Modern pharmacology provides for the production of analogues, various generics and substitutes for well-known drugs. This approach allows the patient to carry out the prescribed treatment with minimal cost. After all, many original drugs are much more expensive than their counterparts. This article will tell you about the Papaverine medication. Analogs of it will be presented as well. You will learn about the method of use of drugs and their purpose.
Description of the active substance and release form
Papaverine hydrochloride is an active component of the drug of the same name - "Papaverine". The medicine is in the form of tablets and a solution for injection. Also in drugstores you can get "Candles with papaverine." The cost of medicines differs in different regions and retail outlets.
The active ingredient refers to antispasmodics and vasodilators. It relieves spasm from smooth muscles, has a relaxing effect. Also, the drug helps to block phosphodiesterase and reduce the level of calcium in the cells. The drug "Papaverine", analogues of which will be described below, relieves vasospasm. Due to these actions, a therapeutic effect is obtained.
Papaverine hydrochloride: what helps?
What is the purpose of the drug? To answer this question, you need to study the instructions for use. Indications for the use of the medication are the following cases:
- spasm of the abdominal organs (renal or intestinal colic, cholecystitis, pylorospasm);
- bronchospasm, angina pectoris (spasm of the heart muscle);
- headaches caused by narrowing of the vessels of the brain;
- premenstrual pain and algodismenorrhea;
- risk of premature birth or miscarriage during pregnancy.
The medication is used in surgery to prepare for surgery. Here it is used for sedation in combination with other means. If you have been prescribed Papaverine Hydrochloride, which helps, you should ask your doctor. The doctor will tell you in detail about the medicine and give recommendations on its use.
How to take the medicine "Papaverine"?
The dose of the drug and its form of release is prescribed individually. These factors depend on the condition of the patient and his complaints.
Adult patients are prescribed 0.04-0.06 grams of active ingredient up to 5 times a day. This serving is taken in pill form. "Papaverine" - tablets that are available with a content of 0.04 grams of papaverine hydrochloride. If injection is intended, then the medicine is used in a dose of 1-2 ml up to 4 times a day. "Papaverine" in ampoules contains 2 ml of the main component. With intravenous administration, the drug is pre-diluted with a solution of sodium chloride and supplied dropwise.
Rectal suppositories are more often prescribed to pregnant women. The dose and duration of therapy is selected depending on the condition of the expectant mother. How to use papaverine candles? The medicine is injected into the rectum after a preliminary act of defecation, 1-2 suppositories up to three times a day.
Drug Substitutes: Absolute and Indirect
What are the analogues of the drug "Papaverine"? There are medicines that have the same composition. In them, the main component is papaverine hydrochloride. The trade names for these products are: Papaverine Bufus, Papaverine Hydrochloride MS, Baby Papaverine 0.01, and so on. The medicine “Papazol” contains the active substance papaverine hydrochloride in its composition, but another component is also present in it.
The following drugs can be attributed to indirect substitutes for the Papaverine drug (analogues): No-shpu, Renalgan, Drotaverin, Pulmicort, Foradil Combi, Spazmobru, Spazmalgon, Analgin, "Paracetamol", "Ibuprofen" and many others. All of them have an analgesic effect. Some of the drugs relieve spasm and eliminate fever. Consider the main in more detail.
The medicine "Papazol"
If you need to replace "Papaverine" (tablets), then you can buy the medicine "Papazol". It is produced in tablets of 10 pieces per blister. The drug contains papaverine hydrochloride and dibazole. Additional components: talc, powdered sugar, potato starch, stearic acid.
The medicine “Papazol” is prescribed for spasms of the vessels of the brain and peripheral vessels. Like Papaverine, the analogue is used to eliminate spasms of the abdominal organs. Contraindication to the use of the drug is obstructive bronchitis, epilepsy, some heart diseases and children under one year of age.
The medication is prescribed for 1-2 tablets up to 3 times a day. The duration of therapy is from two weeks to a month. For children, the medication is selected in an individual dosage.
Drugs "Drotaverin" and "No-shpa"
Other analogs of the Papaverine preparation will be: No-shpa forte, No-shpa and Drotaverin. The active substance of all these drugs is drotaverine hydrochloride. It has an antispasmodic, vasodilating effect. The drug relieves tone, reducing muscle activity. Medicines are available in the form of tablets and injection. The No-Shpa and Drotaverin preparations in the form of tablets contain 40 mg of drotaverine hydrochloride. One ampoule includes 2 ml of solution (40 mg of active ingredient). If we consider the drug "No-shpa forte", then it contains a double dose (80 mg of drotaverine hydrochloride) per tablet.
