Ordinary diarrhea is often perceived not as a problem, but as a kind of misunderstanding - they say it happened, it will pass by itself. However, the discomfort that literally bursts into a person’s life with an acute digestive upset is far from the main cause for concern. Thin stools are a symptom of an insidious ailment, which has become a consequence of various disorders in the body.
It must be understood that prolonged diarrhea dehydrates the body much faster than a thirty-degree heat. Functional imbalance of the gastrointestinal tract leads to the fact that the lion's share of the most useful trace elements and vitamins simply does not reach the “destination”. And over time, cells begin to experience a deficit of “building materials”. The outcome of this scenario is very deplorable, and if we are talking about a fragile children's body, the outcome can be fatal.
To neutralize such a threat, Stopdiar is well suited (reviews from both doctors and patients are very positive) - a highly effective antibacterial drug based on nitrofuran derivatives.
Release form
Suspension (syrup) bright yellow with a smell of banana; the original bottle is made of dark glass (container capacity - 125 ml, actual liquid volume - 90 ml). The container with the medicine is placed in a cardboard box in which there is a two-sided measuring spoon (5 ml and 2.5 ml).
In turn, Stopdiar tablets have a film membrane of a lemon shade and are packed in 24 units / blister. The geometry of the pills is standard.
The chemical composition and shelf life of the drug
The component base of the Stopdiar preparation is determined by the instructions for use as follows:
- in one dose of syrup (5 ml) contains 220 mg of nifuroxazide (active reagent);
- the same active substance in one tablet - 100 mg.
The suspension contains banana flavor, sucrose and anti-foam emulsion; in the pill - talc, potato starch and magnesium stearate.
Subject to the requirements of the temperature regime of storage (15-25 degrees Celsius), the syrup will be suitable for three years, tablets - for four.
Pharmacological action of the drug
Once in the gastrointestinal tract, nifuroxazide is practically not absorbed - it is released unchanged and thereby ensures the maximum concentration of the reagent in the problem area of the digestive system. Such a mechanism of contact with infection pathogens guarantees a high rate of manifestation of the therapeutic effect. At the same time, “Stopdiar”, analogues of which often “shock” the intestinal microflora, is distinguished by a tolerant attitude to “peaceful” bacteria. Being a derivative of 5-nitrofuran, nifuroxazide demonstrates activity against staphylococci and streptococci, and also disrupts the usual life cycle of salmonella, shigella and Escherichia coli.
Regular use of the suspension / tablet for acute diarrhea does not entail the development of resistant strains. Moreover, the effectiveness of therapy does not depend on the specificity of the acid-base medium in the intestinal lumen, or on the reaction of pathogenic microorganisms to antibiotics.
In an unbalanced digestive system, a decrease in the level of toxins after taking the Stopdiar drug (doctors' reviews indicate that this process is extremely fast) is achieved by inhibiting dehydrogenases and inhibiting the synthesis of protein compounds directly in bacterial cells.
Terms for appointment
Since the tablets / suspension "Stopdiar" (the use of the medication is normalized by the instructions) is an intestinal antiseptic, the following can serve as indications for its use:
- acute or chronic diarrhea caused by pathogenic pathogens that are sensitive to the active component (nifuroxazide);
- other gastrointestinal diseases of bacteriological origin.
Among the most pronounced symptoms of infectious diseases: loose stools, severe nausea, vomiting, permanent abdominal pain, persistent flatulence.
"Stopdiar": instructions for use of tablets
There is a direct connection between the form of the drug and those recommendations that the instruction informs about. "Stopdiar" - tablets that are intended for patients over 6 years old and are to be used without violating the integrity of the film membrane (chewing pills is not allowed). The regimen of taking the drug in this case does not depend on the diet or the schedule “breakfast - lunch - dinner”: the medication is taken every 6 hours until the symptom regresses. The optimal single dose for this age category is 2 tablets (8 units / day). The course should not exceed seven days, but the control period is limited to 72 hours: if after this time the patient does not feel better, you should immediately consult a doctor to adjust the therapy.
