In the article, we consider the antibiotics used for gastric ulcer, a disease characterized by frequent relapses and a tendency to progression. And such manifestations are not limited to just one problem. Along with the stomach, the duodenum and other organs of the gastrointestinal tract are involved in the pathology, there is a likelihood of developing adverse complications that threaten health.
In the treatment of this condition, the use of a variety of medications is recommended. Quite often, with ulcerative lesions, doctors prescribe antibiotics for the stomach, which help to relieve symptoms and rapid recovery. In particular, the patient’s recovery depends on the right medicine.
The use of antibacterial drugs
In order to determine the appropriate treatment regimen for peptic ulcer using antibiotics for the stomach, a preliminary examination of the gastrointestinal tract should be performed. The selection of the optimal course of therapy is facilitated by laboratory tests of feces, blood, biopsy, ultrasound, x-rays of the digestive organs and endoscopy. By diagnosis, it is possible to determine the stage of development of the ulcer in the patient, the form of damage to the mucous membranes and the variety. The information obtained during the research allows us to determine the root cause of the development of pathology in the digestive tract.
The most common cause of peptic ulcer is Helicobacter pylori infection. For the treatment of gastritis and ulcers, provoked by this microorganism, it is indicated to take specific antibiotics.
Prescribing antibiotic drugs for pathology
An indication for the use of antibiotics for the stomach is the presence in the body of gastritis or peptic ulcer, infection with an infection confirmed by relevant studies.
If the pathology of the gastrointestinal tract has a non-bacterial origin, the use of antibiotic drugs is not required. As an independent indicated disease is quite rare. In most cases, the inflammatory process spreads throughout the body, affecting the nearest sections of the intestine.
The pharmaceutical market provides a wide selection of drugs, because of this it can be difficult to decide on a medicine. What antibiotic for pain in the stomach to choose? Let's figure it out.
Popular antibiotic drugs for the treatment of gastritis, peptic ulcer
The traditional therapy of ulcerative lesions in the duodenum and stomach involves the use of antibacterial drugs with a wide range of effects, used both in the treatment of gastrointestinal diseases and pathologies of the genitourinary system, respiratory system, brain, and skin integuments with bacterial etiology.
Of the large number of antibiotics for the stomach, experts recommend preparations of the following pharmacological groups:
- Macrolides (for example, Clarithromycin, Erythromycin).
- Semisynthetic penicillins ("Amoxicillin").
In clinical practice, there are also examples of the use in the treatment of gastric ulcer of the gastrointestinal tract not only of antibiotics, but also of antiprotozoal drugs, for example, Metronidazole. In rare cases, tetracycline is recommended for patients. It is prescribed in cases where alternative treatment did not allow to obtain the desired result or the patient has an individual intolerance to penicillin preparations.
When eradication therapy of diseases of the stomach, it is proposed to use a combination of agents that enhance the effect of each other.
Amoxicillin
"Amoxicillin" is a semi - synthetic antimicrobial drug that is part of the penicillin group. It has a wide range of effects, effective in combating Helicobacter pylori.
The manufacturer of this antibiotic for the stomach and intestines is available in several pharmacological forms - granules used for the manufacture of oral suspension, capsules, tablets. As a rule, in the treatment of gastrointestinal diseases, the use of tableted Amoxicillin is indicated. The drug does not affect the process of reproduction of microorganisms, however, it can destroy their cellular structures, thereby causing the death of bacteria.
With oral use, the drug is rapidly absorbed, as a result of which it is possible to achieve not only local, but also systemic effects on the infection.
Eating food does not affect the level of absorption of the drug, gastric juice is not capable of destroying the active component.
Combination with Metronidazole
In some cases, experts recommend combining the use of Amoxicillin with Metronidazole. Such a combination of drugs is contraindicated in patients suffering from diseases of the nervous system, impaired hematopoiesis, adverse reactions with nitroimidazole.
