Ointment methyluracil with miramistin (according to the instructions) is a medicine that has a restoring, as well as anabolic and anti-inflammatory, antiseptic effect.
The drug is used to accelerate recovery processes during sluggish epithelization of wound surfaces and burns, bone fractures and other lesions of the skin and soft tissues.
Characteristic
Ointment "Methyluracil" with miramistin has a component of the same name that activates metabolic processes, and miramistin is a cationic antiseptic substance. The drug accelerates the regeneration processes, as well as the healing of wound surfaces.
Miramistin has an antimicrobial effect on many bacteria:
- Staphylococci.
- Streptococcus
- Aspergillus.
- Asporogenous yeast.
- Candida Glabrata.
- Candida Albicans.
- Trichophyton.
- Epidermophytosis.
- Microsporia.
- Fungus Malassesia.
The drug reduces the resistance of bacteria and fungi to antibacterial agents. With the help of a wide range of antimicrobial effects, miramistin effectively prevents infection of wounds and burns, stimulating recovery processes.
The drug is characterized by a soft osmotic effect, which helps to clean and dry the wound surface.
The active components of the ointment "Methyluracil" with miramistin are not absorbed into the general bloodstream and, as a rule, do not provoke a systemic effect. The medication is a pyrimidine derivative. According to therapeutic activity, "Methyluracil" refers to activators of tissue regeneration. It consists of components that can renew dead tissue and organ sites.
The medication has pronounced anabolic and anti-catabolic effects. Under its influence, biological protein synthesis occurs and the excretion of potassium, sulfur and phosphorus is reduced.
"Methyluracil" activates cell repair, accelerates wound healing and improves immunity. A medicine in the form of an ointment belongs to an over-the-counter group of medicines and is dispensed without a doctor’s prescription.
Structure
The country of manufacture of the ointment "Methyluracil" with miramistin - Ukraine, company: "FF Darnitsa". The tool contains:
- methyluracil;
- miramistin;
- propylene glycol;
- macrogol 400;
- poloxamer;
- cetyl alcohol;
- stearyl alcohol;
- water.
Indications for the use of ointment "Methyluracil" with miramistin
The drug is recommended for use with the following problems:
- Deep wound surfaces.
- Pressure ulcers (death of soft tissues that arise as a result of a violation of their nutrition and prolonged pressure on a specific area of the body).
- Fractures of bones. Intertrigo (inflammatory lesion by bacteria, as well as fungi or viruses of folds of the skin, which subsequently appears irritating and prolonged moisturizing effects of skin secretion products).
- Cracks.
- Burn lesions of the skin.
- Dermatitis (an inflammatory lesion of the skin that appears as a result of the influence of factors of a chemical, physical or biological nature).
- Photodermatosis (an inflammatory process on the skin as a result of hypersensitivity to both direct and reflected sunlight).
- Radioepithelitis (a disease that develops after exposure to ionizing radiation).
- Vaginal disease.
Limitations and unwanted reactions
The composition of the ointment "Methyluracil" with miramistin contains substances that cause allergic manifestations. Therefore, in order to avoid other side effects, it is necessary to know the restrictions on the use:
- Hypergranulation of the wound (an edema replacing the edema melts dead tissue and cleanses the wound, and as it is completed, granulations begin to develop, gradually filling the defect that has arisen).
- Acute leukemia (an oncological disease that occurs as a result of pathological reproduction of immature blood cells).
- Chronic forms of leukemia.
- Lymphogranulomatosis (malignant hyperplasia of lymphoid tissue, a characteristic feature of which is the formation of granulomas with Berezovsky-Sternberg cells).
- Malignant bone marrow diseases.
From the instructions for the ointment "Methyluracil" with miramistin, it is known that with special care it is recommended to use the medication for patients with tumors that undergo radiation and chemotherapy.
The effectiveness of the drug is enhanced if it is applied directly to the wound, previously washed with a solution. The presence of purulent and necrotic masses requires an additional consumption of liniment.
According to the instructions, the ointment "Methyluracil" with miramistin should be applied with extreme caution in case of skin diseases that are accompanied by the formation of strong growths of the epidermis:
- Verrucous form of lichen planus (chronic inflammatory, common skin disease).
- Vegetative pemphigus (a chronic dermatological disease from the group of bladder injuries, in which, after elimination of the bladder, small growths form at the bottom of the erosive lesion).
