The drug "Kapoten" - a drug that is an inhibitor of the angiotensin-digesting enzyme, refers to synthetic medicines. It contains the active element captopril and such auxiliary substances as stearic acid, lactose, microcrystalline cellulose, and corn starch. Basically, for violations of the heart, the drug "Kapoten" is prescribed. What exactly is it used for? Let's look at the article.
Release form
A medicine is produced in the form of square biconvex tablets of white color. Each tablet contains 25 mg of captopril. In one blister - 10 or 14 tablets. In a pack - 2 or 4 blisters.
The drug "Kapoten": what is it used for?
The medication is prescribed for such conditions as:
- diabetic nephropathy, which develops due to diabetes mellitus (type 1);
- post-infarction period with impaired functioning of the left ventricle;
- arterial hypertension (including renovascular).
In chronic heart failure (CHF) , the Kapoten medication is one of the means of combination therapy.
pharmachologic effect
In a relatively short time, you can lower the pressure if you take this medicine (for pressure “Kapoten” is prescribed quite often). At the same time, myocardial oxygen demand decreases, and tachycardia does not occur. The maximum therapeutic effect is achieved, usually after an hour. The optimal value can be achieved with prolonged use of the medication after a few weeks. With diabetic nephropathy, the use of the drug helps to slow down the development of kidney pathology.
Contraindications to the use of the medication
From what Kapoten tablets are prescribed, we found out, now we will deal with contraindications to the use of this drug. Do not prescribe a medicine if the patient has the following conditions:
- stenosis of the aortic orifice and other similar obstructive pathologies in which outflow of blood is difficult from the left ventricle;
- hyperkalemia
- recovery period after kidney transplant surgery;
- severe violations of the liver and kidneys;
- angioedema ;
- bilateral renal artery stenosis and arterial stenosis of one (single) kidney in the presence of progressive azotemia.
- hypersensitivity to the components of the drug;
- pregnancy, breastfeeding.
The drug can not be used in pediatrics and children under 18 years of age, since the necessary clinical trials have not been conducted.
With caution, the drug "Kapoten" is used in such conditions:
- primary hyperaldosteronism;
- severe autoimmune diseases of the connective tissue;
- inhibition of bone marrow hematopoiesis (since the development of agranulocytosis and neutropenia is possible);
- coronary heart disease or cerebral ischemia;
- following a salt-free or low-salt diet;
- in old age.
Instructions for use
The drug "Kapoten", no matter what it was prescribed, is taken an hour before eating. The dose of the drug is determined individually and depends on the type and severity of the disease.
The initial dose for hypertension is 12.5 mg, take the medicine 2 times a day. Gradually increase the dose, the interval between increases can be several weeks. With moderate hypertension, take 2 tablets of the drug twice a day, 4 tablets can be taken as much as possible. In severe arterial hypertension, the initial dose is 12.5 mg twice a day, gradually the amount is increased to the maximum dose - three tablets three times a day.
With CHF, a medicine is prescribed if there is no positive effect from taking diuretics. Initially, take 6.25 mg up to three times a day, after - three times a day, 25 mg each, the maximum dose for 24 hours is 6 tablets. The dose is recommended to be increased every 2 weeks.
In the post-infarction period in a stable state, 6.25 mg are taken per day. Gradually, you can bring the dose to the maximum.
With diabetic nephropathy per day, take up to 3-4 tablets, divide the specified amount into 2-3 doses.
In case of impaired renal function in moderate or mild form, take 75-100 mg per day, in severe form - 2 tablets per day.
Those who used the Kapoten drug against pressure leave reviews mostly positive. However, this is only subject to the observance of all the doctor's prescriptions.
Side effects
The medication "Kapoten" can have a side effect, which is manifested:
- peripheral edema, orthostatic hypotension, tachycardia;
- bronchospasm or pulmonary edema;
- angioedema of the mucous membranes, lips, tongue, face, larynx, pharynx, limbs;
- drowsiness, headache, ataxia, impaired vision, dizziness;
- agranulocytosis, neutropenia, thrombocytopenia, anemia.
Finally
After reading this article, you learned more about the Kapoten preparation: what they use, how to use it correctly, possible side effects. Before using the medicine, be sure to consult a specialist.