Against the background of the use of Amoxicillin, a number of undesirable reactions can develop, manifested in the form of pain in the joints, conjunctivitis, runny nose, rash, and allergic phenomena. With reduced immunity, the development of superinfection is not excluded. In the case of prolonged use of increased dosages of the drug, syncope, ataxia can occur.
With the parallel use of Amoxicillin with antimicrobial agents, their therapeutic effect is enhanced. It is forbidden to combine the indicated antibiotic with bacteriostatic drugs.
Clarithromycin
Clarithromycin is a semi-synthetic drug that has a wide range of effects. It is part of the group of macrolides, which are the safest antibiotic substances, since fewer negative manifestations develop against the background of their use.
The manufacturer comes in the form of tablets. The drug is effective in the fight against Helicobacter pylori, as it can disrupt the process of protein biosynthesis in the cellular structure of the microorganism.
Is it important to know how to drink an antibiotic - on an empty stomach or after eating?
You can take Clarithromycin, regardless of meals, as this affects the absorption of the active substance slightly.
The drug is partially destroyed under the influence of an acidic environment in the stomach, therefore, its optimal use will be with ulcerative lesions that develop under conditions of natural acidity.
A sufficient concentration of the active substance “Clarithromycin” on the gastric mucosa can be achieved by combining the drug with “Omeprazole”.
Adverse reactions
Negative manifestations during the use of this antibiotic develop quite rarely. In some cases, patients note sleep disturbances, taste changes, dyspepsia, nausea, and soreness in epigastrium.
The simultaneous use of "Clarithromycin" with "Simvastatin", "Lovastatin" is unacceptable. When combined with warfarin preparations, there is a risk of severe bleeding. Concurrent use with diabetes medications can provoke a toxic reaction, hypoglycemia.
"Metronidazole"
"Metronidazole" is an antibiotic with a wide spectrum of action, has antiprotozoal characteristics. The active substance in its composition is an imidazole derivative.
The manufacturer produces the drug in tablet form. Under the influence of the active component, DNA is destroyed in the molecules of the cells of the microorganism.
The drug is characterized by rapid absorption, when it enters the body, the necessary concentration occurs in a short time. The active substance is eliminated together with feces, urine.
When should you not use it?
The use of the drug with susceptibility to its components is unacceptable. Against the background of the use of Metronidazole, unpleasant symptoms may develop, for example, an allergic reaction, a skin rash, and digestive disorders. In some cases, visual disturbances, confusion, cramps, headache occur.
If the recommended dosages are exceeded, disorientation, vomiting reflex may develop.
It is forbidden to combine "Metronidazole" with busulfan, disulfaram, drugs containing ethanol.
With the simultaneous use of Metronidazole with lithium-based drugs, intoxication may occur.
Contraindications to the use of antibiotic agents
Antibiotics for gastric and duodenal ulcers are prohibited for patients in the following cases:
- renal failure, hepatic activity;
- in the lactation period;
- contraindication is pregnancy;
- allergic reactions to drug components;
- individual hypersensitivity to substances that are part of the drug.
In addition, each of these antibiotics has a number of specific contraindications peculiar only to him. For example:
- "Metronidazole" is contraindicated for use in sensitization of the body that provokes asthma.
- "Clarithromycin" is prohibited from porphyria.
- "Amoxicillin" is unacceptable to prescribe to patients suffering from lymphocytic leukemia pathological processes in the digestive system.
In the absence of the expected result from the use of antibiotics for gastric and duodenal ulcers, deterioration of the patient's condition, it is recommended to abandon therapy involving the use of these drugs. You also need to consult a specialist for advice and the appointment of another treatment regimen.
In the treatment of gastritis and ulcerative lesions using antibiotic drugs, it is important to exercise caution.
With exacerbations of the pathology in the gastrointestinal tract, the effectiveness of therapy can be achieved only by using antibiotics. For the speedy recovery of the body, you need to choose the most optimal drugs and treatment regimen. It is important to remember that only a timely appeal to a specialist and full compliance with his recommendations will achieve the best result.
What antibiotic for stomach ulcer to choose, the doctor will tell.