The liver is an important organ that collects harmful substances that can cause serious damage to health. Toxins, as a rule, enter the human body with food, as well as alcohol, medicines and dirty air, so the body is under heavy stress every day.
To restore the full functioning of the liver, hepatoprotectors that regenerate organ cells can be used. One of them is Phosphogliv. It is widely used in the elimination of liver diseases. Which is better manufacturer "Phosphogliv" and "Phosphogliv Forte"?
Characteristic
"Phosphogliv" refers to hepatoprotectors and has a pronounced immunomodulating and antiviral effect. The medication is in the form of capsules for oral use.
There are two manufacturing countries "Phosphogliv" - Germany and Russia. Capsules produced by a German company are gelatinous, orange-black. Inside the capsules is a white powder with a specific aroma. The drug is placed in blisters of 10 pieces. There are 30 capsules per pack.
Country of origin "Phosphogliv Forte" - Russia. The medication is also in the form of capsules. They are also gelatinous with a solid structure. Their contents are a pasty mass with a characteristic odor from orange to light yellow in color.
The drug is placed in contour cells of 10 pieces, in total there are two, three, five blisters in the package. The medication is also placed in plastic containers or plastic cans of 50, 100, 200 or 300 capsules.
The number of active ingredients in the preparations is different. For example, in Phosphogliv, the manufacturer, which is Germany, the concentration will be as follows:
- phospholipids - 65 mg;
- trisodium salt of glycyrrhizic acid - 35 mg.
Additional components:
- cellulose;
- salt of carbonic acid and calcium;
- talc;
- a salt of calcium and stearic acid;
- anhydrous silica.
The manufacturer in the instructions for use with "Phosphogliv Forte" indicated the following concentration of active substances:
- phospholipids - 300 mg;
- lipoid - 400 mg;
- trisodium salt of glycyrrhizic acid - 65 mg.
As additional substances are:
- ethanol;
- food supplement E321;
- sunflower oil.
Pharmacological actions
Licorice root was most often used in Chinese as well as Indian and ancient medicine. One of the main substances contained in it is triterpene glycoside glycyrrhizin. It has a huge number of useful properties:
- Antiviral activity.
- Immunomodulatory effect.
- Antioxidant effect.
- Membranotropic action.
These properties make it indispensable in eliminating liver diseases. In addition, the protective effect of glycyrrhizic acid in fatty liver disease has been established. With an increase in the level of aliphatic carboxylic acids in the blood in the liver, biochemical processes are launched that lead to the accumulation of excess.
Glycyrinates prevent it accumulation and protect parenchyma cells from death. Phosphatidylcholine can directly protect hepatocytes from ethyl alcohol and carbon tetrachloride.
Indications
"Phosphogliv" is intended for oral use, the main indications for the prescription of the drug are:
- Liver steatosis.
- Lesions of the body, which are accompanied by functional disorders in its work.
- Viral hepatitis.
- Cirrhosis of the liver.
- Psoriasis.
The medication is highly effective as a therapeutic and prophylactic drug to restore the functioning of the liver after prolonged therapy with antimicrobial or any other drugs.
Contraindications
Before starting treatment, the patient should be familiar with the instructions for use, since the capsules have a number of specific prohibitions:
- Pregnancy.
- Increased drug sensitivity.
- Lactation.
- Autoimmune pathological process, which is based on the formation of antibodies to phospholipids.
- Children under 12 years old.
According to the instructions for use and reviews of "Phosphogliv", it is known that the following conditions are considered relative restrictions on the use of the drug:
- Hypertension is a syndrome of increased systolic and diastolic blood pressure.
- Portal hypertension - high blood pressure in the portal vein, provoked by impaired blood flow in the portal capillaries, as well as in the hepatic veins and inferior vena cava.
- The presence of chronic diseases.
Mode of application
Capsules are taken orally during meals. The drug must be swallowed immediately, without opening, washed down with water.
Small patients from 12 years old and adults are prescribed 2 capsules three times a day. The duration of therapy varies from 3 months to six months, if necessary, the doctor can adjust this period.
Pregnancy and breastfeeding
There is no experience using Phosphogliv among women in the situation. Studies regarding the safety of drugs for the fetus have not been carried out, therefore, capsules are not recommended for women during pregnancy.
There is no information whether the active components of Phosphogliv with milk are excreted and how this can affect the baby. Given the lack of information about the safety of the drug, oral administration of capsules to women during lactation is not recommended. If treatment with medicine is necessary, it is necessary to resolve the issue of transferring the baby to artificial mixtures.
Side effects
According to the instructions and reviews for "Phosphogliv", it is known that the drug, as a rule, is well tolerated by people, but in exceptional situations with increased sensitivity to substances, certain negative reactions may occur:
- Loss of appetite.
