Fungal lesions of the skin and mucous membranes cause a lot of inconvenience to their "owners". The antimycotic drug Pimafucin is often prescribed by doctors of various specialties in clinical practice for the treatment of mycoses caused by fungi of the genus Candida. Let's look at Pimafucin, cheaper analogues that are also successfully used in venereal skin practice.
Pharmacological characteristics of the drug
The main active substance "Pimafucin" (regardless of the form of release) is represented by natamycin. This is an antibacterial drug from the group of polyenes, has a wide antifungal effect.
Natamycin has one distinctive feature - in relation to it, almost no cases of allergic diseases have been identified, and there has been no decrease in the effectiveness of the drug with prolonged or repeated use.
The effect of various forms of the drug
One of the forms of release of the drug “Pimafucin” is tablets (the analogue is cheaper represented by the tablet forms of the preparations “Griseofulvin”, “Fluconazole”). Such agents are effective in the intestines. This is due to the fact that the tablets are equipped with a special enteric-soluble membrane, which promotes the release of the drug only in the intestinal lumen.
Candles "Pimafucin" (a cheap analogue - "Natamycin"), used to treat vaginal infections with yeast fungi, also show an effective effect. After administration, the vaginal suppositories melt quite quickly with the formation of a foamy mass containing the active substance of the drug. This mass effectively envelops the vaginal mucosa, especially its upper parts, contributing to a speedy recovery.
Pharmacokinetics of the drug "Pimafucin"
Regardless of the form of the drug used or its analogues, using modern research methods it was not possible to identify the content of the active substance in the blood or biological fluids.
Thus, Pimafucin, cheaper analogues containing natamycin, are active provided they are used externally or locally and do not have a resorptive effect.
Indications for use
Each dosage form has individual indications for use. Pimafucin tablets are used in the treatment of fungal infections of the intestine caused by forms sensitive to it. Vaginal suppositories are prescribed for the treatment of various vaginitis caused by fungi, and a cream with natamycin - for the treatment of skin mycoses.
A distinctive feature of the drug is the lack of its effect on the fetus, so Pimafucin (suppositories), cheaper analogues can be successfully used in pregnancy.
Methods of using the drug and optimal dosage
In the treatment of fungal diseases of the intestine, a tablet form of the drug substance is used (usually 1 tab. * 4 r / d). In this case, therapy lasts no more than 1 week.
In the treatment of fungal diseases of the intestine in children from three years of age, the dosage remains the same as in adults, but the frequency of doses is reduced to two times a day. Due to the pharmacokinetics of natamycin, the dose and frequency of administration remain unchanged for children of all ages.
In the treatment of fungal lesions of the vagina, it is recommended to introduce 1 vaginal suppository at night, in the supine position. It is necessary to carefully and as deeply as possible enter the drug. The course of therapy: from three to six days. Treatment of the disease must be completed before the start of the menstrual cycle or started immediately after its completion.
In the case of the treatment of fungal diseases of the skin, the preparation in the form of a cream is applied to the affected areas from one to four times a day. The duration of treatment in this case is about 3 weeks.
It is worth remembering that if the attending physician prescribed Pimafucin (suppositories), analogues can also be purchased cheaper in online pharmacies, of course, after consulting a specialist. You can also consult with a pharmacist in a pharmacy, although his recommendations should be treated with caution.
Contraindications
Due to the peculiarities of pharmacodynamics, the drug in any form is practically devoid of contraindications. The only contraindication in which you should abandon the use of the drug is hypersensitivity to one or more components of the drug.
Side effects
When using the tablet form of the drug, the appearance of disorders of the gastrointestinal tract, which are manifested by the relaxation of stools and nausea, is possible. These symptoms, as a rule, are associated with the start of the drug, go away on their own and do not require additional therapy.
When using the drug in the form of a cream, itching and burning may occur in the area of application to the skin. If these symptoms remain after two or three times the application of the drug, its use should be discarded, since the symptoms are probably due to an allergic reaction to the components of the drug.
"Pimafucin": cheaper analogues
Given the fact that the active substance of Pimafucin is natamycin, a fairly large number of analogues of this drug can be found on the pharmaceutical market. It must be remembered that any analogue of Pimafucin is cheaper than the original. This is due both to the dosage form itself and to the components that make up the drug, the cost of conducting clinical trials in order to prove effectiveness.
Replacing the candles "Pimafucin", a cheap analogue can be chosen in the form of the drug "Primafungin". Also, an inexpensive analogue of this drug will be Ecofucin. Among the similar analogues of this drug, which have a component that is different from natamycin, which has an antifungal effect, we can note Griseofulvin (as cheap candle catalogs Pimafucin) and a drug like Nystatin Ointment.
Conclusion
The drug "Pimafucin", cheaper analogues containing natamycin, are effective medications for the treatment of mycoses, fungal mucous membranes, as well as the digestive system. Natamycin is practically safe to use, and therefore can be recommended for use by both adults and children. Choosing an analogue of Pimafucin cheaper, you need to pay attention to the safety of the components of the drug, especially its use during pregnancy. In any case, if you are using the original drug or generic, be sure to consult a specialist before you buy it. After all, only a doctor can prescribe medications and control their intake in order to avoid the occurrence of undesirable effects.