Most often, Burkitt's lymphoma is diagnosed in people living in Oceania and Africa. Only recently have single cases of such a disease been reported in the United States and Europe. Fortunately, in the early stages, the disease is most often treatable.
Causes of Lymphoma
Burkitt's lymphoma is a malignant tumor, prone to rapid aggressive growth. The appearance of such a neoplasm is the result of malignant degeneration of B-lymphocytes.
Until recently, Burkitt's lymphoma was associated with exposure to radiation and dangerous carcinogens. However, recent studies have shown that malignant degeneration in this case is associated with viral activity. In most patients with such a tumor, the Epstein-Barr virus was detected in the body. It is believed that after binding of the viral particle to the lymphocyte, its uncontrolled division is possible - this is how the tumor forms.
Most often, Burkitt's lymphoma is diagnosed in children aged three to seven years. However, the development of the disease is not excluded in more adulthood.
Burkitt's Lymphoma: Symptoms
According to statistics, in about 30% of cases, the tumor affects the intestines. Often lymphoma is formed in the area of the kidneys, ovaries, testicles, stomach, pancreas, adrenal glands, and jaw. Much less often with an ailment, the
salivary glands and thyroid
gland suffer.
Malignant degeneration of cells begins in the lymph node. At this stage, the symptoms of lymphoma resemble a cold. Patients complain of chills, fever, swollen lymph nodes. Only after this begins the rapid growth of the neoplasm.
The symptoms accompanying Burkitt's lymphoma depend on its location. For example, a tumor formed near the salivary glands during growth leads to deformation of the bones of the face and displacement of the nasal septum. A neoplasm in the intestine can provoke the development of intestinal obstruction. If the kidneys are affected, then the gradual development of renal failure is not excluded.
In any case, a rapidly growing tumor affects nearby organs, disrupts their normal functioning, and also constricts the vessels and nerve endings.
How is Burkitt's lymphoma treated?
As a rule, a biopsy with further
histological examination of tissues is necessary to make an accurate diagnosis. As for therapy, it depends on the severity of the disease, the size of the tumor and its growth rate.
In the initial stages, patients undergo chemotherapy. Since the disease is most often associated with a viral infection, they resort to immunomodulating and antiviral therapy - patients are prescribed interferon in large doses. It has been proven that taking such a drug accelerates the healing process and enhances the effect of chemotherapy.
If the tumor is too large and poses a threat to the patient's life (for example, lymphoma in the salivary glands often passes to the tissues of the pharynx and trachea), then a surgical operation is necessary to remove it. After this, chemotherapy and antiviral treatment are prescribed, which help to destroy the remaining malignant cells and prevent the development of relapses.