The drug "Dufaston", with a delay in menstruation, helps to establish hormonal processes in the body, contains a derivative of progesterone - dydrogesterone. This synthetic substance, like natural hormone, affects the maturation of the endometrium. It is this layer of the uterine membrane that changes actively during the menstrual cycle. That is why a drug based on this active substance is effective in treating menstrual irregularities. It can also be used in the treatment of patients with progesterone deficiency, leading to infertility, habitual abortion, the development of severe premenstrual syndrome. With the help of this drug, the effect of proliferative estrogens on the endometrium of women during menopause can be reduced.
Synthetic progestin, devoid of many side effects that are observed, for example, when taking the drugs "Ciproteron", "Medroxyprogesterone", is the drug "Duphaston." With a delay in menstruation, it contributes to the onset of ovulation and the release of an egg from a mature follicle. Side effects of a virilizing or masculinizing nature are not characteristic for this drug. The drug can be used if there are indications in the treatment of even pregnant women, making up for the deficiency of the natural hormone in the body. During lactation, it is still worth abandoning it, since the medication passes into breast milk.
The drug "Duphaston" with a delay in menstruation can be prescribed in various situations. This may be a therapy aimed at correcting an irregular cycle, amenorrhea, dysmenorrhea. It is also possible to use such a drug in combination replacement therapy. At the same time, it is combined with estrogen and is prescribed in the second half of the cycle. After preliminary estrogen therapy, this pharmaceutical agent promotes the formation of secretory endometrium and provokes the onset of menstruation.
The drug "Dufaston" with a delay in menstruation is prescribed in a dosage of 10 mg. The drug is used 2 times a day during the last 14 days of the menstrual cycle (provided that it lasts 28 days). The treatment of dysmenorrhea depends on some features of the patient’s clinical picture and lasts 3-6 months on average. In the case of prescribing a drug with an irregular cycle in premenopausal women with a decrease in the duration of the luteal phase, the same dosage is used, however, administration is carried out starting from the 11th and ending on the 25th day from the beginning of the previous cycle.
Duphaston medication for menstruation is used in combination with estrogen preparations, since with amenorrhea, dysmenorrhea, the balance of these hormones is usually usually disturbed. In addition, with combination therapy, it suppresses the proliferative effect of estrogen on the inner layer of the uterus. Therefore, the drug can be prescribed to women with risk factors for the development of cancer in this tissue. However, it is worth remembering that the drug is contraindicated in patients with Rotor syndrome and Dabin-Johnson syndrome.
If necessary, call your period with Duphaston, you must carefully follow the doctor’s instructions and the dosage of the drug. If metrorrhagia occurs, dose adjustment is necessary, as a rule, upward. During treatment, an ultrasound scan is required to help identify the positive or negative effect of the drug on the thickness and other characteristics of the endometrium. Also, the purpose of this drug should not provoke a refusal to further study the causes of menstrual irregularities.