Vestibo tablets contain betahistine dihydrochloride. The medicine has a histamine-like, vasodolating effect. Due to the direct agonistic effect on H1 receptors in the vessels of the inner ear and in the sphincters of the (precapillary) microvasculature and the indirect effect on H3 receptors, it improves permeability and microcirculation in the capillary system, stabilizes the pressure of the endolymph in the cochlea and the labyrinth, and increases blood flow to the basilar artery. The medicine eliminates disorders of both the cochlear and vestibular apparatus. In particular, the medication helps to reduce the intensity and frequency of dizziness, tinnitus, and improve auditory function in case of its disorders. The tool does not have sedative activity, does not provoke drowsiness. The medication undergoes rapid absorption. The drug practically does not bind to plasma proteins.
The maximum concentration is noted three hours after administration. Excretion is carried out in the form of a metabolite in the urine.
Means "Vestibo". Indications for use. Price
The medicine is prescribed for labyrinth and vestibular disorders. In particular, the medication is effective for noise or earaches, dizziness, vomiting, nausea, headache, hearing loss. The drug “Vestibo” recommends the use instructions for labyrinthitis, vestibular neuritis, benign positional vertigo (after neurosurgical interventions, including), with Meniere's syndrome, dropsy of the labyrinth in the inner ear. As part of the combined effect, the drug is prescribed for encephalopathy (post-traumatic), vertebrobasilar insufficiency, atherosclerotic lesions in the vessels of the brain. The cost of the medicine is from 120 r.
Contraindications
The medicine “Vestibo” is not prescribed (instructions for use warns about this) with pheochromocytoma, hypersensitivity, bronchial asthma. Contraindications include pregnancy, peptic ulcer in the duodenum and stomach (exacerbation). Caution is exercised in the treatment of patients in childhood. Dose adjustment is necessary in the presence of anamnestic data on peptic ulcer in the digestive tract. The advisability of prescribing in the 2nd and 3rd trimesters of the antenatal period is determined by the doctor.
Side effects
The negative effects of therapy with Vestibo medication include Quincke's edema, dyspeptic symptoms, and skin rash.
Dosage regimen
The medicine is drunk with food. Drink recommended liquid in a small volume. The drug "Vestibo" instructions for use recommends taking a long period. Means with a dosage of 8 and 16 mg are prescribed for 1-2 tablets. The frequency of administration is 2-4 p / d. A drug with a dosage of 24 mg is taken at 0.5-1 tab twice a day. The maximum allowable amount of medication per day is 48 mg.
additional information
In some cases, the therapeutic result is observed only after a few months of administration. In case of an overdose, adverse reactions intensify, tachycardia occurs, pressure decreases, bronchospasm is likely. Recommended treatment according to symptoms.