In the article, we consider the instructions and analogues for the Neo-Penotran candles.
A medication in the form of suppositories is a combined drug that has a pronounced antimicrobial, antiprotozoal and antifungal effect. The drug is used in the field of gynecology for the treatment of various pathological processes of infectious genesis that occur in the urogenital tract of a woman, provoked by various harmful microorganisms that are sensitive to the components of suppositories.
Structure
According to the instructions for Neo-Penotran, these are white, flat, with a rounded end of the candle. The medication is a combined drug, which means the presence in the composition of two active components at once:
1. Metronidazole in micronized form.
2. Miconazole nitrate in micronized form.
As an auxiliary component of candles, vitepsol acts. Suppositories are packaged in packages of 7 pieces. In addition to suppositories, the package contains instructions for use and fingertips.
The properties
As the instruction for Neo-Penotran suppositories indicates, the substances included in its composition have the following pharmacological properties:
1. Metronidazole has an antiprotozoal and antibacterial effect, showing activity against most harmful bacteria, especially the anaerobic type, as well as protozoa, unicellular, such as gardnella and trichomonads.
2. Miconazole is an antifungal agent that shows a high degree of activity against various fungi, including candida that causes thrush.
Pharmacokinetics
After administration of the suppository intravaginally, metronidazole partially enters the systemic circulation, while miconazole has the property of accumulating in one place. Metronidazole is further metabolized in the liver to the state of inactive decay products and excreted in the urine.
Indications for use
In accordance with the instructions for Neo-Penotran, suppositories are used for pathologies of structures of the urogenital tract of infectious origin, which occur against the background of infection with microorganisms that are sensitive to the components of the drug. Neo-Penotran is used in the following cases:
1. Vaginal candidiasis. The disease is an inflammatory process caused by an active state of fungal infection, provoked by the multiplication of a microorganism called candida.
2. Vaginosis. It is a violation of the microflora in the mucous membrane when opportunistic and pathogenic bacteria begin to prevail.
3. Trichomonas vaginitis. The inflammatory process in the vaginal mucosa, which is caused by unicellular protozoan microorganisms Trichomonas.
In addition, suppositories are prescribed for the treatment of vaginitis provoked by mixed microflora (fungi, pathogenic bacteria and protozoa).
Restrictions for use
According to the instructions, Neo-Penotran is not recommended for use in certain physiological and pathological conditions. So, the drug is contraindicated in the following cases:
- Hypersensitivity of the body to the components that make up the drug.
- The patient's age is under 18 years old, as well as in the case of preservation of the hymen at a later age. This is due to the lack of evidence of the safety of the drug in the described situations.
- Porphyria. They are impaired pigmentation. The disease is caused by a genetic factor, is associated with an increased level of porphyrins in the body.
- Epilepsy. It is a pathology of the structures of the nervous system of a functional or organic type. The disease is characterized by convulsive attacks of the tonic-clonic type, as well as impaired consciousness.
- Liver insufficiency of a functional nature, which appeared as a result of pathological processes of various nature.
- Bearing a child in the last trimester.
Before starting treatment with Neo-Penotran, it is necessary to study the instructions, paying particular attention to the item with contraindications. This will help to avoid the negative consequences of using the drug.
Instructions for the use of candles "Neo-Penotran"
Suppositories are administered intravaginally. For this, special sterile fingertips are included. The suppository is taken from the blister and inserted deep into the vagina.
The standard dosage regimen is the introduction of one suppository at bedtime for one week. If we are talking about a serious course of an infectious disease or an inflammatory process of a chronic course that is provoked by a stable microflora, the course of treatment with Neo-Penotran suppositories according to the instructions is extended to two weeks. If the drug is prescribed for women over 65, the dosage does not change, it also amounts to one suppository per day.
Overdose
To date, there have been no cases of overdose of suppositories for intravaginal administration of Neo-Penotran. If the candle was accidentally swallowed, it is necessary to wash the stomach and take sorbents. There is no specific antidote, therefore, if an abnormal amount of metronidazole is absorbed into the bloodstream, symptomatic treatment is performed.
Side effects
Neo-Penotran is able to provoke the appearance of a number of undesirable reactions. So, against the background of treatment with vaginal suppositories, the following symptoms may appear:
- Local reactions, manifested by burning and itching in the vagina after administration of a suppository. As a rule, a similar symptom appears at the initial stage of administration and disappears after several days of using the drug. Specific treatment in this case is not required.
