With age, estrogen levels in a woman's body begin to decrease. This leads to a number of symptoms that cause discomfort. This is night sweating, an increase in subcutaneous fat, hypertension, dry genital mucosa, and urinary incontinence. Hormone replacement therapy (HRT) will help to avoid such an unpleasant condition . Medications can remove the symptoms of menopause and reduce the risk of complications associated with the menopause. Such drugs include Klimonorm, Klimadinon, Femoston, Angelik. With extreme caution, HRT should be performed with menopause. A new generation of drugs can be prescribed only by a qualified gynecologist.
The release form of the drug "Klimonorm"
The medicine refers to anti-climacteric drugs. It is made in the form of a dragee of two types. The first type of dragee is yellow. The main substance in the composition is estradiol valerate 2 mg. The second type of dragee is brown. The main component is estradiol valerate 2 mg and levonorgestrel 150 mcg. The medicine is packaged in blisters of 9 or 12 pieces each.
With the help of this medication, HRT is often performed with menopause. New generation drugs reviews are in most cases good. Side effects do not develop if you adhere to the doctor's recommendations.
The effect of the drug "Klimonorm"
"Klimonorm" is a combined drug that is prescribed to eliminate the symptoms of menopause and consists of estrogen and gestagen. Once in the body, the substance of estradiol valerate is converted to estradiol of natural origin. The levonorgestrel substance added to the main drug is the prevention of endometrial cancer and hyperplasia. Due to the unique composition and special regimen, it is possible after treatment to restore the menstrual cycle in women with an unremoved uterus.
Estradiol completely compensates for the natural estrogen in the body at the moment when menopause occurs. Helps to cope with vegetative and psychological problems that arise during menopause. You can also slow down the formation of wrinkles and increase the collagen content in the skin during HRT with menopause. Drugs help reduce total cholesterol and reduce the risk of bowel disease.
Pharmacokinetics
When administered, the medicine is absorbed in the stomach in a short period. In the body, the drug is metabolized with the formation of estradiol and estrol. Within two hours, the maximum activity of the drug in plasma is observed. The substance levonorgestrel is almost 100% bound to blood albumin. It is excreted in the urine and a little with bile. With special attention, it is worth choosing medications for HRT with menopause. Drugs at level 1 are considered potent and can significantly improve the condition of the fairer sex after 40 years. The drug "Klimonorm" also belongs to medicines from this group.
Indications and contraindications
The drug can be used in the following cases:
- hormone replacement therapy for menopause;
- involutional changes in the skin and genitourinary system;
- insufficient estrogen during menopause;
- preventive measures of osteoporosis;
- normalization of the monthly cycle;
- treatment process with amenorrhea of the primary and secondary type.
Contraindications:
- bleeding not associated with menstruation;
- breast-feeding;
- hormone-dependent precancerous and cancerous conditions;
- mammary cancer;
- liver disease
- acute thrombosis and thrombophlebitis;
- hypersensitivity to components;
- hypotension;
- diseases of the uterus.
HRT is not always indicated for menopause. New generation drugs (the list is presented above) are prescribed only if the menopause is accompanied by a significant deterioration in the well-being of the woman.
Dosage
If there are still periods, then treatment should begin on the fifth day of the cycle. With amenorrhea and menopause, the treatment process can begin at any time of the cycle, with the exception of pregnancy. One pack of Klimonorm medicine is designed for a 21-day intake. The tool is drunk according to this algorithm:
- the first 9 days a woman takes a yellow dragee;
- the next 12 days - brown dragees;
After treatment, menstruation appears, usually on the second or third day after taking the last dose of the drug. There is a break for seven days, and then you need to drink the next package. Dragees should be taken without chewing, and washed down with water. It is necessary to take the drug at a specific time, not missing.
It is imperative to adhere to the HRT regimen with menopause. New generation drugs reviews may have negative ones. It will not be possible to achieve the desired effect if you forget to take the dragee in a timely manner.
In case of an overdose, unpleasant phenomena such as upset stomach, vomiting and bleeding that are not associated with menstruation can occur. There is no specific antidote for the drug. In case of an overdose, symptomatic treatment is prescribed.
The drug "Femoston"
The medication belongs to the group of anti-climacteric drugs. Available in the form of tablets of two types. In the package you can find a dragee of white color with a film shell. The main substance is estradiol in a dose of 2 mg. Also, the first type includes gray tablets. The composition contains estradiol 1 mg and dydrogesterone 10 mg. The product is packaged in blisters of 14 pieces each. The second type includes pink tablets, which contain 2 mg estradiol.
With the help of this tool, replacement therapy is often carried out. With special attention are selected, if we are talking about HRT with menopause, drugs. Reviews Femoston has both positive and negative. Good sayings still prevail. A drug can eliminate many menopausal manifestations.
Act
"Femoston" is a two-phase combination drug for the treatment of postmenopause. Both components of the drug are analogues of the female sex hormones progesterone and estradiol. The latter replenishes the supply of estrogen during menopause, removes the symptoms of a vegetative and psycho-emotional nature, and prevents the development of osteoporosis.
