Acne, or acne, is an inflammatory skin disease that often appears in adolescence and usually disappears by the age of thirty. The disease, as a rule, does not cause serious consequences, but causes a person severe psychological discomfort: purulent and inflamed acne look unattractive.
Reviews about "Klindovit" are abundant.
Composition and dosage forms
As an active substance, clindamycin has various forms of release - drugs for intramuscular injection, oral administration and external in the form of an ointment. “Klindovit” has only one form of release, namely gel. The preparation is colorless, almost transparent, has a specific aroma. It is produced in aluminum tubes in an amount of 30 grams and in cardboard packaging.
The main active ingredient in Klindovit is clindomycin phosphate, in terms of one gram of clindamycin per ten grams of ointment.
Excipients are as follows: allantoin, castor oil, propylene glycol, carbomer interpolymer, nipagin, carbomer copolymer, macrogol 400, as well as purified water.
Drug features
Acne is usually fought with topical medications. A typical picture of the pathology is as follows: excessive secretion of sebum, which for one reason or another has lost its antibacterial properties. Fat, accumulated, is blocked in the ducts of the glands and follicles of the skin. In this case, a gram-positive anaerobic bacterium is activated and then multiplied.
The immunity system eliminates the pathogenic microflora, the pus that forms during this process is “packed” into special capsules, that is, into abscesses. You cannot get rid of them mechanically: a small amount of pus in the duct causes a new stage of bacterial reproduction.
Gel “Klindovit” is an antibiotic from the number of linkosamides, which has a narrow spectrum of influence, but it destroys directly the pathogen of the bacterium - gram-positive cocci. Thus, the medicine, once on the skin, inhibits bacterial activity and reduces the secretion of sebum, while affecting both the environment and the pathogen.
The active component of the drug is clindamycin, that is, a lincomycin derivative in the form of a phosphoric acid salt. The active substance inhibits protein synthesis in gram-positive cocci, that is, it has both bactericidal and bacteriostatic effects (inhibits reproduction). Clindamycin, in comparison with lincomycin, has improved pharmacological characteristics, so the initial antibiotic was displaced.
“Klindovit” is effective in all kinds of acne: acne, internal acne, including large, purulent acne, because the substance acts on the pathogen Propionibacterium acnes (all strains).
The drug can be purchased without a prescription, but you need to consider that it has a narrowly targeted effect, so that with a different type of pathogen, the ointment will be ineffective.
Dosage and application features
Acne mainly affects the skin of the face, forearm, back, chest, that is, those areas where a large number of sebaceous glands are located. “Klindovit” is applied precisely to these areas. A standard treatment course takes from six to eight weeks, but at the insistence of a specialist, it can be extended up to six months. There were no cases of addiction.
Klindovit gel is applied in a very thin layer two to three times a day. The skin must first be cleaned and dried. Care must be taken that the product does not get into the oral cavity or eyes.
Klindovit tablets are used in the complex treatment of inflammatory diseases that develop rapidly, for example, simultaneously with Effezel.
The drug is not used to treat children under twelve years of age. Teenagers can use the cream unlimitedly if there is no individual sensitivity to the active substance.
During pregnancy, external use of the drug is allowed. In case of lactation, it is necessary to avoid applying it to the skin of the chest or not to feed the baby during therapy.
There is no information about an overdose of the drug "Klindovit."
Drug interaction
According to the instructions, “Klindovit” can interact with a number of drugs, which must be taken into account when developing a therapeutic course.
For example, erythromycin and clindamycin are antagonists that weaken each other's effects while using antibiotics and significantly extend the treatment time.
Cross-resistance is observed between lincomycin and clindamycin. If the patient has a history of resistance to the first substance, the use of clindovitis does not give any effect.
The effect of muscle relaxants is enhanced by Clindamycin. There is a possibility of neuromuscular transmission defects with prolonged sharing.
There is no information on the interaction of the drug and alcohol.
Breastfeeding and Pregnancy
The medication is approved for external use during pregnancy, when the intended benefits of treating a woman are higher than the potential danger to the baby. If it is necessary to use during lactation, breastfeeding is preferably minimized.
Side effects from this drug
According to reviews of “Klindovit,” side effects may occur on the background of its intake.
Local symptoms: there may be irritation in the area of application, itching, dry skin, burning, peeling, erythema, excessive secretion of fat by the skin, contact dermatitis.
Systemic reactions: pseudomembranous enterocolitis (can develop with systemic absorption of the active substance).
Typically, the drug is well tolerated by patients.
Contraindications to the use of this medication
A medication is not prescribed if there is:
- ulcerative colitis;
- Crohn's disease;
- pseudomembranous colitis (including history);
- excessive sensitivity to lincomycin or clindamycin.
Very carefully, the drug should be used by patients under the age of twelve (there are no data on efficacy and safety), during breastfeeding and in patients with a predisposition to allergic symptoms and the simultaneous use of muscle relaxants by the patient.
Special instructions for the use of the drug
When using Klindovit from acne, you should avoid contact of the medicine with the oral cavity and eyes, and after applying it, wash your hands thoroughly.
The drug can be used very carefully in patients up to the age of twelve (there is no information about the effectiveness and safety).
Analogs "Klindovita"
I must say that the analogues of the drug for the active component are Zerkalin, Klenzit and Dalacin.
Regarding belonging to a specific pharmacological group and mechanism of action, it should be noted that analogues are such drugs as Indoxil, Erythromycin-Ferein and Zenerit. The question of replacing this drug with another is discussed with a specialist.
Reviews about "Klindovit"
The drug is very popular among patients. Many people say that it helps slowly but effectively. Hence a lot of positive reviews about "Klindovit." They talk about him as one of the most effective means. Reviews about the gel often contain information about the appearance of allergic reactions due to intolerance to the drug. Therefore, patients should be careful when treating with a gel, since it is not suitable for everyone.
Why is Klindovit absent from pharmacies? This drug becomes a real salvation for young people, since it really helps to eliminate the inflammatory process and improve the condition of the skin. But recently, they are faced with the fact that it is impossible to purchase it in pharmacies. Some sources report that since 2014 the gel has not been produced, there is no data on the restoration of production.