Grammidine is a tablet-shaped preparation with antibacterial action for topical use in the oral cavity and pharynx. The drug belongs to the pharmacological group of antibiotics. This article provides descriptions and instructions for using the simple drug Grammidin, which has one main substance, and the complex component, Grammidin with anesthetic.
Grammidine: instructions
Pharmacological action: The main effect is antibacterial. The instructions explain the therapeutic effect of the Grammidin preparation as follows: the permeability of the microbial cell wall increases, its stability is violated and then death occurs. In high concentrations, the drug has a bactericidal effect on many gram-positive and gram-negative microorganisms that are causative agents of infectious diseases of the oral cavity and pharynx. Grammidin tablets do not actually cause addiction to them sensitive microflora. With resorption, the process of salivation is activated, while the oropharynx is cleansed of inflammatory exudate and microorganisms.
Pharmacokinetics: Systemic absorption of the drug is low, so there is no data on the pharmacokinetics of the drug.
Release form and composition: Lozenges - white or white with a yellowish tinge. 1 tablet contains 1.5 mg of gramicidin C and auxiliary substances in the composition: sugar, milk sugar, methyl cellulose, calcium stearate. Packaging - polymer contour cell, contains 10 tablets. In a cardboard bundle - 2 packs.
Indications for use of the “Grammidin” remedy: the instruction prescribes a medicine for infectious and inflammatory diseases of the oral cavity and throat: acute pharyngitis, tonsillitis, tonsillitis, periodontitis, gingivitis, stomatitis.
Contraindications: Do not use with hypersensitivity to the components of the drug, breastfeeding.
Recommendations for use during pregnancy and the lactation period of the drug "Grammidin": The instruction warns of the need for caution in taking medication during pregnancy (consultation with a doctor is necessary). Side effects: during treatment, in some cases, allergic reactions to the components of the drug may occur.
Interaction: It has the ability to enhance the effect of other antimicrobial agents.
Method of use of the drug "Grammidine": The instruction prescribes the use of the drug locally, after eating, resorbing tablets in the oral cavity. After taking it, you must refrain from food and drink - 1-2 hours. Adults and children over 12 years of age: take 2 tablets. (the interval between them is half an hour) - 4 doses per day. Children under 12 years: 1-2 tablets. - 4 doses per day. The duration of treatment is an average of 5-6 days.
"Grammidin with anesthetic" - instructions
Dosage form: It is a preparation in the form of lozenges, with a taste: menthol or raspberry, or lemon, or black currant.
The composition of the drug "Grammidin with anesthetic": The instruction informs that each tablet includes: of the active substances - gramicidin C (antibacterial component) - 0.0015 g, lidocaine hydrochloride (anesthetic substance) - 0.01 g; of auxiliary substances - eucalyptus oil, menthol, citric acid, aspartame, hyprolose, calcium stearate, mannitol, the flavoring substance "Black Currant" or "Raspberry", or "Lemon".
Pharmacotherapeutic group of the drug: Combined drug containing a polypeptide antibiotic.
Pharmaceutical action: Similar to the simple "Grammidine" plus a local anesthetic effect. Lidocaine hydrochloride provides a local anesthetic effect on the inflamed mucous membranes of the mouth and throat. Anesthesia appears immediately at the time of resorption and lasts for 30-40 minutes.
Instructions for use, indications, contraindications and side effects are similar to the usual "Grammidine."
Storage conditions: In a place devoid of moisture, protected from the action of light rays, at a temperature of up to 25 ° C. Monitor the unavailability of medication for children. The shelf life of the drug "Grammidine" is 2 years.
Vacation conditions: Without a prescription.