Dydrogesterone is a progestogen that reduces the risk of developing hyperplasia and uterine cancer. This substance has estrogenic, androgenic, anabolic and glucocorticoid activity. When it enters the stomach, it is rapidly absorbed and then completely metabolized. If HRT is indicated for menopause, Femoston and Klimonorm preparations should be used first.
Indications and contraindications
The medication is used in such cases:
- HRT during menopause and after surgery;
- prevention of osteoporosis associated with menopause
Contraindications:
- pregnancy;
- lactation;
- breast cancer
- tumors of a malignant nature that are hormone-dependent in nature;
- porphyria;
- thrombosis and thrombophlebitis;
- hypersensitivity to components;
- diabetes;
- hypertension;
- endometrial hyperplasia;
- migraine.
It will help to improve the well-being of HRT with menopause. Drug reviews are mostly positive. However, they cannot be used without prior consultation with a doctor.
Dosage
Femoston tablets containing 1 mg estradiol are taken once a day at the same time. Treatment is carried out according to a special scheme. In the first 14 days, you need to take white tablets. In the remaining 14 days - a medicine of a gray tint.
Pink tablets with 2 mg estradiol are drunk within 14 days. Women who have not yet had their menstrual cycle should begin treatment on the first day of bleeding. For patients with an irregular cycle, the drug is prescribed after a two-week treatment with Progestagen. In the absence of menstruation, everyone else can start drinking the medicine on any day. It is necessary to follow the treatment regimen in order to obtain positive HRT results with menopause. Preparations of a new generation will help keep a woman feeling well and prolong her youth.
The drug "Klimadinon"
The medicine refers to a means to improve well-being during menopause. It has a phytotherapeutic composition. Available in the form of tablets and drops. Pink tablets with a brown tint. The composition contains a dry extract of tsimitsifugi 20 mg. The drops contain a liquid extract of cimicifuga 12 mg. The drops have a light brown tint and the smell of fresh wood.
Indications:
- vegetative-vascular disorders associated with symptoms of menopause.
Contraindications:
- hormone-dependent tumors;
- hereditary lactose intolerance;
- alcoholism;
- hypersensitivity to the components.
Carefully it is necessary to study the instructions before starting HRT with menopause. Drugs (patch, drops, pills) should be used only on the recommendation of a gynecologist.
The drug "Klimadinon" is prescribed one tablet or 30 drops twice a day. It is advisable to conduct therapy at the same time. The course of treatment depends on the individual characteristics of the body.
The drug "Angelique"
Refers to the funds that are used to treat menopause. Available in the form of gray-pink tablets. The composition of the drug includes estradiol 1 mg and drospirenone 2 mg. The product is packaged in blisters, 28 pieces each. The specialist will tell you how to properly carry out HRT with menopause. New generation drugs cannot be used without prior consultation. Hormone therapy can be beneficial or harmful.
The medication has the following indications:
- hormone replacement therapy during menopause;
- prevention of osteoporosis with menopause.
Contraindications:
- vaginal bleeding of unknown origin;
- mammary cancer;
- diabetes;
- hypertension;
- thrombosis.
During menopause, many gynecologists recommend HRT with menopause. A new generation of drugs is an excellent solution for women after 45 years.
Dosage of the drug "Angelique"
One package is designed for 28 days of admission. Take one tablet daily. It is better to drink medicine at the same time, without chewing and washing down with water. The therapy should be carried out without omissions. Neglecting the recommendations will not only not bring a positive result, but can also provoke vaginal bleeding. Only proper adherence to the scheme will help normalize the menstrual cycle during HRT with menopause.
Preparations of a new generation ("Angelik", "Klimonorm", "Klimadinon", "Femoston") have a unique composition, thanks to which it is possible to restore female hormonal imbalance.
Klimara patch
This medication is available in the form of a patch containing 3.8 mg of estradiol. The oval-shaped product is glued to the area of the skin hidden under the clothes. In the process of using the patch, the active ingredient is released, improving the condition of the woman. After 7 days, the product must be removed and a new one glued to another site.
Side effects from the use of the patch develop quite rarely. Despite this, the hormonal agent must be used only after consultation with the doctor.
Reviews about the means of HRT
A new generation of drugs that are used in hormone replacement therapy can restore women's health during menopause. They have good reviews from women over 45. Medications in a short period relieve patients from autonomic and psychoemotional disorders, are also an excellent prevention of osteoporosis. All products are well tolerated and not addictive.
Experts note that after the treatment, women have a normal menstrual cycle, the skin acquires a healthy color and becomes smooth and tender. Blood cholesterol is reduced. Small wrinkles are smoothed out on the face, the patients have a great mood and a surge of strength. Pills and dragees are easy to take, according to the scheme. All of them have a protective shell that does not irritate the gastric mucosa. Hormone patch is also popular.