Indications for the use of drugs are spasms of blood vessels, abdominal organs, gynecological diseases (including the threat of termination of pregnancy). It is forbidden to use drugs in various forms for renal, liver and heart failure, children under one year of age and with a deficiency of lactose.
The drugs "No-spa" and "Drotaverin" are taken at 40-80 milligrams three times a day. Injections are administered intravenously or intramuscularly in a volume of 40-80 mg of drotaverine hydrochloride. The daily dose should not be more than 240 milligrams of the active ingredient.
Means "Renalgan"
To some extent, this medicine can be called a substitute for Papaverine. The drug "Renalgan" is available in ampoules and tablets. The active substances of the medication are: metamizole sodium, fenpiverinium bromide and pitophenone hydrochloride. The tool has an analgesic and antispasmodic effect, as well as an antipyretic and anti-inflammatory effect. The fenpiverinium bromide component promotes additional relaxation of smooth muscles.
The “Renalgan” remedy is prescribed for cramps of the ureter, renal, intestinal colic, during inflammatory infectious diseases. The medication can be used to eliminate fever and pain of different localization. You should not use the drug for certain diseases of the blood, heart and kidneys. It is forbidden to use the medication during pregnancy and lactation, as well as in children under 5 years old.
The method of use of the drug is determined by the doctor. In the absence of separate recommendations, the medicine is prescribed in a dose of 1-2 tablets. Multiplicity of use - up to three times a day. Injections are prescribed individually depending on the condition of the patient.
Inhalations "Foradil Combi"
The drug "Foradil Combi" is available in capsules intended for inhalation. Unlike other similar solutions, the medication does not provide for the use of separate inhaler devices. All that the patient needs for the procedure is in the package. The main active ingredient in the drug is budesonide. One capsule contains 200 or 400 micrograms of the component.
Indications for administration of the drug are respiratory tract spasms: bronchitis, pneumonia, asthma, obstruction, spastic cough. The medication helps to expand the lumen of the bronchi and normalize breathing. It is contraindicated to use the inhalation agent “Foradil Combi” for children under 6 years of age and for pregnant (lactating) women. It is not recommended to prescribe such therapy to patients with pulmonary tuberculosis and to persons with hypersensitivity to the composition of the drug.
Dosage is determined depending on the pathology. For adult patients, the maintenance dose of the drug is 200 to 400 mcg twice a day. It is recommended to use the minimum portion for treatment. If a large dosage is selected, then after improving the patient's condition, it should be reduced.
Spazmobru capsules
Replace the medicine “Papaverine” with the medication “Spazmobru”. The tablets contain hyoscine butyl bromide. The drug has an antispasmodic effect on the abdominal organs. The active ingredient is poorly absorbed in the gastrointestinal tract. In the pharmacy network, you can also purchase the Spazmobru solution. It is intended for intramuscular, subcutaneous or intravenous administration.
The purpose of the drug is made for the following diseases: cramps of the digestive system and organs of the abdominal cavity; nausea and vomiting; gynecological diseases and pathologies of the urinary system. The drug is used for sedation, in order to prepare the patient for various diagnostic procedures. It is contraindicated to use the remedy for glaucoma, prostate diseases, arrhythmias and tachycardia.
Adult patients "Spazmobru" is prescribed in a dose of 10 mg up to 5 times a day. The maximum daily portion is 100 mg of the active substance. For children, the dose of medicine is determined depending on body weight. The solution for injection is prescribed in an individual dosage.
What to choose?
What should the patient choose from the proposed medicines? How to replace "Papaverine" in ampoules, tablets and suppositories? This issue must always be addressed with a doctor. If you choose the wrong substitute, then the effect of the treatment will not be as expected. Which means to give preference to depends on the testimony. Be sure to study the instructions for the drug, get acquainted with all the indications and limitations. Be sure to read about adverse reactions. If you have any, urgently contact a doctor for advice.
Often antispasmodics are prescribed in combination with other drugs. Be sure to follow the order of taking certain drugs. For more information about this, contact your doctor.
To summarize
All drugs have their own analogues. If you do not have special indications for replacing therapy, then it is worth using the medication recommended by the doctor. Do not self-adjust appointments. This can cause very unpleasant consequences. It is strictly forbidden to replace the Papaverine with any other during pregnancy.
The original medicine, like many of its substitutes, is available without a prescription. Store the preparations according to the conditions indicated on the package. Do not use medicines after the expiration date. Take care of yourself and be treated correctly. Good luck!