An effective antiviral treatment and prophylactic agent that allows you to fight herpes virus infection, herpes zoster, nonspecific colpitis and vaginosis, and papillomavirus infection is Epigen. Reviews of patients indicate that the medication helps to get rid of discomfort in the genital area, is used to treat cervical erosion.
Composition and form of release
A medicine is produced in the form of a spray (gel), intended for local and external use. The product is contained in bottles equipped with a nozzle for vaginal use. The active substance is glycyrrhizic acid. Auxiliary components include propylene glycol, tween-80, folic, ascorbic, fumaric, maleic acids.
Pharmacological properties
Due to the presence of glycyrrhizic acid, which is isolated from licorice root, the Epigen preparation (reviews say this) has immunomodulatory, antipruritic, regenerative, anti-inflammatory, and antiviral properties.
The drug has a detrimental effect on the RNA and DNA of many viruses (varicella, herpes simplex, various papilloma viruses, cytomegalovirus). The antiviral effect of the drug is associated with the indication of interferon. The drug causes the replication of viruses in the early stages. This occurs as a result of a selective dose-dependent slowdown of phosphorylating kinase P.
The drug, interacting with viral structures, changes the phases of their cycle, as a result of irreversible inactivation of viral particles in a free state. The tool blocks the penetration of viral proteins into the cell, disrupting the ability of microorganisms to synthesize new viral particles. The medication has immunomodulatory and anti-inflammatory properties. It slows down the activity and formation of phospholipase and prostaglandins in peritoneal activated macrophages, accelerates the movement of leukocytes in the affected area, and activates oxygen-dependent mechanisms of phagocytosis.
The drug has a membrane-protective effect, reduces the intensity of lipid oxidation, linking toxic oxidation products and free radicals. Regenerating properties are associated with improved recovery of mucous membranes and skin.
The drug "Epigen" is an intimate spray (reviews confirm this fact), it is very convenient to use, and its effect begins from the first seconds after irrigation. When used externally, the active substance accumulates in the affected areas. Due to the slowly occurring absorption, glycyrrhizic acid practically does not enter the systemic circulation.
Indications for use
The medication is prescribed for the treatment of herpes virus infection (primary acute and recurrent), which causes the herpes simplex virus type 1 and 2. The Epigen gel gel effectively copes (doctors' reviews indicate this) as part of a complex treatment with herpes zoster, excited by the Varicella Zoster virus .
The drug is used for the treatment of papillomavirus infection, the treatment and prevention of pathology of the cervix and genital warts, the prevention of relapse of infections caused by cytomegalovirus, papilloma, herpes.
The medication is used to treat and prevent conditions that are accompanied by a decrease in local immunity. As part of combined and complex treatment, the drug is prescribed for vaginal dysbiosis, bacterial vaginosis, vulvovaginal candidiasis, nonspecific colpitis.
Used "Epigen" spray for erosion. Patient reviews say that the tool effectively eliminates discomfort. The medicine restores tissue, suppresses pathogenic microbes, prevents the formation of a malignant process.
Epigen is an intimate gel (patient reviews provide information on this), which helps to cope with discomfort in the genital area, accompanied by dryness, burning, itching, as well as in hypoestrogenic conditions. The drug is used as a preventive measure during sexual intercourse (to prevent sexually transmitted viral infections).
Mode of application
Before use, the medicine bottle must be shaken, during the procedure it should be kept upright. Thus, the Epigen drug from thrush is used. Patient reviews say that it must be applied to the entire affected surface, keeping the can at a distance of 5 cm. The optimal therapeutic dose is considered to be 2 pressure on the valve.
Intravaginal administration of the drug is carried out through the supplied vaginal nozzle. It is presented in the form of a hollow tube 7 cm long, at the opposite ends of which there is a valve and a spray. Before use, the atomizer valve is removed from the balloon and the nozzle is put on, which is introduced into the body, producing 1-2 injections. This allows you to evenly apply the medicine to the internal genital organs. After the procedure, you should stay in a lying position for 10 minutes, it is recommended to wash the nozzle with soap in warm water for hygienic purposes.
