What is the ubistezin forte drug for? Instructions, as well as indications for the use of this medication will be presented later.
From the materials in this article you will learn about the form in which the said product is produced, how much it costs, whether it can be prescribed to pregnant women, and what properties it has.
Composition, packaging and form
The drug "Ubistesin forte", the price of which is indicated below, is available in the form of a solution for injection. Its active ingredients are articaine hydrochloride and epinephrine hydrochloride. Also, the composition of the medication includes auxiliary components in the form of water for injection, sodium chloride and sodium sulfite.
Injection solution is marketed in carpules that are placed in a metal container.
Pharmacodynamics of the drug
What is a drug like Ubistesin Forte? According to the instructions, this is a combination product intended for local anesthesia. It is used for minor surgical interventions, in particular in dental practice.
The effect of this medication is determined by the substances that make up its composition.
Local anesthetics containing articaine belong to the anesthetics of the thiaphene group.
Compared with lidocaine or novocaine, such a drug is characterized by instant action. Anesthetic effect is observed after 0.5-3 minutes. As for the above funds, they begin to work only after 4-5 and 5-10 minutes, respectively.
The duration of the anesthetic effect after administration of the ubistezin forte drug is 45 minutes.
It should be especially noted that this medication is two times stronger than lidocaine. Moreover, it is very quickly excreted from the body, does not inhibit wound healing and is less toxic. Such an injection is indicated for the elderly, as well as children from 5 years.
As for epinephrine, it is a vasoconstrictor. It contributes to the narrowing of blood vessels, thereby enhancing and prolonging the action of the anesthetic. Such an effect of a drug substance entails tissue hypoxia, as a result of which the excitability of nerve endings is suppressed, which significantly reduces pain.
The drug "Ubistezin Forte" is an anesthetic with a low content of vasoconstrictor. A small amount of epinephrine does not increase blood pressure, does not cause tachycardia and does not have a pronounced effect on the cardiovascular system.
Pharmacokinetics of Injection
Local anesthetics have high penetration. And the drug we are considering is no exception. It binds to plasma proteins by 95% and practically does not stand out with a woman’s milk and does not penetrate the placental barrier.
The half-life of such a drug is 22-26 minutes.
Indications for use
The drug "Ubistezin Forte" is actively used for minor dental operations:
- with uncomplicated tooth extraction;
- when filling carious teeth;
- in preparation for prosthetics or the so-called grinding of teeth.
It should also be noted that the medication in question is used during intercostal, retrobulbar and paravertebral anesthesia, blockade of the stellate node, trigeminal nerve, external genitalia and brachial plexus.
Contraindications
Injection solution "Ubistesin forte" is not recommended for use with:
- bronchial asthma and hypersensitivity to sulfites;
- angle-closure glaucoma;
- hypersensitivity to drug substances;
- paroxysmal tachycardia;
- severe liver failure;
- cardiogenic shock;
- concomitant therapy with tricyclic antidepressants and non-selective beta-blockers;
- hyperthyroidism.
Cautious use of solution
With extreme caution, this medication is prescribed for:
- diabetes mellitus;
- chronic heart failure;
- arterial hypertension;
- atrioventricular block;
- renal failure;
- inflammation in the field of anesthesia;
- in old age;
- weakened condition of the patient.
How to apply the solution "Ubistesin forte"?
The medication in question can be used in relation to healthy people with minor dental interventions. About 1-2 carpules are used at a time, which corresponds to 2-4 ml. The maximum allowable dose of this solution for 2 hours is 2.5-3 carpules.
With uncomplicated tooth extraction, the drug is administered under the mucosa in an amount of 1.7 ml (per tooth).
When cutting the palate, 0.1 ml of the solution is used, when suturing the perineum - about 5-15 ml, and with tonsillectomy - 5-10 ml (per tonsil).
If the medication is used for conduction anesthesia (for example, intercostal, retrobulbar, epidural, paravertebral or sacral), as well as for blockages (trigeminal nerve, paracervical, brachial plexus or stellate node), then doctors use from 1 to 30 ml of solution (depending on the volume anesthesia and injection site).
Side effects
According to the instructions, the drug in question can cause the following adverse reactions:
- nausea, “clouding” in the eyes, vomiting, nerve damage;
- headache, redness of the skin, muscle tremor, tachycardia;
- impaired consciousness (possible loss of consciousness) and breathing, a drop in blood pressure, muscle twitching;
- generalized convulsions, itching, conjunctivitis, inhibition of cardiovascular activity;
- swelling at the injection site, swelling of the lips, rhinitis.
Overdose symptoms
An overdose of this drug causes the following undesirable symptoms: tachycardia, dizziness, impaired consciousness, bradycardia, anxiety, decreased blood pressure.
When observing such deviations, it is required to stop all manipulations, lay the patient and restore airway patency. You should also regularly monitor the heart rate and blood pressure of the patient.
The victim is shown mechanical ventilation. In case of seizures, the patient is injected intravenously with barbiturates, with vascular collapse - “Adrenaline”, with shock - electrolytes and glucocorticosteroids, with tachycardia - selective beta-blockers, and with an increase in blood pressure - peripheral vasodilators.
The period of gestation, feeding
Can “Ubistezin Forte” be used during pregnancy? Experts report that this drug does not pass through the placental barrier. In this regard, it is an absolutely safe anesthetic that has no effect on the fetus.
As for nursing mothers, they should not interrupt breastfeeding, since the active substances of the drug are not excreted along with milk.
Reviews and price
The cost of this tool varies between 2000-2100 rubles (for 50 karpul).
Dentists speak about the drug in question exclusively on the positive side. The effectiveness of this medication is due to many factors.
A high percentage of binding of the active substance to proteins indicates that about 95% of the drug enters the bloodstream as an inactive substance. In this regard, we can safely conclude that the systemic toxicity of this drug is very low. Moreover, the effectiveness of anesthesia is quite high.
It should be noted that the "Ubistezin Forte" is very rapidly excreted from the body. If a second injection is required, then the toxic effect of this medication will be noticeably lower than that of other anesthetics.