Instructions for use of the suspension
“Stopdiar” for infants (reviews of young mothers about the drug is very positive) is available in the form of a suspension, but with the same effect, the drug can be used in the treatment of older patients.
Syrup is given to the patient every 6-8 hours (again, without reference to food intake), while the medicine bottle is shaken vigorously in order to give the contents a uniform state.
A bilateral measuring spoon allows you to dose the medicine in a volume of 110-220 ml, which is very convenient, based on the recommendations of the instruction. The following standards are established for children, depending on age:
- from two to six months - 110-220 mg of syrup, twice a day;
- from six months to six years - 220 mg of active liquid, three times a day;
- older than six years - 220 mg suspension, four times a day.
Contraindications for the use of the medication
Stopdiar, reviews of which are based on the personal experience of many parents (the drug is considered one of the best solutions to the complex problem of childhood diarrhea), still can not be called a universal drug.
The purpose of this substance from a medical point of view is not justified if:
- the patient has all the signs of individual intolerance to the components;
- the patient is allergic to derivatives of 5-nitrofuran.
In addition, in the case of suspension, and in the case of tablets, there is a restriction on the minimum age of the patient - 2 months and 6 years, respectively. In addition, “Stopdiar” is a syrup (for children, the instruction introduces additional conditions of use), which is contraindicated in case of prematurity of the fetus, that is, if the young patient is 2 months old, but the birth was premature, the use of this medication can cause complications in the digestive tract.
Admissible side effects and special instructions
Side effects of the drug “Stopdiar” instruction (reviews on this topic are very rare, because, regardless of the form of release, the medication is well tolerated by people who suffer from diarrhea and concomitant disorders) is described as follows:
- increased diarrhea, aggravated by pain in the abdomen (interruption of therapy is not required in view of the transience of the described effect);
- shortness of breath, Quincke's edema, skin allergies (if such symptoms are detected, the drug is stopped).
Special instructions are a consequence of the biochemical characteristics of nifuroxazide. For example, the lack of susceptibility of the main component to metabolic processes sometimes leads to the fact that pathogens of a severe form of the disease cease to respond to the medication, and then the emphasis is on the parallel use of the profile antibiotic (although the use of Stopdiar with other antibacterial drugs is not recommended because of its reaction mechanism - total adsorption). Long-term antidiarrheal therapy based on nifuroxazide also puts forward demands on the diet - juices, spicy and rough foods, and thermally processed vegetables and fruits should be excluded from the diet.
Interaction "Stopdiar" with other drugs
Before using, first of all, you need to understand the principles of drug interaction of the drug "Stopdiar". The reviews (tablets and suspension, I must say, equally found support among the masses) often contain information that the intake of the described substance “put an end to” attempts to simultaneously get rid of several diverse ailments (that is, diarrhea passed, but other symptoms, suppressed medication remained).
As mentioned above, the reason for this is the specific mechanism of Stopdiar’s contact with other chemical compounds. Being a reagent not susceptible to absorption, the drug, nevertheless, is able to concentrate on its surface the active components of other pills and syrups, and can remove them from the body in an unsplit form.
The instruction says that the interval between taking "Stopdiar" and oral administration of another medication should be at least 2 hours.
Opinions and comments
About the drug "Stopdiar" reviews are mostly positive. There were no serious complaints about the effect of its components on the body of a child or an adult patient on thematic forums. Almost everyone who has come across a medication speaks of its effectiveness in stopping acute diarrhea.
But when compared with the more expensive analogue, Enterofuril (the same nifuroxazide is hidden under this trade name), the opinions of patients / parents regarding the pharmacological dynamics demonstrated by Stopdiar were somewhat divided. Probably, the notorious issue of price played its role again, because reputable doctors say that both drugs are equally effective and do not cause dysbiosis.