The medicine "Erythromycin" (tablets) is an antibiotic and belongs to the group of macrolides. The tablets are coated on top, which after use dissolves in the intestines. The drug has an antiseptic and antimicrobial effect.
After use, the drug "Erythromycin" (tablets) is distributed over most body fluids and tissues, and also binds to blood proteins. Metabolization of this drug occurs in the liver and its half-life with urine and bile is from one and a half to two hours.
The drug "Erythromycin" (tablets) - indications
The indicated remedy is prescribed in the presence of infectious and inflammatory diseases such as trachoma, diphtheria, brucellosis, whooping cough, tonsillitis, legionnaires disease, otitis media, scarlet fever, sinusitis, pneumonia, cholecystitis, syphilis and gonorrhea. Also, this tool is effective in the treatment of infectious and inflammatory diseases that are caused by pathogens resistant to penicillin, as well as chloramphenicol, tetracyclines and streptomycin.
In the form of ointment "Erythromycin" is used to treat juvenile acne.
The medicine "Erythromycin" (tablets) - instructions for use
First, the severity of the course of the infection and the tolerance of the drug are determined. The daily dose for an adult is at least 1 g, maximum 4 grams.
This tool can be used for children, but the recommended dose is much less:
- up to three months - 20-40 mg of the drug per kilogram of weight;
- 4 months - 18 years old - 30-50 milligrams of the drug per kilogram of the child’s weight.
The drug is taken up to 4 times a day, the duration of such treatment is from 5 to 14 days. If the symptoms of the disease have disappeared, do not abruptly stop treatment with the indicated medication, it must be used for another two days. It is possible to take the erythromycin antibiotic (tablets) both two to three hours after and one hour before a meal.
If a solution is used, then the affected skin is lubricated with it. The ointment is also applied to the lesion site or to the lower eyelid if eye diseases are being treated.
Possible side effects
After taking this medication, epigastric pain, nausea, cholestatic jaundice may occur. It is also possible the appearance of urticaria, anaphylactic shock and skin rash, candidiasis of the vagina or oral cavity.
Contraindications
Erythromycin tablets are not recommended for use in the presence of pronounced violations in the liver and hypersensitivity to macrolides.
Since erythromycin passes into breast milk, if necessary, it is necessary to stop breastfeeding the baby for a while.
While taking this drug, you should avoid the use of drugs that increase acidity, and also not to drink acidic drinks, as they significantly reduce the effect of erythromycin. All forms in which the erythromycin preparation is available are included in the List of Essential Drugs.
It is also worth noting that its use with chloramphenicol or lincomycin significantly weakens the effect of these agents.
If there is a need to take this antibiotic with drugs such as theophylline, aminophylline or caffeine, then you need to know that in this case the concentration of these substances in the blood plasma increases, and this in turn leads directly to the development of a toxic effect.
After taking erythromycin, the concentration of cyclosporine in the blood plasma increases, which can lead to the onset of nephrotoxicity.
If an intravenous administration of an erythromycin solution is carried out, then the action of ethanol is enhanced (gastric emptying is accelerated and the duration of the action of alcohol dehydrogenase in the stomach is reduced).