- Bitterness in the oral cavity.
- Nausea.
- Vomiting.
- Violation of the stool.
- Flatulence is a pathological condition of the body that occurs due to excessive gas formation and accumulation of gases in the gastrointestinal tract.
- A sudden increase in blood pressure.
- Peripheral edema - a condition of the limbs, which is characterized by the accumulation of fluid in the soft tissues.
- Itching of the skin.
- Rashes.
- Urticaria is a skin disease, dermatitis of mainly allergic origin, which is characterized by the rapid onset of severely itchy blisters.
If one or more side effects occur, you must stop using the medication and consult a doctor. If you accidentally ingest a large number of capsules, you need to provoke vomiting and take activated charcoal or other enterosorbent.
Interaction
The drug "Phosphogliv" can be used simultaneously with antibacterial agents, bacteriostats, as well as antiviral medications. Capsules should not be used together with adsorbents and antacids, since these drugs reduce the absorption of active ingredients and reduce its pharmacological effect.
There is no information about any other interaction, but if a person uses drugs or biologically active additives, it is important to warn a specialist about this.
Features
During therapy with the drug "Phosphogliv", patients with hypertension should be especially careful, because when using capsules, short-term sharp increases in blood pressure are likely.
The drug does not affect the functioning of the nervous system. There is no experience of taking the medication among patients under 12 years of age, and safety for the child's body has not been fully studied.
"Phosphogliv" or "Phosphogliv Forte" - which is better? Of course, this question is better to ask a specialist. A doctor-hepatologist or gastroenterologist after the examination will help to choose the right medication and prescribe a course of therapy.
It is impossible to say which of these drugs is better, since the concentration of the drug should be selected taking into account body weight, as well as age and diagnosis.
Analogs
The following drugs have similar pharmacological effects with capsules:
- Essential Forte.
- Energylive.
- Gepabene.
- "Pumpkin".
- "Carsil."
Before replacing the original medication with a generic, you should contact a medical institution to exclude the possibility of adverse reactions.
Storage conditions
Capsules are dispensed from pharmacies without a doctor’s prescription. Keep the medicine package in a cool, dry place, away from children. Shelf life is 36 months. At the end of this time, the drug must be disposed of.
Reviews
In most situations, patients talk about the drug as an effective tool in the fight against liver diseases. It helps eliminate unpleasant symptoms.
This was also noted in patients with serious diseases, for example, with hepatitis, “Phosphogliv” copes with the problem perfectly. In addition, opinions confirm that the medication improves the condition of the skin. In addition, the medicine is relatively inexpensive.
A small number of negative responses due to the fact that not in all situations from the use of the drug can achieve a positive effect.
Reviews of experts on "Phosphogliv" and "Phosphogliv Fort" are good. Medicines are often used to eliminate liver disorders of various origins. It is noted that this drug is effective in hepatitis C.
In addition, the medication is able to positively affect the condition of patients with certain skin lesions. For example, it is prescribed in most situations with psoriasis.
In addition, specialists respond positively about the drug as a hepatoprotector, which is used for any toxic liver disorders. In these conditions, the medication stabilizes biochemical analyzes, improves overall well-being.
Dermatologists who use the medicine to eliminate various skin diseases respond positively to Phosphogliv. For many women, the drug helped get rid of acne and acne, stabilizing the liver and increasing its ability to neutralize toxic substances.
Conclusion
Both drugs are in capsule form and contain the same composition of active ingredients. It includes phosphatidylcholine and the sodium salt of glycyrrhizic acid. The difference between Phosphogliv and Phosphogliv Forte is the amount of substances. Compared with the first drug in the second there are more.
"Phosphogliv Forte" is a hepatoprotector based on phospholipids and glycyrrhizic acid, which is used in pathological processes in the liver of various origins. The drug effectively regenerates damaged cells with toxic hepatitis and fatty hepatosis, when liver cells are damaged.
If something is different between these medicines, it is the concentration of active substances. In this situation, the standard variety of the drug contains 65 mg of phosphatidylcholine and lipoid. And in "Phosphogliv Fort" - 300 mg. The last medicine also contains phospholipid.
A similar situation is observed, in addition to this, and with another, no less important, active component. It is sodium glycyrrhizinate, which in the preparation of the classic "Phosphogliv" contains 35 milligrams, while in "Phosphogliv Fort" - already 65 mg.
As for the spectrum of effects of these two drugs, their pharmacological properties, they are exactly the same. As a result, “Phosphogliv” differs from “Phosphogliv Forte” only in some, not particularly important points. Other than that, completely different and cost. The price of Phosphogliv Forte varies from 400 to 1400 rubles, and the price of Phosphogliv Fort - from 800 to 1900 rubles.