- Negative consequences of a systemic nature. A number of adverse reactions occur as a result of the absorption of a certain amount of metronidazole into the systemic circulation. As a result, mental changes, such as anxiety or mood lability, convulsive syndrome, ataxia, which is impaired gait, leukopenia, loss of appetite, nausea and vomiting, soreness in the epigastric region, diarrhea, dry mouth, high fatigue, and a taste of metal in the metal to the mouth.
The occurrence of local adverse reactions does not require discontinuation of the drug and is the norm. However, in case of detection of systemic adverse reactions, stop using candles and consult a doctor.
What else can you learn from the instructions for use with Neo-Penotran?
Special recommendations
Before you start using the product, you must carefully read the instructions, paying attention to special instructions. These include the following:
- You can not combine the use of suppositories with alcohol. Refuse alcohol will need a few days before and after the course of treatment.
- During the use of Neo-Penotran in gynecology, according to the instructions, special care must be taken when using barrier methods of contraception, since the suppository capsule can damage the condom.
- In the treatment of Trichomonas vaginitis, it is necessary to conduct sexual partner therapy.
- During the use of suppositories, unprotected sexual intercourse should be avoided.
- Metronidazole is able to enter into drug interaction with other drugs. For this reason, you should inform the specialist about all medicines that are taken at the time of the appointment of Neo-Penotran.
- The drug does not affect the speed of psychomotor reactions, therefore, against the background of its use, you can drive a car and perform high-precision work that requires an increased concentration of attention.
Suppositories are dispensed in pharmacies without a prescription from a doctor. However, this does not mean that Neo-Penotran can be used on its own.
Analogs
In the instruction to "Neo-Penotran" analogues are not presented.
There are a number of drugs that have a similar effect and composition. Let's consider some of them:
1. "Klion-D 100". Replace Neo-Penotran with a similar composition. The drug is based on metronidazole and miconazole. It is also available in the form of suppositories for intravaginal administration. "Klion-D 100" is prescribed for the treatment of candidiasis of the vulva and vagina, mixed and non-specific varieties of vaginitis. Indications and possible adverse reactions are similar to the original drug. It can be itching and burning in the vagina, allergic reactions, etc.
2. “Trichopol”. It is produced in the form of tablets and is prescribed for the treatment of many types of infectious diseases. The drug is based on metronidazole, which has an effect on pathogenic microflora. In addition to getting rid of Trichomonas vaginitis, Trichopolum is used to eliminate pathologies of the intestinal tract of an infectious nature, pneumonia, joint infections and endometritis. The treatment regimen and its duration is set depending on the diagnosis. The drug is contraindicated for leukopenia, individual intolerance and epilepsy. Adverse reactions while taking the drug are manifested in the form of pain in the head and stomach.
3. "Metromicon-Neo." It is a drug with antifungal and antibacterial effects. It is produced in the form of vaginal suppositories. Candles are prescribed to treat vaginal infections. The main difference from Neo-Penatran is the lowered dosage of the active ingredients. The duration of therapy, as well as the dosage regimen, depends on the diagnosis. "Metromicon-Neo" can not be used in the first trimester of pregnancy, during lactation, for girls under 18 years of age and girls who have not started sex life.
4. “Vagiferon” (candles) - an analogue of “Neo-Penotran”. The instructions for use say that these suppositories are intended for the treatment of infectious diseases of the vagina. The main difference from the original is the composition of the preparations. The amount of metronidazole in Wagiferon is reduced, but fluconazole and human interferon are added. Suppositories are active against trichomonads, gardnellas, microplasma, herpes viruses, vaginosis and vaginitis of bacterial origin.
5. Livarol. Also available as suppositories. Ketoconazole acts as the active component in this drug. The drug has an antifungal effect, destroying such infectious pathogens as streptococci and staphylococci. In the composition of "Livarol" there is no metronidazole. It is also prescribed for the restoration of the vaginal microflora after taking antibacterial drugs.
Also on sale, you can also find "Neo-Penotran Forte."
Instructions for use with analogues of the product will not be discussed in detail.
conclusions
Thus, if a medication is not suitable for any reason, it can be replaced by other, equally effective drugs, including based on other active components. However, any change in the treatment regimen requires specialist advice.