- Verrucous epidermodysplasia (a hereditary disease that manifests as a warty rash prone to malignant transformation).
The drug must be used with extreme caution in acute inflammatory lesions of the skin and during exacerbation of chronic diseases.
According to the instructions, the ointment "Methyluracil" with miramistin side effects causes the following:
- irritation;
- hyperemia (overflow of blood vessels of the circulatory system of any organ or body area);
- burning.
Mode of application
Ointment is used externally twice a day. A single concentration of the drug should not exceed 20 grams. The drug is applied in a thin layer on the wound surface.
According to the instructions for the drug, it is known that the duration of therapy depends on the degree and area of the lesion, and can reach up to 30 days. For radioepithelitis and uterine diseases, Methyluracil is applied with loose swabs.
In the presence of trophic ulcers on the legs, their treatment is as follows: before applying the ointment, you need to rinse the affected surface with antiseptic agents and eliminate purulent and necrotic masses with a bandage.
Features
Like any other medicine, "Methyluracil" has its own nuances in use:
- The medication should be applied only according to strict indications.
- The medicine enhances the anti-radiation effect of "Cystamine".
- The active component is combined with antibacterial, antiseptic agents, as well as with "sulfonamides."
Substitutes
"Methyluracil" in the form of an ointment is produced by many Russian companies. The trade name of the drug corresponds to the chemical name of the active ingredient. The concentration of the active substance as a standard is 10%, the volume of the tube is 15 and 25 grams. Similar generics are:
- "Stizamet" is used in the chronic form of diseases, the duration of therapy can reach 2 months. Manufacturing company: "Retinoids" (Russia).
- "Meturakol" contains 50 milligrams of methyluracil and up to 1 gram of fibrillar protein. The ointment is applied to the wound surface and fixed with a bandage. It is made by Belkozin firm (Russia).
Combined views:
- "Levomekol" is a combination of methyluracil and chloramphenicol. The latter is an antibacterial component that has a wide range of effects. With its use, both bacteriostatic and antibacterial actions occur. The ointment is produced by the company NIZHFARM (Russia).
- Hyposol. The structure of the medication includes methyluracil, as well as sea buckthorn oil and sulfaethidol. It is produced in the form of a spray, which has found extensive use in the fields of gynecology, surgery, dentistry, proctology. Manufacturer: "Altivitamins" (Russia).
- "Fusimet" is a complex medicine based on methyluracil and sodium fusidate. The drug has increased effectiveness against staphylococci, gonococci, hemophilic bacillus and corynebacteria, less effective in case of streptococcal lesions. It is used to eliminate folliculitis, burns and other infected lesions of the skin. Manufacturer: OAO Biosynthesis.
How to store medicine
According to the instructions, the ointment "Methyluracil" with miramistin should be kept at a temperature of up to 25 degrees in a dry place, away from children. Shelf life is 2 years. The cost of the drug varies from 40 to 200 rubles.
Conclusion
Ointment "Methyluracil" with miramistin provides the formation of a dry scab, with no visible signs of a wetting wound. In this case, the drug preserves the granulation of healthy cells and improves tissue epithelization.
In addition, the composition does not provoke irritation and allergies. With trophic ulcers on the legs, their treatment and regimen is prescribed by a medical specialist.
With external use, miramistin is not absorbed into the mucous membranes and skin. When combined with methyluracil, it can be partially absorbed into the bloodstream, which activates its resorption abilities. When using the drug "Methyluracil" you can achieve the following result:
- Small wounds grow faster.
- The recovery process of deep damage is accelerated.
- The formation of purulent exudate is prevented.
- Postoperative sutures are quicker to tighten.
- Pressure sores are prevented.
- Bacteria and fungi are eliminated.
Opinions
According to reviews, the ointment "Methyluracil" with miramistin for burns effectively eliminates the problem. In addition, the medication also effectively helps to eliminate new stretch marks and makes old ones less noticeable. Therefore, the majority of the fair half after the birth of a child use it not only as a drug, but also as a cosmetic mixture to improve the condition of the skin on the abdomen, as well as hips and buttocks.
In addition, this drug is popular with people suffering from acne and comedones, as it dries acne, and there are no scars from wounds.
The drug "Methyluracil" with miramistin can also be used in the treatment of hemorrhoids. It not only quickly tightens bleeding cracks, but also relieves pain, prevents suppuration, helps to heal the skin without scars and scars.