“Epigen intimate” (reviews of the male part indicate this), except for external use, they are injected 2 times per procedure into the opening of the urethra using an atomizer, which is kept at a distance of 1 cm from the organ. According to a similar scheme, a medicine is used for the clinical extragenital manifestations of herpes.
Treatment regimens
With cytomegalovirus infection and genital herpes, the drug is used for two weeks 5 times a day. The spray is applied both externally and intravaginally. After relapse localization, the drug is used three times a day for 10 days. To prevent relapse of these diseases, the medication should be used in the morning and evening from the 20th day of menstruation until their end.
With shingles, it is required to apply the Epigen preparation 6 times a day. Patient reviews say that after using the medicine, the amount of rash decreased significantly, and they used the spray until all the signs of the disease disappeared completely.
When papillomas are located in the perianal region, near and directly on the genitals themselves, the medication is prescribed 6 times a day. Procedures are performed within a week. To prevent the progression of papillomavirus infection, you should use the spray before and after sexual intercourse, as well as 3 times a day with the appearance of provoking factors: overwork, stress, taking cytostatics, antibiotics, microflora disorders, respiratory viral infections.
For the treatment of vaginosis, nonspecific colpitis, the Epigen-gel remedy (reviews of doctors and their prescribing evidence of this) should be used vaginally for a week. If no improvement has occurred, the treatment is repeated after 10 days.
With manifestations of discomfort in the genital area, characterized by dryness, burning and itching, as well as as a result of insufficient functioning of the ovaries, the drug is prescribed 2 times a day for three weeks.
Contraindications
It is not recommended to use the drug for individual intolerance to glycyrrhizic acid and other components. With caution, you should use the drug "Epigen" during pregnancy. Patient reviews say that the medicine helps well with manifestations of thrush, helps protect against infection before childbirth. You can use the medicine during the entire period of pregnancy and lactation according to absolute indications. Studies have not established teratogenic and embryotoxic effects of the drug.
Side effect of Epigen
Reviews of patients indicate good tolerability of the drug. In rare cases, allergic manifestations (including contact dermatitis) can be observed.
special instructions
For the effective action of the drug, wash the affected areas should not be. If there are signs of irritation, intolerance, you must stop using the Epigen medication (intimate gel). Reviews say that in rare cases, suppuration can form in the affected areas, as well as an unpleasant odor. In such situations, you need to contact a specialist.
Drug interaction
The drug can be used when taking the main groups of medicines (painkillers, anti-inflammatory, antiseptics, antibiotics), which are used for additional therapy of the above diseases. With the simultaneous administration of antiviral drugs (interferon alfa, iodouridine, acyclovir), their effect is enhanced. During therapy of a viral infection with the help of the Epigen preparation, it is not recommended to take interferonogens (tilorone, kridanimod).
The medicine "Epigen" (intimate spray): reviews
Patients leave conflicting reviews about the drug. In some cases, no improvement was observed after its use; in others, patients praise the spray. Especially a lot of reviews about the favorable disposal of thrush with medication. People say that after several procedures they went through burning and itching. Many talk about plans for using the drug as a preventive measure, which is especially true in the spring, when immunity is weakened.
Some patients say they used the medicine during pregnancy. Moreover, the doctors advised them to spray, since it contains licorice and lactic acid, there are no dyes and perfumes. Women say that they used the medicine throughout their pregnancy and continue to do so at present. Thanks to the drug, they forgot about irritation and dryness in the intimate zone.
Analogs and price
The structural analogue of the Epigen medication is glycyrrhizic acid. According to the pharmacological effect, the preparations “Vagical”, “Vagilak”, “Lactormorm” possess similar properties. The same active ingredient - licorice root extract - is also found in the medicines "Glyciram" and "Epigen labial", however, the indications for these medicines are different. Women leave feedback that glue mousse, Nivea gel, Lactacid gel can be used as a hygiene product. The cost of the Epigen spray is about 700 rubles.