The human eye is a paired sensory organ that provides the function of vision and is able to perceive radiation (electromagnetic) in the light range of long waves. With age, as well as due to several other reasons, the functioning of the visual system deteriorates significantly. This leads not only to impaired vision, but also contributes to the development of various ophthalmic diseases.
Fortunately, today there are many drugs that are designed to treat eye diseases. One of them is the drug “Signicef”. The price of this tool will be presented below. You will also learn about whether he has contraindications and analogues.
Form, description, composition, packaging
In what form is the drug “Signicef” made? Eye drops are the most common form of this drug. They are a 0.5% clear solution of light yellow color.
The active component of the drug in question is levofloxacin, which is used in the form of hemihydrate. The composition of the drops also includes ingredients such as benzalkonium chloride, water for injection, sodium hydroxide, hypromellose, hydrochloric acid and sodium chloride.
This drug goes on sale in plastic dropper bottles, which are placed in cardboard packs.
Pharmacological properties
What is the Signicef medicine? Eye drops have antibacterial and antimicrobial properties. Their active component inhibits topoisomerase and DNA gyrase, and also inhibits DNA synthesis, preventing the crosslinking of DNA breaks and supercoiling.
It should be noted that levofloxacin provokes morphological changes in the cytoplasm, cell walls and bacterial membranes.
This drug adversely affects gram-positive flora and gram-negative aerobes. In addition, he actively acts against Chlamydia trachomatis.
Kinetic features of the drug
How does Signicef work? Eye drops, or rather their active ingredient, accumulate in the tear film after use. The concentration of the active substance in it in a short time reaches a high level and is held for 6 hours.
Indications for use of local funds
What does the Signicef drug help from? Reviews indicate that this tool works well:
- for the prevention of complications arising after surgery in the eyes;
- in the treatment of infectious diseases of the anterior segment of the eye, as well as the adnexa, which were caused by microorganisms sensitive to levofloxacin;
- in the local treatment of eye infections provoked by bacteria that are susceptible to levofloxacin.
Drug bans
The drug "Signicef", the price of which is quite high, should not be used for hypersensitivity to its elements, as well as for damage to the tendons that arose during the previous treatment with quinolones.
In addition, this medication is not prescribed for lactation, epilepsy and pregnancy. With extreme caution, drops are used at a minor age.
"Signicef": instruction
Eye drops "Signicef" is used immediately after the onset of the initial symptoms of the disease. The drug is instilled into the affected eyes in an amount of 1-2 drops with an interval of two hours.
The maximum dose of this medicine is 8 instillations per day. After 2 days, the medication is used in the same dosage, but only up to 4 times a day.
The duration of therapy with this agent depends on the characteristics and severity of the disease. Usually it is 5 days.
Mode of application
How should I use the drug "Signicef"? Eye drops are instilled behind the lower eyelid, after tilting the head back. So that the medicine does not enter the systemic circulation and the lacrimal duct, the internal corner of the visual organ is pressed with an index finger for 1-3 minutes.
The remnants of the drug are removed with a clean cloth, avoiding contact with the eyes.
In the event that the patient uses other ophthalmic agents, the interval between their use should be at least ¼ hour.
Side effects
Negative reactions after the use of this drug are very rare. Ophthalmic disorders such as pain and burning in the eyes, matting, swelling and erythema of the eyelids, worsening visual acuity, dry eyes, papillary conjunctival reaction, conjunctival follicles, chemosis, pruritus, conjunctival infection, photophobia are possible.
Analogs and cost
The price of the eye drops in question is about 700 rubles.
What can replace the drug "Signicef"? Analogs of this tool should be prescribed only by a doctor. These include the following drugs: Oftaquix, Levo, Abiflox, Zevocin, Glevo, Zolev, Levacept, Lebel, Levobax, Levobact, Levocacin, Levokilz, Levoksa, Levogrin, Novoks, Tigeron, Leflokad, Phloxium.
Reviews
Reviews about this drug are more positive. Consumers who use drops speak of their high effectiveness. They give a positive result for infectious diseases of the adnexa, as well as the anterior segment of the eye. In addition, this medication has established itself as a means for the prevention of complications after surgery on the visual organs.
As for the negative aspects, most patients name only the high price of the drug, as well as the inability to use it during pregnancy and breastfeeding.