The drug "Joset", the instructions for the use of which we will consider below, is a syrup with a mucolytic, expectorant and bronchodilator effect. The combined composition of the drug includes bromhexine, menthol, salbutamol, guafenesin. The complex effect improves the motility of the bronchial membrane, synthesizing mucus with a liquefied consistency. As a result, sputum discharge is activated, breathing is facilitated.
Composition and form of release
The instructions to the "Joset" indicated that the syrup in its composition has several active substances that determine the main therapeutic effect of the drug. Among them:
- Bromhexine in the form of hydrochloride (2 mg per 5 ml of the drug).
- Guaifenesin (50 mg per 5 ml).
- Salbutamol sulfate (1 mg per 5 ml).
- Levomenthol (0.5 mg per 5 milliliters of syrup).
Among the additional components of the preparation under consideration, purified water, sodium para-hydroxybenzoate, propylene glycol, glycerin, sorbitan acid, sucrose, yellow dye, sodium saccharin, sorbitol are noted. These elements form the density of the drug, its aroma and taste.
Pharmacology
Due to the combined composition of this drug has a complex effect on the body. In the instructions to "Josette" you can learn in detail about each active substance and its features:
- Salbutamol affects the expansion of the bronchi, as a result of which sputum discharge is activated, the formation of spasms in the upper respiratory tract is prevented.
- Guaifenesin promotes liquefaction of sputum by reproducing a dry, persistent cough into a moist and easily expectorant one.
- Bromhexine actively exhibits the effect of mucolytic, while sputum loses viscosity and density. The main purpose of the component is the activation of expectoration due to irritation of the cilia of the ciliated epithelium. Bromhexine also accelerates the elimination of dry cough.
- Menthol relieves bronchospasm, stimulates the secretion of the glands of the respiratory system, soothes the irritated mucous membrane, acting on it as an antiseptic.
To whom is syrup indicated?
The instructions for use indicate that the drug is indicated in the following cases:
- Patients with impaired lung tissue contraction.
- With inflammation of the mucous membrane of the bronchi.
- In the case of pneumonia, bronchitis, bronchial asthma.
- In case of respiratory diseases as a result of ingress of technical dust into them.
- With pulmonary tuberculosis and chronic lung dysfunctions caused by external factors (poor ecology, smoking and the like).
The syrup in question refers to potent drugs, before taking it, it is recommended to consult a doctor, especially if treatment of the child is expected.
Contraindications
The instructions for the syrup "Joset" indicated a number of contraindications. Among them:
- Impaired thyroid function.
- Diabetes.
- Heart rhythm malfunction.
- Increased intraocular pressure.
- Myocarditis.
- Stenosis of the aortic valves.
- Serious damage to the kidneys and liver.
- Pregnancy and lactation.
- Bleeding in the digestive tract, the presence of disseminated blood in the feces of unknown origin.
- Exacerbation of a stomach ulcer and duodenal ulcer.
With caution, syrup is prescribed for people with arterial hypertension against the background of the use of beta-blockers.
Pregnancy and breastfeeding
The instructions to "Joset" noted that during pregnancy and lactation, the drug in question should not be taken. This is due to the fact that it is not known what effect salbutamol, which is part of the drug, has on pregnancy and the development of the fetus. Some components of the syrup can pass into breast milk and the baby’s body.
Side effects
The drug in question, along with high efficiency in rare cases, can cause side effects. They appear as follows:
- From the cardiovascular system - lowering blood pressure, tachycardia.
- Problems in the digestive tract - diarrhea, constipation, exacerbation of peptic ulcer, gastritis, duodenitis. Sometimes abdominal pain, nausea and vomiting occur.
- In the urinary system, guaifenzin helps stain urine pink.
- From the side of the central nervous system - excessive excited state, anxiety, dizziness, migraine, drowsiness or insomnia, tremor, convulsions.
- Allergic reactions - skin rash, dermatitis, itching, urticaria.
In case of overdose
An excessive dose of syrup (if the child accidentally drank a large amount of the drug) leads to vomiting, drowsiness (sometimes, on the contrary, to excitability), tachycardia. Headache, collapse, diarrhea, and a number of other negative symptoms may occur. It is immediately necessary to see a doctor, treatment is symptomatic.
Syrup "Joset": instructions for use
User reviews indicate the high effectiveness of this drug. The main thing is to observe the correct schedule for taking and the proportions of the drug. The recommended dosage schedule (unless otherwise prescribed by the doctor) is indicated below:
- The syrup is taken orally by children under six years old, one teaspoon (5 ml) three times a day.
- Patients aged 6-12 years are recommended to use the drug for 1-2 tsp. three times a day.
- Patients over 12 years of age are prescribed two teaspoons (10 ml), three doses per day.
Features
Users should pay attention to several recommendations specified in the instructions for the use of "Joset" for children, namely:
- Remember that one of the components of the syrup (guaifenesin) contributes to the appearance of pink blotches in the urine.
- It is undesirable to drink the indicated medicine with a drink with a high alkali content.
- With great care, "Joset" should be used for people with diabetes mellitus, arterial hypertension, a stomach ulcer and duodenal ulcer. Especially if MAO inhibitors (the enzyme monoamine oxidase) or beta-adrenergic blockers are used at the same time.
Syrup is dispensed in pharmacy chains only by prescription. Shelf life is 24 months at a temperature not exceeding 26 degrees Celsius in a dark, dry place. After opening the bottle - no more than six months. At the end of the shelf life, it is forbidden to use the medicine. The average packaging price per 100 milliliters is 180-200 rubles.
Interaction with other medicines
In this aspect, it is noted that GCS (glucocosticosteroids) and diuretics enhance the main effect of salbutamol. Tricyclic antidepressants and MAO inhibitors also significantly increase the effect of sulbatumol, which is fraught with a sharp decrease in blood pressure. There is a likelihood of developing tachycardia and arrhythmias with the simultaneous use of "Joset" with theophylline, beta-2-adrenergic agonists and other xanthines.
Antibiotics penetrate the lung tissue when taken together with bromhexine. It is not recommended to combine the use of syrup and non-selective beta-adrenergic receptors. The discharge and liquefaction of sputum is complicated by drugs containing codeine.
Analogs
When choosing Josette syrup for children, the instructions must be carefully studied. The same applies to drug substitutes. These include the following medicines:
- "Salbutamol" in liquid form.
- ACC.
- Libexin.
- "Bromhexine."
- "Kashnol."
- "Herbion".
- "Bronchosan."
Many of the analogues are cheaper, but include only one or two active components.
Reviews
The instructions to the "Dzhet" indicate the indications and contraindications, composition, recommendations and other nuances. However, it is better not to engage in self-medication without first consulting a doctor. Users note the high effectiveness of the drug. Reviews are mostly positive, side effects are extremely rare, but the cough is pretty fast. Also, consumers indicate the affordable price of the medicine, which for many families is very important.
Another important plus of the syrup is the possibility of its use for both adults and children of almost any age. For pregnant women and nursing mothers, the drug is not recommended, like many other medicines. If you decide to be treated with "Joset" during lactation, take a break in breastfeeding during therapy.
Total
The drug in question is available as a syrup for internal use. It is packaged in dark glass bottles of 100 or 200 milliliters. The kit includes detailed instructions and a measuring cup. Thanks to a combination of several active ingredients, the drug comprehensively affects the affected areas, providing effective treatment for any type of cough.