining the health of this group of patients.
Adults who took the drug "Probifor" were also satisfied and observed the high effectiveness of the drug in the treatment of dysbiosis caused by taking antibacterial oral drugs, as well as various pathologies of the digestive organs of a chronic nature. They note the normalization of stool, the disappearance of symptoms of heaviness in the stomach, flatulence, heartburn and many other pathological phenomena.
Reviews of specialists
Reviews of doctors say that this tool is one of the most modern in the domestic pharmacological market, however, it is very effective. It is prescribed to patients of absolutely all ages, not only for the treatment of certain diseases, but also for prevention in various situations of high probability of their development. For example, when treating with antibiotics, bifidobacteria should be prescribed, which helps to avoid the development of diarrhea, which is a consequence of the effects of such medicines on the intestines. The occurrence of candidiasis of the mucous membranes is also excluded.
We reviewed the indications for the "Probifor", instructions for use and reviews.