Dextrose is actively involved in a wide variety of metabolic processes in the body. At the same time, a diverse effect on tissues and organs occurs: oxidation-reduction reactions and processes become more active and more intensive, and liver functions improve. The use of an aqueous dextrose solution makes up for the water deficit, making up for fluid loss.
Upon receipt of the drug “Glucose solution” in the tissue, its gradual phosphorylation occurs. The compound is converted to glucose-6-phosphate. The latter is directly involved in many stages of metabolic processes in the human body. An isotonic dextrose solution stimulates the acceleration of metabolic processes, provides a detoxifying effect, while glucose supplies a lot of nutrients to the body, replenishing energy losses.
Indications for use
The drug "Glucose solution", which is displayed in the urogenital system, has the following indications for use:
- sudden decrease in sugar level (hypoglycemia);
- A variety of infectious diseases that suppress the immune system and upset the metabolism;
- decompensation processes;
- liver pathology;
- pulmonary edema;
- increased bleeding (various hemorrhagic diathesis) and after heavy bleeding;
- state of shock;
- state of collapse (change (drop) in blood pressure).
In addition, the “glucose solution” is prescribed to balance the application of cardiac glycosides, as well as to replenish fluid loss.
Contraindications for use are:
- diabetes mellitus;
- hyperglycemia;
- hyperhydration;
- hyperosmolar coma;
- postoperative changes in glucose utilization;
- hyperlactacidemia.
Under careful medical supervision and with great caution, the drug is prescribed for diseases such as pulmonary edema, severe heart failure, anuria, oliguria, hyponatremia.
The medicine "glucose solution": instructions for use and dosage
The drug has a liquid form. Means “Glucose solution” 5% should be administered intravenously through the use of droppers, the maximum speed of which is up to 150 drops / min. The largest dose of the substance per day for adults will be 2000 ml. For a solution of 10%, a dropper is used at a speed of up to 60 cap / min with an identical maximum daily dose of the drug. 40 glucose solution is injected into the body at a speed of up to 30 drops / min (or 1.5 ml / kg / h).
The largest dose for adults per day is 250 ml. The dosage is selected by doctors depending on the detected nature of the metabolism. For example, a dose of 250-450 g / day for a normal type of metabolism can be reduced to 200-300 g for people with reduced metabolism.
When using glucose in medical practice and calculating its dosage, it is necessary to take into account the allowable amount of fluid introduced into the body - 100-165 ml / kg / day for children whose mass does not exceed 10 g, as well as 45-100 ml / kg / day for children weighing up to 40 kg.
The use of glucose in the background of diabetes is undesirable. Treatment is carried out under the constant control of the content of this substance in the blood and urine.
The drug "glucose solution": side effects
At the injection site of the glucose preparation, thrombophlebitis may develop. Side effects include fever, hyperglycemia, hypervolemia, acute left ventricular failure. Often there is a general deterioration in the state of the human body.
Special recommendations
The introduction of s / c 4-5 IU of insulin will provide a more complete and effective perception of glucose by the body. Insulin should be used in the calculation of 1 unit per 5 g of dextrose. The tool should be used carefully in combination with other drugs. without the appointment of a specialist, it is better not to use the drug in the treatment of the patient.